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Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007

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Resumo:Ochratoxin A (OTA) is a mycotoxin produced by fungi such as Penicillium verrucosum and Aspergillium spp. and has been found to have a variety of potentially deadly toxic effects. The favoured substrate for fungal growth and OTA production appears to be cereals and flour-based products, including bread. Due to the dietary relevance of bread for the Portuguese population, it is imperative that its OTA content remains well within safe quantities. As such, bread samples collected from commercial surfaces across the Algarve region and from the city of Bragança during the winter of 2007 were tested for OTA through extraction with immunoaffinity columns and quantification by liquid chromatography coupled with fluorescence detection. Although OTA content was found to be above the limit of quantification in approximately 60% and 50% of the analysed samples from Algarve and Bragança, respectively, all samples were found to be compliant with European Commission. OTA content reached maximums of 0.49 ng/g in Algarve and 0.43 ng/g in Bragança, and was thus below the maximum limit established by European legislation for bread of 3 ng/g. The results of the present study put the estimated daily intake of OTA from bread at approximately 0.26 ng/kg bw/day in Algarve and 0.38 ng/kg bw/day in Bragança, circa 1.5% and 2.0% of the TDI established by either the EFSA or the FAO/WHO, or over 4.5% and 6.5% if we consider the FAO/WHO advised bread consumption of 250 g/day. These results seem to suggest that, in these two Portuguese regions, OTA contamination is well under control and unlikely to represent a threat to consumer health.
Autores principais:Bento, J.M.V.
Outros Autores:Pena, A.; Lino, C.M.; Pereira, J.A.
Assunto:Ochratoxin A Wheat bread EDI Algarve Bragança
Ano:2009
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Bento, J.M.V.
author2 Pena, A.
Lino, C.M.
Pereira, J.A.
author2_role author
author
author
author_facet Bento, J.M.V.
Pena, A.
Lino, C.M.
Pereira, J.A.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Bento, J.M.V.\"},{\"Person.name\":\"Pena, A.\"},{\"Person.name\":\"Lino, C.M.\"},{\"Person.name\":\"Pereira, J.A.\",\"Person.identifier.orcid\":\"0000-0002-2260-0600\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Bento, J.M.V.
Pena, A.
Lino, C.M.
Pereira, J.A.
datacite.date.Accepted.fl_str_mv 2009-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2011-01-10T15:41:52Z
datacite.date.embargoed.fl_str_mv 2011-01-10T15:41:52Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Ochratoxin A
Wheat bread
EDI
Algarve
Bragança
datacite.titles.title.fl_str_mv Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Bento, J.M.V.
Pena, A.
Lino, C.M.
Pereira, J.A.
dc.date.Accepted.fl_str_mv 2009-01-01T00:00:00Z
dc.date.available.fl_str_mv 2011-01-10T15:41:52Z
dc.date.embargoed.fl_str_mv 2011-01-10T15:41:52Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/3042
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Ochratoxin A
Wheat bread
EDI
Algarve
Bragança
dc.title.fl_str_mv Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Ochratoxin A (OTA) is a mycotoxin produced by fungi such as Penicillium verrucosum and Aspergillium spp. and has been found to have a variety of potentially deadly toxic effects. The favoured substrate for fungal growth and OTA production appears to be cereals and flour-based products, including bread. Due to the dietary relevance of bread for the Portuguese population, it is imperative that its OTA content remains well within safe quantities. As such, bread samples collected from commercial surfaces across the Algarve region and from the city of Bragança during the winter of 2007 were tested for OTA through extraction with immunoaffinity columns and quantification by liquid chromatography coupled with fluorescence detection. Although OTA content was found to be above the limit of quantification in approximately 60% and 50% of the analysed samples from Algarve and Bragança, respectively, all samples were found to be compliant with European Commission. OTA content reached maximums of 0.49 ng/g in Algarve and 0.43 ng/g in Bragança, and was thus below the maximum limit established by European legislation for bread of 3 ng/g. The results of the present study put the estimated daily intake of OTA from bread at approximately 0.26 ng/kg bw/day in Algarve and 0.38 ng/kg bw/day in Bragança, circa 1.5% and 2.0% of the TDI established by either the EFSA or the FAO/WHO, or over 4.5% and 6.5% if we consider the FAO/WHO advised bread consumption of 250 g/day. These results seem to suggest that, in these two Portuguese regions, OTA contamination is well under control and unlikely to represent a threat to consumer health.
