Publicação
Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
| Resumo: | The use of medicinal plants in a variety of health conditions remains essential for the discovery of new treatments. The present study aimed to investigate the bioactive properties of three native plants from Cabo Verde Islands, namely Artemisia gorgonum Webb, Sideroxylon marginatum (Decne. ex Webb) Cout., and Tamarix senegalensis DC., contributing to the characterization of less- known medicinal plants and their potential benefits for human health. Known compounds, such as kaempferol, quercetin, caffeyolquinic, and apigenin derivatives, among others, were detected in the plant species under study. Overall, all species demonstrated good antioxidant capacity, especially the ethanolic extracts of A. gorgonum (EC50 = 0.149 mg/mL) in TBARS assay. Moreover, the ethanolic extracts of the studied plants showed cytotoxic properties against tumor cells, and again the A. gorgonum extract proved to be the most effective in inhibiting tumor growth, mainly in the CaCO2 (GI50 = 17.3 μg/mL) and AGS (GI50 = 18.2 μg/mL) cell lines. Only the ethanolic extracts of T. senegalensis and S. marginatum demonstrated anti-inflammatory activity, albeit weak (EC50 = 35 and 43 μg/mL, respectively). The present study contributed to increased knowledge about the bioactive properties of these plants commonly used in traditional medicine, some of which was discussed for the first time, opening new perspectives for their use in a wider range of health conditions, especially in African countries, where access to modern health care is more limited. |
|---|---|
| Autores principais: | Essoh, Anyse P. |
| Outros Autores: | Liberal, Ângela; Fernandes, Ângela; Dias, Maria Inês; Pereira, Carla; Mandim, Filipa; Moldão-Martins, Margarida; Cravo, Pedro V.L.; Duarte, Maria Paula; Moura, Monica B.M.V.; Romeiras, Maria M.; Barros, Lillian |
| Assunto: | Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1867172952156405760 |
|---|---|
| author | Essoh, Anyse P. |
| author2 | Liberal, Ângela Fernandes, Ângela Dias, Maria Inês Pereira, Carla Mandim, Filipa Moldão-Martins, Margarida Cravo, Pedro V.L. Duarte, Maria Paula Moura, Monica B.M.V. Romeiras, Maria M. Barros, Lillian |
| author2_role | author author author author author author author author author author author |
| author_facet | Essoh, Anyse P. Liberal, Ângela Fernandes, Ângela Dias, Maria Inês Pereira, Carla Mandim, Filipa Moldão-Martins, Margarida Cravo, Pedro V.L. Duarte, Maria Paula Moura, Monica B.M.V. Romeiras, Maria M. Barros, Lillian |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Essoh, Anyse P.\"},{\"Person.name\":\"Liberal, Ângela\",\"Person.identifier.orcid\":\"0000-0002-9764-4894\"},{\"Person.name\":\"Fernandes, Ângela\",\"Person.identifier.orcid\":\"0000-0002-0157-9873\"},{\"Person.name\":\"Dias, Maria Inês\",\"Person.identifier.orcid\":\"0000-0001-8744-7814\"},{\"Person.name\":\"Pereira, Carla\",\"Person.identifier.orcid\":\"0000-0003-0093-771X\"},{\"Person.name\":\"Mandim, Filipa\",\"Person.identifier.orcid\":\"0000-0002-6494-2326\"},{\"Person.name\":\"Moldão-Martins, Margarida\"},{\"Person.name\":\"Cravo, Pedro V.L.\"},{\"Person.name\":\"Duarte, Maria Paula\"},{\"Person.name\":\"Moura, Monica B.M.V.\"},{\"Person.name\":\"Romeiras, Maria M.\"},{\"Person.name\":\"Barros, Lillian\",\"Person.identifier.orcid\":\"0000-0002-9050-5189\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Essoh, Anyse P. Liberal, Ângela Fernandes, Ângela Dias, Maria Inês Pereira, Carla Mandim, Filipa Moldão-Martins, Margarida Cravo, Pedro V.L. Duarte, Maria Paula Moura, Monica B.M.V. Romeiras, Maria M. Barros, Lillian |
| datacite.date.Accepted.fl_str_mv | 2022-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-08-03T11:04:23Z |
| datacite.date.embargoed.fl_str_mv | 2023-08-03T11:04:23Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| datacite.titles.title.fl_str_mv | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Essoh, Anyse P. Liberal, Ângela Fernandes, Ângela Dias, Maria Inês Pereira, Carla Mandim, Filipa Moldão-Martins, Margarida Cravo, Pedro V.L. Duarte, Maria Paula Moura, Monica B.M.V. Romeiras, Maria M. Barros, Lillian |
| dc.date.Accepted.fl_str_mv | 2022-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-08-03T11:04:23Z |
