Publicação
Chemical characterization and bioactivity evaluation of black mulberry and grape seeds
| Resumo: | Circular economy is increasingly seen as a crucial way to reduce food by- products and residues and obtain valuable raw materials. There is a growing demand for industrial products with clean labels and bio benefits, where natural bioactive compounds play an important role. Among these natural biomolecules, polyphenols stand out for their health benefits against diseases such as cancer or diabetes. Thus, the use of agro-industrial bioresidues as a rich source of polyphenols for the development of new natural preservatives, colorants and nutraceuticals is in the spotlight [1,2]. The aim of this work was the recovery of polyphenols from grape and mulberry seeds, usually considered as biowaste. Polyphenols were characterized by HPLC-DAD- ESI/MSn, and the obtained polyphenol-rich extracts were analysed for their bioactive properties, namely antimicrobial and antioxidant capacities. Grape seeds were richer in catechin oligomers (36.0 ± 0.3 mg/g), and mulberry seeds in ellagic acid derivatives (3.14 ± 0.02 mg/g). In addition, both extracts exhibited high antimicrobial activity against multi-resistant Staphylococcus aureus. On the other hand, mulberry seeds showed the strongest antioxidant activity by the lipid peroxidation inhibition (IC50 = 23 ± 2 μg/mL) and oxidative haemolysis inhibition (IC50 at a 60 min Δt = 46.0 ± 0.8 μg/mL) methods [2]. Both by-products could be exploited for the recovery of added-value bioactive polyphenols and further application in the industry [2]. |
|---|---|
| Autores principais: | Gómez-Mejía, Esther |
| Outros Autores: | Roriz, Custódio Lobo; Heleno, Sandrina A.; Calhelha, Ricardo C.; Dias, Maria Inês; Pinela, José; Rosales-Conrado, Noelia; León-González, María Eugenia; Ferreira, Isabel C.F.R.; Barros, Lillian |
| Assunto: | Bioactivity Polyphenols By-products Grape/mulberry seeds |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | documento de conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1863850773030371328 |
|---|---|
| author | Gómez-Mejía, Esther |
| author2 | Roriz, Custódio Lobo Heleno, Sandrina A. Calhelha, Ricardo C. Dias, Maria Inês Pinela, José Rosales-Conrado, Noelia León-González, María Eugenia Ferreira, Isabel C.F.R. Barros, Lillian |
| author2_role | author author author author author author author author author |
| author_facet | Gómez-Mejía, Esther Roriz, Custódio Lobo Heleno, Sandrina A. Calhelha, Ricardo C. Dias, Maria Inês Pinela, José Rosales-Conrado, Noelia León-González, María Eugenia Ferreira, Isabel C.F.R. Barros, Lillian |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Gómez-Mejía, Esther\"},{\"Person.name\":\"Roriz, Custódio Lobo\",\"Person.identifier.orcid\":\"0000-0002-4021-1078\"},{\"Person.name\":\"Heleno, Sandrina A.\",\"Person.identifier.orcid\":\"0000-0001-7224-1098\"},{\"Person.name\":\"Calhelha, Ricardo C.\",\"Person.identifier.orcid\":\"0000-0002-6801-4578\"},{\"Person.name\":\"Dias, Maria Inês\",\"Person.identifier.orcid\":\"0000-0001-8744-7814\"},{\"Person.name\":\"Pinela, José\",\"Person.identifier.orcid\":\"0000-0001-7523-1637\"},{\"Person.name\":\"Rosales-Conrado, Noelia\"},{\"Person.name\":\"León-González, María Eugenia\"},{\"Person.name\":\"Ferreira, Isabel C.F.R.\",\"Person.identifier.orcid\":\"0000-0003-4910-4882\"},{\"Person.name\":\"Barros, Lillian\",\"Person.identifier.orcid\":\"0000-0002-9050-5189\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Gómez-Mejía, Esther Roriz, Custódio Lobo Heleno, Sandrina A. Calhelha, Ricardo C. Dias, Maria Inês Pinela, José Rosales-Conrado, Noelia León-González, María Eugenia Ferreira, Isabel C.F.R. Barros, Lillian |
| datacite.date.Accepted.fl_str_mv | 2021-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2022-01-25T11:57:04Z |
| datacite.date.embargoed.fl_str_mv | 2022-01-25T11:57:04Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Bioactivity Polyphenols By-products Grape/mulberry seeds |
| datacite.titles.title.fl_str_mv | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Gómez-Mejía, Esther Roriz, Custódio Lobo Heleno, Sandrina A. Calhelha, Ricardo C. Dias, Maria Inês Pinela, José Rosales-Conrado, Noelia León-González, María Eugenia Ferreira, Isabel C.F.R. Barros, Lillian |
| dc.date.Accepted.fl_str_mv | 2021-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2022-01-25T11:57:04Z |
