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Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice

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Resumo:This work evaluated the effects of the consumption of a plant-based beverage (Cyperus esculentus L., Adansonia digitata L., and thermal water) on the physiological parameters of mice over a 28-day period. Thirty-two female FVB/n mice (n = 8) were randomly assigned to one of four groups divided into two experimental protocols: Group 1 drank water and Group 2 drank a plant-based beverage for 24 h; in the second experimental protocol, Group 3 consumed water and Group 4 consumed plant-based beverage for a limited time (4 h). Two experimental protocols were conducted to assess whether the exposure time to the beverage affects the animals’ physiological parameters, to determine if there is a possible daily limit for consumption of the product and to analyze their adverse effects. The mice consuming a beverage ingested a larger amount of drink and a smaller amount of food. Histologically there are no pathological changes in collected organs. The consumption of a plant-based beverage has been shown to have a positive effect on oxidative markers and can have a diuretic action. According to results, no behavioral changes or clinical signs of disease were observed throughout both experimental protocols, and no mortality was recorded.
Autores principais:Fernandes, Filipa Alexandra
Outros Autores:Oliveira, Paula A.; Pinto, M.L.; Venâncio, Carlos; Félix, Luís; Medeiros-Fonseca, Beatriz; Correia, Rossana; Prieto Lage, Miguel A.; Ferreira, Isabel C.F.R.; Barros, Lillian; Heleno, Sandrina A.
Assunto:Plant-based beverage Cyperus esculentus L. In vivo safety assessment FVB/N
Ano:2024
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Fernandes, Filipa Alexandra
author2 Oliveira, Paula A.
Pinto, M.L.
Venâncio, Carlos
Félix, Luís
Medeiros-Fonseca, Beatriz
Correia, Rossana
Prieto Lage, Miguel A.
Ferreira, Isabel C.F.R.
Barros, Lillian
Heleno, Sandrina A.
author2_role author
author
author
author
author
author
author
author
author
author
author_facet Fernandes, Filipa Alexandra
Oliveira, Paula A.
Pinto, M.L.
Venâncio, Carlos
Félix, Luís
Medeiros-Fonseca, Beatriz
Correia, Rossana
Prieto Lage, Miguel A.
Ferreira, Isabel C.F.R.
Barros, Lillian
Heleno, Sandrina A.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Fernandes, Filipa Alexandra\",\"Person.identifier.orcid\":\"0000-0001-6807-1137\"},{\"Person.name\":\"Oliveira, Paula A.\"},{\"Person.name\":\"Pinto, M.L.\"},{\"Person.name\":\"Venâncio, Carlos\"},{\"Person.name\":\"Félix, Luís\"},{\"Person.name\":\"Medeiros-Fonseca, Beatriz\"},{\"Person.name\":\"Correia, Rossana\"},{\"Person.name\":\"Prieto Lage, Miguel A.\"},{\"Person.name\":\"Ferreira, Isabel C.F.R.\",\"Person.identifier.orcid\":\"0000-0003-4910-4882\"},{\"Person.name\":\"Barros, Lillian\",\"Person.identifier.orcid\":\"0000-0002-9050-5189\"},{\"Person.name\":\"Heleno, Sandrina A.\",\"Person.identifier.orcid\":\"0000-0001-7224-1098\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Fernandes, Filipa Alexandra
Oliveira, Paula A.
Pinto, M.L.
Venâncio, Carlos
Félix, Luís
Medeiros-Fonseca, Beatriz
Correia, Rossana
Prieto Lage, Miguel A.
Ferreira, Isabel C.F.R.
Barros, Lillian
Heleno, Sandrina A.
datacite.date.Accepted.fl_str_mv 2024-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2024-12-20T16:30:04Z
datacite.date.embargoed.fl_str_mv 2024-12-20T16:30:04Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Plant-based beverage
Cyperus esculentus L.
In vivo safety assessment
FVB/N
datacite.titles.title.fl_str_mv Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Fernandes, Filipa Alexandra
Oliveira, Paula A.
