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Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes

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Resumo:Grape agri-food wastes, such as skin, seeds, and other discarded by-products, contain phytochemical compounds that offer potential health benefits. Methods: This study aimed to investigate the polyphenol composition and bioactivities of different extracts obtained from grape marc and seeds, with the goal of exploring their potential for application as natural food additives. Results: Regardless of the extraction method used (dynamic maceration, ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE)), all extracts exhibited relatively high concentrations of phenolic compounds. The chemical characterization of the extracts revealed the presence of specific compounds and chemical groups associated with each extraction methodology. Moreover, the extracts displayed satisfactory antioxidant activities, especially in inhibiting lipoperoxidation as assessed by the TBARS assay. Additionally, the extracts demonstrated effective inhibition against different strains of bacteria and fungi known as food contaminants. Taken together, these findings indicate that those extracts have the potential to be tested as natural antioxidants and preservatives with sustainable origins in food and beverage systems. Among the extraction methods evaluated, traditional maceration and UAE provided extracts with the highest antioxidant and antimicrobial activities. Conclusions: Our results suggest the opportunity to explore grape marc and seeds discarded by the winery industry in Portugal as natural sources of bioactive compounds, which could be employed as functional food ingredients or technological additives. The valorization of grape biowastes offers a promising strategy to reduce waste and harness their potential health benefits.
Autores principais:Ueda, Jonata Massao
Outros Autores:Griebler, Karoline Ribeiro; Finimundy, Tiane C.; Rodrigues, Daniele Bobrowski; Verissimo, Lavinia; Pires, Tânia C.S.P.; Gonçalves, João Carlos B.; Fernandes, Isabel P.; Pereira, Eliana; Barros, Lillian; Heleno, Sandrina A.; Calhelha, Ricardo C.
Assunto:Grape marc By-products Phenolic compounds Antioxidant Antimicrobial
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Ueda, Jonata Massao
author2 Griebler, Karoline Ribeiro
Finimundy, Tiane C.
Rodrigues, Daniele Bobrowski
Verissimo, Lavinia
Pires, Tânia C.S.P.
Gonçalves, João Carlos B.
Fernandes, Isabel P.
Pereira, Eliana
Barros, Lillian
Heleno, Sandrina A.
Calhelha, Ricardo C.
author2_role author
author
author
author
author
author
author
author
author
author
author
author_facet Ueda, Jonata Massao
Griebler, Karoline Ribeiro
Finimundy, Tiane C.
Rodrigues, Daniele Bobrowski
Verissimo, Lavinia
Pires, Tânia C.S.P.
Gonçalves, João Carlos B.
Fernandes, Isabel P.
Pereira, Eliana
Barros, Lillian
Heleno, Sandrina A.
Calhelha, Ricardo C.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
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datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Ueda, Jonata Massao
Griebler, Karoline Ribeiro
Finimundy, Tiane C.
Rodrigues, Daniele Bobrowski
Verissimo, Lavinia
Pires, Tânia C.S.P.
Gonçalves, João Carlos B.
Fernandes, Isabel P.
Pereira, Eliana
Barros, Lillian
Heleno, Sandrina A.
Calhelha, Ricardo C.
datacite.date.Accepted.fl_str_mv 2023-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2023-12-18T09:52:46Z
datacite.date.embargoed.fl_str_mv 2023-12-18T09:52:46Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Grape marc
By-products
Phenolic compounds
Antioxidant
Antimicrobial
datacite.titles.title.fl_str_mv Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Ueda, Jonata Massao
Griebler, Karoline Ribeiro
Finimundy, Tiane C.
Rodrigues, Daniele Bobrowski
Verissimo, Lavinia
Pires, Tânia C.S.P.
Gonçalves, João Carlos B.
Fernandes, Isabel P.
Pereira, Eliana
Barros, Lillian
Heleno, Sandrina A.
Calhelha, Ricardo C.
dc.date.Accepted.fl_str_mv 2023-01-01T00:00:00Z
dc.date.available.fl_str_mv 2023-12-18T09:52:46Z
dc.date.embargoed.fl_str_mv 2023-12-18T09:52:46Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/28957
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv MDPI
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Grape marc
By-products
Phenolic compounds
Antioxidant
Antimicrobial
dc.title.fl_str_mv Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Grape agri-food wastes, such as skin, seeds, and other discarded by-products, contain phytochemical compounds that offer potential health benefits. Methods: This study aimed to investigate the polyphenol composition and bioactivities of different extracts obtained from grape marc and seeds, with the goal of exploring their potential for application as natural food additives. Results: Regardless of the extraction method used (dynamic maceration, ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE)), all extracts exhibited relatively high concentrations of phenolic compounds. The chemical characterization of the extracts revealed the presence of specific compounds and chemical groups associated with each extraction methodology. Moreover, the extracts displayed satisfactory antioxidant activities, especially in inhibiting lipoperoxidation as assessed by the TBARS assay. Additionally, the extracts demonstrated effective inhibition against different strains of bacteria and fungi known as food contaminants. Taken together, these findings indicate that those extracts have the potential to be tested as natural antioxidants and preservatives with sustainable origins in food and beverage systems. Among the extraction methods evaluated, traditional maceration and UAE provided extracts with the highest antioxidant and antimicrobial activities. Conclusions: Our results suggest the opportunity to explore grape marc and seeds discarded by the winery industry in Portugal as natural sources of bioactive compounds, which could be employed as functional food ingredients or technological additives. The valorization of grape biowastes offers a promising strategy to reduce waste and harness their potential health benefits.
