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Solubility of hesperetin in mixed solvents

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Resumo:The study of the solubility of important biomolecules such as flavonoids is essential to support the design of several separation processes in the food and pharmaceutical industries. Following our previous studies, new solubility data of hesperetin in the mixed solvents water + acetone, water + ethanol, and water + methanol were measured, at 298.2 K, by the isothermal shake-flask method. The results obtained show three solid−liquid phase diagrams with distinct features. Additionally, the solid crystals obtained from the solubility studies were analyzed by powder X-ray diffraction, infrared spectroscopy, and thermogravimetric analysis indicating that, depending on the mixed solvents composition, two different crystal structures of hesperetin, already described in the literature, can be obtained, corresponding either to the anhydrous or the monohydrate forms.
Autores principais:Ferreira, Olga
Outros Autores:Schröder, Bernd; Pinho, Simão
Ano:2013
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Ferreira, Olga
author2 Schröder, Bernd
Pinho, Simão
author2_role author
author
author_facet Ferreira, Olga
Schröder, Bernd
Pinho, Simão
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Ferreira, Olga\",\"Person.identifier.orcid\":\"0000-0001-8414-3479\"},{\"Person.name\":\"Schröder, Bernd\"},{\"Person.name\":\"Pinho, Simão\",\"Person.identifier.orcid\":\"0000-0002-9211-857X\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Ferreira, Olga
Schröder, Bernd
Pinho, Simão
datacite.date.Accepted.fl_str_mv 2013-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2014-02-10T14:09:49Z
datacite.date.embargoed.fl_str_mv 2014-02-10T14:09:49Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.titles.title.fl_str_mv Solubility of hesperetin in mixed solvents
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Ferreira, Olga
Schröder, Bernd
Pinho, Simão
dc.date.Accepted.fl_str_mv 2013-01-01T00:00:00Z
dc.date.available.fl_str_mv 2014-02-10T14:09:49Z
dc.date.embargoed.fl_str_mv 2014-02-10T14:09:49Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/9298
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv American Chemical Society
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.title.fl_str_mv Solubility of hesperetin in mixed solvents
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description The study of the solubility of important biomolecules such as flavonoids is essential to support the design of several separation processes in the food and pharmaceutical industries. Following our previous studies, new solubility data of hesperetin in the mixed solvents water + acetone, water + ethanol, and water + methanol were measured, at 298.2 K, by the isothermal shake-flask method. The results obtained show three solid−liquid phase diagrams with distinct features. Additionally, the solid crystals obtained from the solubility studies were analyzed by powder X-ray diffraction, infrared spectroscopy, and thermogravimetric analysis indicating that, depending on the mixed solvents composition, two different crystal structures of hesperetin, already described in the literature, can be obtained, corresponding either to the anhydrous or the monohydrate forms.
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eu_rights_str_mv restrictedAccess
format article
fulltext.url.fl_str_mv https://bibliotecadigital.ipb.pt/bitstreams/852bed5f-182f-4521-bbf1-5a395268aaee/download
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identifier.url.fl_str_mv http://hdl.handle.net/10198/9298
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institution Instituto Politécnico de Bragança
instname_str Instituto Politécnico de Bragança
language eng
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oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/9298
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Ferreira, Olga
Ferreira, Olga
https://www.ciencia-id.pt/9F1D-C75A-4A54
9F1D-C75A-4A54
http://orcid.org/0000-0001-8414-3479
0000-0001-8414-3479
Schröder, Bernd
Pinho, Simão
Pinho, Simão
https://www.ciencia-id.pt/481D-73AD-8D0F
481D-73AD-8D0F
http://orcid.org/0000-0002-9211-857X
0000-0002-9211-857X
publishDate 2013
publisher.none.fl_str_mv American Chemical Society
reponame_str Biblioteca Digital do IPB
repository_id_str urn:repositoryAcronym:ipb
service_str_mv urn:repositoryAcronym:ipb
spelling engAmerican Chemical SocietyporThe study of the solubility of important biomolecules such as flavonoids is essential to support the design of several separation processes in the food and pharmaceutical industries. Following our previous studies, new solubility data of hesperetin in the mixed solvents water + acetone, water + ethanol, and water + methanol were measured, at 298.2 K, by the isothermal shake-flask method. The results obtained show three solid−liquid phase diagrams with distinct features. Additionally, the solid crystals obtained from the solubility studies were analyzed by powder X-ray diffraction, infrared spectroscopy, and thermogravimetric analysis indicating that, depending on the mixed solvents composition, two different crystal structures of hesperetin, already described in the literature, can be obtained, corresponding either to the anhydrous or the monohydrate forms.application/pdfporSolubility of hesperetin in mixed solventsPersonalFerreira, OlgaDSpacehttp://dspace.org/items/59e0c608-0c21-4191-af5e-529d21970399DSpacehttp://dspace.org/items/59e0c608-0c21-4191-af5e-529d21970399FerreiraOlgaCiência IDhttps://www.ciencia-id.pt9F1D-C75A-4A54ORCIDhttp://orcid.org0000-0001-8414-3479Researcher IDhttps://www.researcherid.comM-4567-2013Scopus Author IDhttps://www.scopus.com57203083219Schröder, BerndPersonalPinho, SimãoDSpacehttp://dspace.org/items/8ef7789a-34f3-4915-a666-4efe26272a30DSpacehttp://dspace.org/items/8ef7789a-34f3-4915-a666-4efe26272a30PinhoSimãoCiência IDhttps://www.ciencia-id.pt481D-73AD-8D0FORCIDhttp://orcid.org0000-0002-9211-857XResearcher IDhttps://www.researcherid.comD-4148-2013Scopus Author IDhttps://www.scopus.com7003570175HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf0021-95682014-02-10T14:09:49Z20132013-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/9298http://purl.org/coar/access_right/c_16ecrestricted access858252 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/852bed5f-182f-4521-bbf1-5a395268aaee/downloadJ. Chem. Eng. Data5826162621
spellingShingle Solubility of hesperetin in mixed solvents
Ferreira, Olga
status SINGLETON
title Solubility of hesperetin in mixed solvents
title_full Solubility of hesperetin in mixed solvents
title_fullStr Solubility of hesperetin in mixed solvents
title_full_unstemmed Solubility of hesperetin in mixed solvents
title_short Solubility of hesperetin in mixed solvents
title_sort Solubility of hesperetin in mixed solvents
url http://hdl.handle.net/10198/9298
visible 1