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organization_str_mv urn:organizationAcronym:ipb
person_str_mv Bento, J.M.V.
Pena, A.
Lino, C.M.
Pereira, J.A.
Pereira, J.A.
https://www.ciencia-id.pt/611F-80B2-A7C1
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publishDate 2009
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spelling engElsevierporOchratoxin A (OTA) is a mycotoxin produced by fungi such as Penicillium verrucosum and Aspergillium spp. and has been found to have a variety of potentially deadly toxic effects. The favoured substrate for fungal growth and OTA production appears to be cereals and flour-based products, including bread. Due to the dietary relevance of bread for the Portuguese population, it is imperative that its OTA content remains well within safe quantities. As such, bread samples collected from commercial surfaces across the Algarve region and from the city of Bragança during the winter of 2007 were tested for OTA through extraction with immunoaffinity columns and quantification by liquid chromatography coupled with fluorescence detection. Although OTA content was found to be above the limit of quantification in approximately 60% and 50% of the analysed samples from Algarve and Bragança, respectively, all samples were found to be compliant with European Commission. OTA content reached maximums of 0.49 ng/g in Algarve and 0.43 ng/g in Bragança, and was thus below the maximum limit established by European legislation for bread of 3 ng/g. The results of the present study put the estimated daily intake of OTA from bread at approximately 0.26 ng/kg bw/day in Algarve and 0.38 ng/kg bw/day in Bragança, circa 1.5% and 2.0% of the TDI established by either the EFSA or the FAO/WHO, or over 4.5% and 6.5% if we consider the FAO/WHO advised bread consumption of 250 g/day. These results seem to suggest that, in these two Portuguese regions, OTA contamination is well under control and unlikely to represent a threat to consumer health.application/pdfporDetermination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007Bento, J.M.V.Pena, A.Lino, C.M.PersonalPereira, J.A.DSpacehttp://dspace.org/items/7932162e-a2da-4913-b00d-17babbe51857DSpacehttp://dspace.org/items/7932162e-a2da-4913-b00d-17babbe51857PereiraJosé AlbertoCiência IDhttps://www.ciencia-id.pt611F-80B2-A7C1ORCIDhttp://orcid.org0000-0002-2260-0600Researcher IDhttps://www.researcherid.comL-6798-2014Scopus Author IDhttps://www.scopus.com57204366348HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf0026-265XDOIIsPartOf10.1016/j.microc.2008.10.0042011-01-10T15:41:52Z20092009-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/3042http://purl.org/coar/access_right/c_abf2open accessOchratoxin AWheat breadEDIAlgarveBragança258605 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/ff49e44a-b89b-4d44-bc59-eb67b9015b4f/downloadMicrochemical Journal91165169
spellingShingle Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
Bento, J.M.V.
Ochratoxin A
Wheat bread
EDI
Algarve
Bragança
status SINGLETON
subject.fl_str_mv Ochratoxin A
Wheat bread
EDI
Algarve
Bragança
title Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
title_full Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
title_fullStr Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
title_full_unstemmed Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
title_short Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
title_sort Determination of ochratoxin. A content in wheat bread samples collected from the Algarve and Bragança regions, Portugal: Winter 2007
topic Ochratoxin A
Wheat bread
EDI
Algarve
Bragança
topic_facet Ochratoxin A
Wheat bread
EDI
Algarve
Bragança
url http://hdl.handle.net/10198/3042
visible 1