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Fundação para a Ciência e a Tecnologia
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person_str_mv Ueda, Jonata Massao
Ueda, Jonata Massao
https://www.ciencia-id.pt/4417-F90B-68A3
4417-F90B-68A3
http://orcid.org/0000-0002-1452-3764
0000-0002-1452-3764
Griebler, Karoline Ribeiro
Finimundy, Tiane C.
Finimundy, Tiane C.
https://www.ciencia-id.pt/2F18-67B1-776A
2F18-67B1-776A
http://orcid.org/0000-0003-3516-0795
0000-0003-3516-0795
Rodrigues, Daniele Bobrowski
Rodrigues, Daniele Bobrowski
https://www.ciencia-id.pt/A91B-FE1D-B275
A91B-FE1D-B275
http://orcid.org/0000-0003-0260-5751
0000-0003-0260-5751
Verissimo, Lavinia
Pires, Tânia C.S.P.
Pires, Tânia C.S.P.
https://www.ciencia-id.pt/321E-2D96-00CA
321E-2D96-00CA
http://orcid.org/0000-0002-3954-3833
0000-0002-3954-3833
Gonçalves, João Carlos B.
Fernandes, Isabel P.
Fernandes, Isabel P.
https://www.ciencia-id.pt/4D1C-441F-C7F0
4D1C-441F-C7F0
http://orcid.org/0000-0002-0069-4503
0000-0002-0069-4503
Pereira, Eliana
Pereira, Eliana
https://www.ciencia-id.pt/BE17-462D-9A75
BE17-462D-9A75
http://orcid.org/0000-0003-2854-6745
0000-0003-2854-6745
Barros, Lillian
Barros, Lillian
https://www.ciencia-id.pt/9616-35CB-D001
9616-35CB-D001
http://orcid.org/0000-0002-9050-5189
0000-0002-9050-5189
Heleno, Sandrina A.
Heleno, Sandrina A.
https://www.ciencia-id.pt/8B18-3095-6FC9
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http://orcid.org/0000-0001-7224-1098
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Calhelha, Ricardo C.
Calhelha, Ricardo C.
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publishDate 2023
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spelling engMDPIpt_PTGrape agri-food wastes, such as skin, seeds, and other discarded by-products, contain phytochemical compounds that offer potential health benefits. Methods: This study aimed to investigate the polyphenol composition and bioactivities of different extracts obtained from grape marc and seeds, with the goal of exploring their potential for application as natural food additives. Results: Regardless of the extraction method used (dynamic maceration, ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE)), all extracts exhibited relatively high concentrations of phenolic compounds. The chemical characterization of the extracts revealed the presence of specific compounds and chemical groups associated with each extraction methodology. Moreover, the extracts displayed satisfactory antioxidant activities, especially in inhibiting lipoperoxidation as assessed by the TBARS assay. Additionally, the extracts demonstrated effective inhibition against different strains of bacteria and fungi known as food contaminants. Taken together, these findings indicate that those extracts have the potential to be tested as natural antioxidants and preservatives with sustainable origins in food and beverage systems. Among the extraction methods evaluated, traditional maceration and UAE provided extracts with the highest antioxidant and antimicrobial activities. Conclusions: Our results suggest the opportunity to explore grape marc and seeds discarded by the winery industry in Portugal as natural sources of bioactive compounds, which could be employed as functional food ingredients or technological additives. The valorization of grape biowastes offers a promising strategy to reduce waste and harness their potential health benefits.application/pdfpt_PTPolyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastesPersonalUeda, Jonata MassaoDSpacehttp://dspace.org/items/f98a1e3c-b52e-4997-b835-854c0e2a2c35DSpacehttp://dspace.org/items/f98a1e3c-b52e-4997-b835-854c0e2a2c35UedaJonata MassaoCiência IDhttps://www.ciencia-id.pt4417-F90B-68A3ORCIDhttp://orcid.org0000-0002-1452-3764Scopus Author IDhttps://www.scopus.com57222522617Griebler, Karoline RibeiroPersonalFinimundy, Tiane