Pinto, M.L.
Venâncio, Carlos
Félix, Luís
Medeiros-Fonseca, Beatriz
Correia, Rossana
Prieto Lage, Miguel A.
Ferreira, Isabel C.F.R.
Barros, Lillian
Heleno, Sandrina A.
dc.date.Accepted.fl_str_mv 2024-01-01T00:00:00Z
dc.date.available.fl_str_mv 2024-12-20T16:30:04Z
dc.date.embargoed.fl_str_mv 2024-12-20T16:30:04Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/30770
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Plant-based beverage
Cyperus esculentus L.
In vivo safety assessment
FVB/N
dc.title.fl_str_mv Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description This work evaluated the effects of the consumption of a plant-based beverage (Cyperus esculentus L., Adansonia digitata L., and thermal water) on the physiological parameters of mice over a 28-day period. Thirty-two female FVB/n mice (n = 8) were randomly assigned to one of four groups divided into two experimental protocols: Group 1 drank water and Group 2 drank a plant-based beverage for 24 h; in the second experimental protocol, Group 3 consumed water and Group 4 consumed plant-based beverage for a limited time (4 h). Two experimental protocols were conducted to assess whether the exposure time to the beverage affects the animals’ physiological parameters, to determine if there is a possible daily limit for consumption of the product and to analyze their adverse effects. The mice consuming a beverage ingested a larger amount of drink and a smaller amount of food. Histologically there are no pathological changes in collected organs. The consumption of a plant-based beverage has been shown to have a positive effect on oxidative markers and can have a diuretic action. According to results, no behavioral changes or clinical signs of disease were observed throughout both experimental protocols, and no mortality was recorded.
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http://doi.org/10.13039/501100001871
funding.funder.name_str_mv Fundação para a Ciência e a Tecnologia
Fundação para a Ciência e a Tecnologia
Fundação para a Ciência e a Tecnologia
Fundação para a Ciência e a Tecnologia
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funding.name_str_mv 6817 - DCRRNI ID
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UIDB/04033/2020
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04033%2F2020/PT
SFRH/BD/145467/2019
info:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F145467%2F2019/PT
id ipb_47c24c385e096f6dbe2e8bd4ffefb549
identifier.url.fl_str_mv http://hdl.handle.net/10198/30770
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instname_str Instituto Politécnico de Bragança
language eng
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network_name_str Biblioteca Digital do IPB
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/30770
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Fernandes, Filipa Alexandra
Fernandes, Filipa Alexandra
https://www.ciencia-id.pt/2A1F-9985-F38B
2A1F-9985-F38B
http://orcid.org/0000-0001-6807-1137
0000-0001-6807-1137
Oliveira, Paula A.
Pinto, M.L.
Venâncio, Carlos
Félix, Luís
Medeiros-Fonseca, Beatriz
Correia, Rossana
Prieto Lage, Miguel A.
Ferreira, Isabel C.F.R.
Ferreira, Isabel C.F.R.
https://www.ciencia-id.pt/9418-CF95-9919
9418-CF95-9919
http://orcid.org/0000-0003-4910-4882
0000-0003-4910-4882
Barros, Lillian
Barros, Lillian
https://www.ciencia-id.pt/9616-35CB-D001
9616-35CB-D001
http://orcid.org/0000-0002-9050-5189
0000-0002-9050-5189
Heleno, Sandrina A.