| dc.date.embargoed.fl_str_mv | 2022-01-25T11:57:04Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/24898 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Bioactivity Polyphenols By-products Grape/mulberry seeds |
| dc.title.fl_str_mv | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_c94f |
| description | Circular economy is increasingly seen as a crucial way to reduce food by- products and residues and obtain valuable raw materials. There is a growing demand for industrial products with clean labels and bio benefits, where natural bioactive compounds play an important role. Among these natural biomolecules, polyphenols stand out for their health benefits against diseases such as cancer or diabetes. Thus, the use of agro-industrial bioresidues as a rich source of polyphenols for the development of new natural preservatives, colorants and nutraceuticals is in the spotlight [1,2]. The aim of this work was the recovery of polyphenols from grape and mulberry seeds, usually considered as biowaste. Polyphenols were characterized by HPLC-DAD- ESI/MSn, and the obtained polyphenol-rich extracts were analysed for their bioactive properties, namely antimicrobial and antioxidant capacities. Grape seeds were richer in catechin oligomers (36.0 ± 0.3 mg/g), and mulberry seeds in ellagic acid derivatives (3.14 ± 0.02 mg/g). In addition, both extracts exhibited high antimicrobial activity against multi-resistant Staphylococcus aureus. On the other hand, mulberry seeds showed the strongest antioxidant activity by the lipid peroxidation inhibition (IC50 = 23 ± 2 μg/mL) and oxidative haemolysis inhibition (IC50 at a 60 min Δt = 46.0 ± 0.8 μg/mL) methods [2]. Both by-products could be exploited for the recovery of added-value bioactive polyphenols and further application in the industry [2]. |
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| funding.funder.alternateName_str_mv | FCT FCT |
| funding.funder.identifier_str_mv | http://doi.org/10.13039/501100001871 http://doi.org/10.13039/501100001871 |
| funding.funder.name_str_mv | Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia |
| funding.name_str_mv | 6817 - DCRRNI ID POR_NORTE |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10198/24898 |
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| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
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| person_str_mv | Gómez-Mejía, Esther Roriz, Custódio Lobo Roriz, Custódio Lobo https://www.ciencia-id.pt/9519-D97C-6B17 9519-D97C-6B17 http://orcid.org/0000-0002-4021-1078 0000-0002-4021-1078 Heleno, Sandrina A. Heleno, Sandrina A. https://www.ciencia-id.pt/8B18-3095-6FC9 8B18-3095-6FC9 http://orcid.org/0000-0001-7224-1098 0000-0001-7224-1098 Calhelha, Ricardo C. Calhelha, Ricardo C. https://www.ciencia-id.pt/F313-E3CE-554E F313-E3CE-554E http://orcid.org/0000-0002-6801-4578 0000-0002-6801-4578 Dias, Maria Inês Dias, Maria Inês https://www.ciencia-id.pt/2A13-4BE6-C7CF 2A13-4BE6-C7CF http://orcid.org/0000-0001-8744-7814 0000-0001-8744-7814 Pinela, José Pinela, José https://www.ciencia-id.pt/771C-2B43-B108 771C-2B43-B108 http://orcid.org/0000-0001-7523-1637 0000-0001-7523-1637 Rosales-Conrado, Noelia León-González, María Eugenia Ferreira, Isabel C.F.R. Ferreira, Isabel C.F.R. https://www.ciencia-id.pt/9418-CF95-9919 9418-CF95-9919 http://orcid.org/0000-0003-4910-4882 0000-0003-4910-4882 Barros, Lillian Barros, Lillian https://www.ciencia-id.pt/9616-35CB-D001 9616-35CB-D001 http://orcid.org/0000-0002-9050-5189 0000-0002-9050-5189 |
| publishDate | 2021 |
| reponame_str | Biblioteca Digital do IPB |
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| spelling | engpt_PTCircular economy is increasingly seen as a crucial way to reduce food by- products and residues and obtain valuable raw materials. There is a growing demand for industrial products with clean labels and bio benefits, where natural bioactive compounds play an important role. Among these natural biomolecules, polyphenols stand out for their health benefits against diseases such as cancer or diabetes. Thus, the use of agro-industrial bioresidues as a rich source of polyphenols for the development of new natural preservatives, colorants and nutraceuticals is in the spotlight [1,2]. The aim of this work was the recovery of polyphenols from grape and mulberry seeds, usually considered as biowaste. Polyphenols were characterized by HPLC-DAD- ESI/MSn, and