| dc.date.embargoed.fl_str_mv | 2023-08-03T11:04:23Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/28672 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | MDPI |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| dc.title.fl_str_mv | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The use of medicinal plants in a variety of health conditions remains essential for the discovery of new treatments. The present study aimed to investigate the bioactive properties of three native plants from Cabo Verde Islands, namely Artemisia gorgonum Webb, Sideroxylon marginatum (Decne. ex Webb) Cout., and Tamarix senegalensis DC., contributing to the characterization of less- known medicinal plants and their potential benefits for human health. Known compounds, such as kaempferol, quercetin, caffeyolquinic, and apigenin derivatives, among others, were detected in the plant species under study. Overall, all species demonstrated good antioxidant capacity, especially the ethanolic extracts of A. gorgonum (EC50 = 0.149 mg/mL) in TBARS assay. Moreover, the ethanolic extracts of the studied plants showed cytotoxic properties against tumor cells, and again the A. gorgonum extract proved to be the most effective in inhibiting tumor growth, mainly in the CaCO2 (GI50 = 17.3 μg/mL) and AGS (GI50 = 18.2 μg/mL) cell lines. Only the ethanolic extracts of T. senegalensis and S. marginatum demonstrated anti-inflammatory activity, albeit weak (EC50 = 35 and 43 μg/mL, respectively). The present study contributed to increased knowledge about the bioactive properties of these plants commonly used in traditional medicine, some of which was discussed for the first time, opening new perspectives for their use in a wider range of health conditions, especially in African countries, where access to modern health care is more limited. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://bibliotecadigital.ipb.pt/bitstreams/ce01d15e-22c0-4241-93c6-9b9b46d35444/download |
| funding.funder.alternateName_str_mv | FCT FCT |
| funding.funder.identifier_str_mv | http://doi.org/10.13039/501100001871 http://doi.org/10.13039/501100001871 |
| funding.funder.name_str_mv | Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia |
| funding.name_str_mv | 6817 - DCRRNI ID 6817 - DCRRNI ID |
| id | ipb_424f85bf34be524168f0a678fdb07cd0 |
| identifier.url.fl_str_mv | http://hdl.handle.net/10198/28672 |
| instacron_str | ipb |
| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
| network_acronym_str | ipb |
| network_name_str | Biblioteca Digital do IPB |
| oai_identifier_str | oai:bibliotecadigital.ipb.pt:10198/28672 |
| organization_str_mv | urn:organizationAcronym:ipb |
| person_str_mv | Essoh, Anyse P. Liberal, Ângela Liberal, Ângela https://www.ciencia-id.pt/741E-B12D-9EB1 741E-B12D-9EB1 http://orcid.org/0000-0002-9764-4894 0000-0002-9764-4894 Fernandes, Ângela Fernandes, Ângela https://www.ciencia-id.pt/2015-0434-AE7C 2015-0434-AE7C http://orcid.org/0000-0002-0157-9873 0000-0002-0157-9873 Dias, Maria Inês Dias, Maria Inês https://www.ciencia-id.pt/2A13-4BE6-C7CF 2A13-4BE6-C7CF http://orcid.org/0000-0001-8744-7814 0000-0001-8744-7814 Pereira, Carla Pereira, Carla https://www.ciencia-id.pt/EF10-2739-2B70 EF10-2739-2B70 http://orcid.org/0000-0003-0093-771X 0000-0003-0093-771X Mandim, Filipa Mandim, Filipa https://www.ciencia-id.pt/F318-9049-EB99 F318-9049-EB99 http://orcid.org/0000-0002-6494-2326 0000-0002-6494-2326 Moldão-Martins, Margarida Cravo, Pedro V.L. Duarte, Maria Paula Moura, Monica B.M.V. Romeiras, Maria M. Barros, Lillian Barros, Lillian https://www.ciencia-id.pt/9616-35CB-D001 9616-35CB-D001 http://orcid.org/0000-0002-9050-5189 0000-0002-9050-5189 |
| publishDate | 2022 |
| publisher.none.fl_str_mv | MDPI |
| reponame_str | Biblioteca Digital do IPB |
| repository_id_str | urn:repositoryAcronym:ipb |
| service_str_mv | urn:repositoryAcronym:ipb |