Heleno, Sandrina A.
https://www.ciencia-id.pt/8B18-3095-6FC9
8B18-3095-6FC9
http://orcid.org/0000-0001-7224-1098
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publishDate 2024
publisher.none.fl_str_mv Elsevier
reponame_str Biblioteca Digital do IPB
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spelling engElsevierpt_PTThis work evaluated the effects of the consumption of a plant-based beverage (Cyperus esculentus L., Adansonia digitata L., and thermal water) on the physiological parameters of mice over a 28-day period. Thirty-two female FVB/n mice (n = 8) were randomly assigned to one of four groups divided into two experimental protocols: Group 1 drank water and Group 2 drank a plant-based beverage for 24 h; in the second experimental protocol, Group 3 consumed water and Group 4 consumed plant-based beverage for a limited time (4 h). Two experimental protocols were conducted to assess whether the exposure time to the beverage affects the animals’ physiological parameters, to determine if there is a possible daily limit for consumption of the product and to analyze their adverse effects. The mice consuming a beverage ingested a larger amount of drink and a smaller amount of food. Histologically there are no pathological changes in collected organs. The consumption of a plant-based beverage has been shown to have a positive effect on oxidative markers and can have a diuretic action. According to results, no behavioral changes or clinical signs of disease were observed throughout both experimental protocols, and no mortality was recorded.application/pdfpt_PTEffects of a Cyperus esculentus L. plant-based beverage on FVB/n female micePersonalFernandes, Filipa AlexandraDSpacehttp://dspace.org/items/95f2a15c-591c-44b9-bcc3-dfdf49c6af26DSpacehttp://dspace.org/items/95f2a15c-591c-44b9-bcc3-dfdf49c6af26FernandesFilipa AlexandraCiência IDhttps://www.ciencia-id.pt2A1F-9985-F38BORCIDhttp://orcid.org0000-0001-6807-1137Researcher IDhttps://www.researcherid.comA-8045-2019Oliveira, Paula A.Pinto, M.L.Venâncio, CarlosFélix, LuísMedeiros-Fonseca, BeatrizCorreia, RossanaPrieto Lage, Miguel A.PersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600PersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801PersonalHeleno, Sandrina A.DSpacehttp://dspace.org/items/e89b5bf5-d315-49b6-871e-fa8eb6030676DSpacehttp://dspace.org/items/e89b5bf5-d315-49b6-871e-fa8eb6030676HelenoSandrina A.Ciência IDhttps://www.ciencia-id.pt8B18-3095-6FC9ORCIDhttp://orcid.org0000-0001-7224-1098Researcher IDhttps://www.researcherid.comL-5951-2014Scopus Author IDhttps://www.scopus.com30067731800HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf0278-6915DOIIsPartOf10.1016/j.fct.2024.1150822024-12-20T16:30:04Z20242024-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/30770http://purl.org/coar/access_right/c_16ecrestricted accessPlant-based beverageCyperus esculentus L.In vivo safety assessmentFVB/N4396048 bytesFundação para a Ciência e a TecnologiaMountain Research Centerinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00690%2F2020/PTUIDB/00690/20206817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaMountain Research Centerinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F00690%2F2020/PTUIDP/00690/20206817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaAssociate Laboratory for Sustainability and Tecnology in Mountain Regionsinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA%2FP%2F0007%2F2020/PTLA/P/0007/20206817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaCentre for the Research and Technology of Agro-Environmental and Biological Sciencesinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04033%2F2020/PTUIDB/04033/20206817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaDevelopment of nutraceuticals and functional foods with natural preservative and bioactive ingredientsinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F145467%2F2019/PTSFRH/BD/145467/2019Crossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal article2024http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/822f4fda-a125-40d0-a330-4e2bebce8b9e/downloadFood and Chemical Toxicology194110
spellingShingle Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
Fernandes, Filipa Alexandra
Plant-based beverage
Cyperus esculentus L.
In vivo safety assessment
FVB/N
status SINGLETON
subject.fl_str_mv Plant-based beverage
Cyperus esculentus L.
In vivo safety assessment
FVB/N
title Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
title_full Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
title_fullStr Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
title_full_unstemmed Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
title_short Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
title_sort Effects of a Cyperus esculentus L. plant-based beverage on FVB/n female mice
topic Plant-based beverage
Cyperus esculentus L.
In vivo safety assessment
FVB/N
topic_facet Plant-based beverage
Cyperus esculentus L.
In vivo safety assessment
FVB/N
url http://hdl.handle.net/10198/30770
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