the obtained polyphenol-rich extracts were analysed for their bioactive properties, namely antimicrobial and antioxidant capacities. Grape seeds were richer in catechin oligomers (36.0 ± 0.3 mg/g), and mulberry seeds in ellagic acid derivatives (3.14 ± 0.02 mg/g). In addition, both extracts exhibited high antimicrobial activity against multi-resistant Staphylococcus aureus. On the other hand, mulberry seeds showed the strongest antioxidant activity by the lipid peroxidation inhibition (IC50 = 23 ± 2 μg/mL) and oxidative haemolysis inhibition (IC50 at a 60 min Δt = 46.0 ± 0.8 μg/mL) methods [2]. Both by-products could be exploited for the recovery of added-value bioactive polyphenols and further application in the industry [2].application/pdfpt_PTChemical characterization and bioactivity evaluation of black mulberry and grape seedsGómez-Mejía, EstherPersonalRoriz, Custódio LoboDSpacehttp://dspace.org/items/d13ab9dd-af85-4652-bae4-88b2a9034d79DSpacehttp://dspace.org/items/d13ab9dd-af85-4652-bae4-88b2a9034d79RorizCustódio LoboCiência IDhttps://www.ciencia-id.pt9519-D97C-6B17ORCIDhttp://orcid.org0000-0002-4021-1078Scopus Author IDhttps://www.scopus.com56151637600PersonalHeleno, Sandrina A.DSpacehttp://dspace.org/items/e89b5bf5-d315-49b6-871e-fa8eb6030676DSpacehttp://dspace.org/items/e89b5bf5-d315-49b6-871e-fa8eb6030676HelenoSandrina A.Ciência IDhttps://www.ciencia-id.pt8B18-3095-6FC9ORCIDhttp://orcid.org0000-0001-7224-1098Researcher IDhttps://www.researcherid.comL-5951-2014Scopus Author IDhttps://www.scopus.com30067731800PersonalCalhelha, Ricardo C.DSpacehttp://dspace.org/items/2d5d1a41-7561-4a01-871c-b4c97da35053DSpacehttp://dspace.org/items/2d5d1a41-7561-4a01-871c-b4c97da35053CalhelhaRicardo C.Ciência IDhttps://www.ciencia-id.ptF313-E3CE-554EORCIDhttp://orcid.org0000-0002-6801-4578Researcher IDhttps://www.researcherid.comJ-2172-2014Scopus Author IDhttps://www.scopus.com6507978333PersonalDias, Maria InêsDSpacehttp://dspace.org/items/7ca8432b-e7f4-4116-a56e-9eba0d4403bdDSpacehttp://dspace.org/items/7ca8432b-e7f4-4116-a56e-9eba0d4403bdDiasMaria InêsCiência IDhttps://www.ciencia-id.pt2A13-4BE6-C7CFORCIDhttp://orcid.org0000-0001-8744-7814Researcher IDhttps://www.researcherid.comM-8242-2013Scopus Author IDhttps://www.scopus.com54388787000PersonalPinela, JoséDSpacehttp://dspace.org/items/706cd9ff-065b-4c98-98a7-5c0a9e45adc4DSpacehttp://dspace.org/items/706cd9ff-065b-4c98-98a7-5c0a9e45adc4PinelaJoséCiência IDhttps://www.ciencia-id.pt771C-2B43-B108ORCIDhttp://orcid.org0000-0001-7523-1637Researcher IDhttps://www.researcherid.comB-4466-2014Scopus Author IDhttps://www.scopus.com54392272800Rosales-Conrado, NoeliaLeón-González, María EugeniaPersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600PersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf978-83-65955-53-12022-01-25T11:57:04Z20212021-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/24898http://purl.org/coar/access_right/c_abf2open accessBioactivityPolyphenolsBy-productsGrape/mulberry seeds748796 bytesFundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaDevelopment of a new colouring agent from Gomphrena globosa L.: optimization of the extraction process, stability studies and proof-of-concept in a food matrixPOR_NORTECrossref Funder IDhttp://doi.org/10.13039/501100001871other research producthttp://purl.org/coar/resource_type/c_c94fconference object2021http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/65d86501-e078-4b7a-b2a7-55ed3eb4e553/download1st International Meeting for Young Analytical Chemists |
| spellingShingle | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds Gómez-Mejía, Esther Bioactivity Polyphenols By-products Grape/mulberry seeds |
| subject.fl_str_mv | Bioactivity Polyphenols By-products Grape/mulberry seeds |
| title | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| title_full | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| title_fullStr | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| title_full_unstemmed | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| title_short | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| title_sort | Chemical characterization and bioactivity evaluation of black mulberry and grape seeds |
| topic | Bioactivity Polyphenols By-products Grape/mulberry seeds |
| topic_facet | Bioactivity Polyphenols By-products Grape/mulberry seeds |
| url | http://hdl.handle.net/10198/24898 |
| visible | 1 |