C.DSpacehttp://dspace.org/items/4f8767d4-4e62-4550-9b35-740cb2f672daDSpacehttp://dspace.org/items/4f8767d4-4e62-4550-9b35-740cb2f672daFinimundyTiane C.Ciência IDhttps://www.ciencia-id.pt2F18-67B1-776AORCIDhttp://orcid.org0000-0003-3516-0795PersonalRodrigues, Daniele BobrowskiDSpacehttp://dspace.org/items/18a661e9-0f77-4bd1-b2b0-5b929b760ab3DSpacehttp://dspace.org/items/18a661e9-0f77-4bd1-b2b0-5b929b760ab3RodriguesDaniele BobrowskiCiência IDhttps://www.ciencia-id.ptA91B-FE1D-B275ORCIDhttp://orcid.org0000-0003-0260-5751Verissimo, LaviniaPersonalPires, Tânia C.S.P.DSpacehttp://dspace.org/items/34af4d18-b8ae-4329-9450-69dc35ed448fDSpacehttp://dspace.org/items/34af4d18-b8ae-4329-9450-69dc35ed448fPiresTânia C.S.P.Ciência IDhttps://www.ciencia-id.pt321E-2D96-00CAORCIDhttp://orcid.org0000-0002-3954-3833Researcher IDhttps://www.researcherid.comQ-2842-2018Scopus Author IDhttps://www.scopus.com57057440000Gonçalves, João Carlos B.PersonalFernandes, Isabel P.DSpacehttp://dspace.org/items/aa1919bb-c35d-4abb-a137-10d998ad4ecaDSpacehttp://dspace.org/items/aa1919bb-c35d-4abb-a137-10d998ad4ecaFernandesIsabel P.Ciência IDhttps://www.ciencia-id.pt4D1C-441F-C7F0ORCIDhttp://orcid.org0000-0002-0069-4503Researcher IDhttps://www.researcherid.comL-1552-2016Scopus Author IDhttps://www.scopus.com26323585300PersonalPereira, ElianaDSpacehttp://dspace.org/items/dda60cdc-0a2a-4c10-863e-eaef1e6f1fb9DSpacehttp://dspace.org/items/dda60cdc-0a2a-4c10-863e-eaef1e6f1fb9PereiraElianaCiência IDhttps://www.ciencia-id.ptBE17-462D-9A75ORCIDhttp://orcid.org0000-0003-2854-6745Researcher IDhttps://www.researcherid.comQ-8017-2018Scopus Author IDhttps://www.scopus.com55938912300PersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801PersonalHeleno, Sandrina A.DSpacehttp://dspace.org/items/e89b5bf5-d315-49b6-871e-fa8eb6030676DSpacehttp://dspace.org/items/e89b5bf5-d315-49b6-871e-fa8eb6030676HelenoSandrina A.Ciência IDhttps://www.ciencia-id.pt8B18-3095-6FC9ORCIDhttp://orcid.org0000-0001-7224-1098Researcher IDhttps://www.researcherid.comL-5951-2014Scopus Author IDhttps://www.scopus.com30067731800PersonalCalhelha, Ricardo C.DSpacehttp://dspace.org/items/2d5d1a41-7561-4a01-871c-b4c97da35053DSpacehttp://dspace.org/items/2d5d1a41-7561-4a01-871c-b4c97da35053CalhelhaRicardo C.Ciência IDhttps://www.ciencia-id.ptF313-E3CE-554EORCIDhttp://orcid.org0000-0002-6801-4578Researcher IDhttps://www.researcherid.comJ-2172-2014Scopus Author IDhttps://www.scopus.com6507978333HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptDOIIsPartOf10.3390/molecules282173682023-12-18T09:52:46Z20232023-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/28957http://purl.org/coar/access_right/c_abf2open accessGrape marcBy-productsPhenolic compoundsAntioxidantAntimicrobial587916 bytesFundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaInnov2Eat: Innovative and powdered ready-to-eat dairy and vegetable-based yogurtsCrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal article2023http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/01d6f56d-d56e-49d4-bcc8-5fc14022e9f3/downloadMolecules
spellingShingle Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
Ueda, Jonata Massao
Grape marc
By-products
Phenolic compounds
Antioxidant
Antimicrobial
subject.fl_str_mv Grape marc
By-products
Phenolic compounds
Antioxidant
Antimicrobial
title Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
title_full Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
title_fullStr Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
title_full_unstemmed Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
title_short Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
title_sort Polyphenol composition by HPLC-DAD-(ESI-)MS/MS and bioactivities of extracts from grape agri-food wastes
topic Grape marc
By-products
Phenolic compounds
Antioxidant
Antimicrobial
topic_facet Grape marc
By-products
Phenolic compounds
Antioxidant
Antimicrobial
url http://hdl.handle.net/10198/28957
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