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Synthesis and transformation of halochromones

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Resumo:Chromones (4H-1-benzopyran-4-ones) are one of the most abundant groups of naturally occurring oxygen containing heterocyclic compounds possessing a benzo-γ-pyrone framework, 1a. The significance of these widely spread and highly diverse compounds is far beyond the important biological functions they assume in nature [1, 2]. Natural and synthetic chromone derivatives have been assigned as lead structures in drug development with some already being marketed [3]. The majority of the naturally occurring chromones are 2- and 3-aryl derivatives, called flavones 1b and isoflavones 1c, respectively. However, other types of chromones have also been found in the plant kingdom, such as 3-methylchromones 1d and 2- styrylchromones 1e (Fig. 1).
Autores principais:Tomé, Sara M.
Outros Autores:Silva, Artur; Santos, Clementina M.M.
Assunto:Chromones Cross-coupling reactions Halochromones Halogenation Reactivity Synthesis
Ano:2014
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Tomé, Sara M.
author2 Silva, Artur
Santos, Clementina M.M.
author2_role author
author
author_facet Tomé, Sara M.
Silva, Artur
Santos, Clementina M.M.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Tomé, Sara M.\"},{\"Person.name\":\"Silva, Artur\"},{\"Person.name\":\"Santos, Clementina M.M.\",\"Person.identifier.orcid\":\"0000-0003-4380-7990\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Tomé, Sara M.
Silva, Artur
Santos, Clementina M.M.
datacite.date.Accepted.fl_str_mv 2014-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2015-03-02T10:31:20Z
datacite.date.embargoed.fl_str_mv 2015-03-02T10:31:20Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Chromones
Cross-coupling reactions
Halochromones
Halogenation
Reactivity
Synthesis
datacite.titles.title.fl_str_mv Synthesis and transformation of halochromones
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Tomé, Sara M.
Silva, Artur
Santos, Clementina M.M.
dc.date.Accepted.fl_str_mv 2014-01-01T00:00:00Z
dc.date.available.fl_str_mv 2015-03-02T10:31:20Z
dc.date.embargoed.fl_str_mv 2015-03-02T10:31:20Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/11714
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Bentham Science
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Chromones
Cross-coupling reactions
Halochromones
Halogenation
Reactivity
Synthesis
dc.title.fl_str_mv Synthesis and transformation of halochromones
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Chromones (4H-1-benzopyran-4-ones) are one of the most abundant groups of naturally occurring oxygen containing heterocyclic compounds possessing a benzo-γ-pyrone framework, 1a. The significance of these widely spread and highly diverse compounds is far beyond the important biological functions they assume in nature [1, 2]. Natural and synthetic chromone derivatives have been assigned as lead structures in drug development with some already being marketed [3]. The majority of the naturally occurring chromones are 2- and 3-aryl derivatives, called flavones 1b and isoflavones 1c, respectively. However, other types of chromones have also been found in the plant kingdom, such as 3-methylchromones 1d and 2- styrylchromones 1e (Fig. 1).
dirty 0
eu_rights_str_mv openAccess
format article
fulltext.url.fl_str_mv https://bibliotecadigital.ipb.pt/bitstreams/07121627-2352-4602-867f-10a1f16a8959/download
id ipb_4835f53c8aee8da8bae7ee2044e2fc0b
identifier.url.fl_str_mv http://hdl.handle.net/10198/11714
instacron_str ipb
institution Instituto Politécnico de Bragança
instname_str Instituto Politécnico de Bragança
language eng
network_acronym_str ipb
network_name_str Biblioteca Digital do IPB
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/11714
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Tomé, Sara M.
Silva, Artur
Santos, Clementina M.M.
Santos, Clementina M.M.
https://www.ciencia-id.pt/9018-DB9C-C590
9018-DB9C-C590
http://orcid.org/0000-0003-4380-7990
0000-0003-4380-7990
publishDate 2014
publisher.none.fl_str_mv Bentham Science
reponame_str Biblioteca Digital do IPB
repository_id_str urn:repositoryAcronym:ipb
service_str_mv urn:repositoryAcronym:ipb
spelling engBentham ScienceporChromones (4H-1-benzopyran-4-ones) are one of the most abundant groups of naturally occurring oxygen containing heterocyclic compounds possessing a benzo-γ-pyrone framework, 1a. The significance of these widely spread and highly diverse compounds is far beyond the important biological functions they assume in nature [1, 2]. Natural and synthetic chromone derivatives have been assigned as lead structures in drug development with some already being marketed [3]. The majority of the naturally occurring chromones are 2- and 3-aryl derivatives, called flavones 1b and isoflavones 1c, respectively. However, other types of chromones have also been found in the plant kingdom, such as 3-methylchromones 1d and 2- styrylchromones 1e (Fig. 1).application/pdfporSynthesis and transformation of halochromonesTomé, Sara M.Silva, ArturPersonalSantos, Clementina M.M.DSpacehttp://dspace.org/items/64f662b6-775d-4ea0-bfd7-f527af0ac1a0DSpacehttp://dspace.org/items/64f662b6-775d-4ea0-bfd7-f527af0ac1a0SantosClementina M.M.Ciência IDhttps://www.ciencia-id.pt9018-DB9C-C590ORCIDhttp://orcid.org0000-0003-4380-7990Scopus Author IDhttps://www.scopus.com7201458663HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf1570-1794DOIIsPartOf10.2174/157017941131099900632015-03-02T10:31:20Z20142014-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/11714http://purl.org/coar/access_right/c_abf2open accessChromonesCross-coupling reactionsHalochromonesHalogenationReactivitySynthesis610661 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/07121627-2352-4602-867f-10a1f16a8959/downloadCurr. Org. Synth.11317341
spellingShingle Synthesis and transformation of halochromones
Tomé, Sara M.
Chromones
Cross-coupling reactions
Halochromones
Halogenation
Reactivity
Synthesis
status SINGLETON
subject.fl_str_mv Chromones
Cross-coupling reactions
Halochromones
Halogenation
Reactivity
Synthesis
title Synthesis and transformation of halochromones
title_full Synthesis and transformation of halochromones
title_fullStr Synthesis and transformation of halochromones
title_full_unstemmed Synthesis and transformation of halochromones
title_short Synthesis and transformation of halochromones
title_sort Synthesis and transformation of halochromones
topic Chromones
Cross-coupling reactions
Halochromones
Halogenation
Reactivity
Synthesis
topic_facet Chromones
Cross-coupling reactions
Halochromones
Halogenation
Reactivity
Synthesis
url http://hdl.handle.net/10198/11714
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