| spelling | engMDPIpt_PTThe use of medicinal plants in a variety of health conditions remains essential for the discovery of new treatments. The present study aimed to investigate the bioactive properties of three native plants from Cabo Verde Islands, namely Artemisia gorgonum Webb, Sideroxylon marginatum (Decne. ex Webb) Cout., and Tamarix senegalensis DC., contributing to the characterization of less- known medicinal plants and their potential benefits for human health. Known compounds, such as kaempferol, quercetin, caffeyolquinic, and apigenin derivatives, among others, were detected in the plant species under study. Overall, all species demonstrated good antioxidant capacity, especially the ethanolic extracts of A. gorgonum (EC50 = 0.149 mg/mL) in TBARS assay. Moreover, the ethanolic extracts of the studied plants showed cytotoxic properties against tumor cells, and again the A. gorgonum extract proved to be the most effective in inhibiting tumor growth, mainly in the CaCO2 (GI50 = 17.3 μg/mL) and AGS (GI50 = 18.2 μg/mL) cell lines. Only the ethanolic extracts of T. senegalensis and S. marginatum demonstrated anti-inflammatory activity, albeit weak (EC50 = 35 and 43 μg/mL, respectively). The present study contributed to increased knowledge about the bioactive properties of these plants commonly used in traditional medicine, some of which was discussed for the first time, opening new perspectives for their use in a wider range of health conditions, especially in African countries, where access to modern health care is more limited.application/pdfpt_PTEvaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal PlantsEssoh, Anyse P.PersonalLiberal, ÂngelaDSpacehttp://dspace.org/items/b5aa6848-62a1-43fb-9fa8-2139031462c3DSpacehttp://dspace.org/items/b5aa6848-62a1-43fb-9fa8-2139031462c3LiberalÂngelaCiência IDhttps://www.ciencia-id.pt741E-B12D-9EB1ORCIDhttp://orcid.org0000-0002-9764-4894PersonalFernandes, ÂngelaDSpacehttp://dspace.org/items/6233e657-3885-40a3-885e-0d51cf4dbaadDSpacehttp://dspace.org/items/6233e657-3885-40a3-885e-0d51cf4dbaadFernandesÂngelaCiência IDhttps://www.ciencia-id.pt2015-0434-AE7CORCIDhttp://orcid.org0000-0002-0157-9873PersonalDias, Maria InêsDSpacehttp://dspace.org/items/7ca8432b-e7f4-4116-a56e-9eba0d4403bdDSpacehttp://dspace.org/items/7ca8432b-e7f4-4116-a56e-9eba0d4403bdDiasMaria InêsCiência IDhttps://www.ciencia-id.pt2A13-4BE6-C7CFORCIDhttp://orcid.org0000-0001-8744-7814Researcher IDhttps://www.researcherid.comM-8242-2013Scopus Author IDhttps://www.scopus.com54388787000PersonalPereira, CarlaDSpacehttp://dspace.org/items/e07a8e12-52bb-47c5-bae7-41a5f648213bDSpacehttp://dspace.org/items/e07a8e12-52bb-47c5-bae7-41a5f648213bPereiraCarlaCiência IDhttps://www.ciencia-id.ptEF10-2739-2B70ORCIDhttp://orcid.org0000-0003-0093-771XResearcher IDhttps://www.researcherid.comK-1629-2016Scopus Author IDhttps://www.scopus.com55627876424PersonalMandim, FilipaDSpacehttp://dspace.org/items/bcc274d4-7e6c-46a8-8e49-2752f9dbfbcdDSpacehttp://dspace.org/items/bcc274d4-7e6c-46a8-8e49-2752f9dbfbcdMandimFilipaCiência IDhttps://www.ciencia-id.ptF318-9049-EB99ORCIDhttp://orcid.org0000-0002-6494-2326Moldão-Martins, MargaridaCravo, Pedro V.L.Duarte, Maria PaulaMoura, Monica B.M.V.Romeiras, Maria M.PersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf1424-8247DOIIsPartOf10.3390/ph150911622023-08-03T11:04:23Z20222022-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/28672http://purl.org/coar/access_right/c_abf2open accessBioactive propertiesCabo VerdeEndemic medicinal plantsTraditional medicine344955 bytesFundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal article2022http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/ce01d15e-22c0-4241-93c6-9b9b46d35444/downloadPharmaceuticals1591162 |
| spellingShingle | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants Essoh, Anyse P. Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| status | SINGLETON |
| subject.fl_str_mv | Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| title | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| title_full | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| title_fullStr | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| title_full_unstemmed | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| title_short | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| title_sort | Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants |
| topic | Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| topic_facet | Bioactive properties Cabo Verde Endemic medicinal plants Traditional medicine |
| url | http://hdl.handle.net/10198/28672 |
| visible | 1 |