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Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients

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Resumo:Moringa oleifera L. tree (Mo) has emerged as a rich alternative source of bioactive compounds to design cosmetic formulations. Supercritical carbon dioxide fluid extraction (SFE-CO2) was successfully applied on the screening of Mo seed, leaf, and root extracts. The extraction yield was evaluated by response surface methodology (RSM), for pressure and temperature ranges of 117–273 bar and 41–60 C, respectively, using a design of experiments (DOE). The pressure significantly affected the results (a = 0.05), with the highest extraction efficiency obtained at conditions above 195 bar. The extracts’ composition, evaluated by gas chromatography-mass spectrometer (GC-MS), revealed an increasing correlation between the pressure, total extract solubility, and mass of extract at a constant temperature, due to the higher extraction yield. Seed extracts presented more than 80% of oleic acid in relative composition (8.04 mgcompound gplantpart -1). Leaf extracts performed well for the obtainment of linolenic acid (>20%; 3.10 mg g-1), nonacosane (>22%; 0.46 mg g-1), and -tocopherol (>20%; 0.21 mg g-1). Mo root resulted in higher relative composition for sterol molecules, despite its very low affinity with CO2. The most promising bioactive compounds, oleic acid and -tocopherol, were more abundant when operating at 250 bar at 45 C and 195 bar at 55 C, for Mo seed and leaf SFE-CO2 extracts, respectively.
Autores principais:Kessler, Júlia C.
Outros Autores:Manrique, Yaidelin A.; Martins, Isabel M.; Rodrigues, Alírio; Barreiro, M.F.; Dias, Madalena M.
Assunto:Oleic acid α-tocopherol Cosmetic formulation
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Kessler, Júlia C.
author2 Manrique, Yaidelin A.
Martins, Isabel M.
Rodrigues, Alírio
Barreiro, M.F.
Dias, Madalena M.
author2_role author
author
author
author
author
author_facet Kessler, Júlia C.
Manrique, Yaidelin A.
Martins, Isabel M.
Rodrigues, Alírio
Barreiro, M.F.
Dias, Madalena M.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_str [{\"Person.name\":\"Kessler, Júlia C.\"},{\"Person.name\":\"Manrique, Yaidelin A.\"},{\"Person.name\":\"Martins, Isabel M.\"},{\"Person.name\":\"Rodrigues, Alírio\"},{\"Person.name\":\"Barreiro, M.F.\",\"Person.identifier.orcid\":\"0000-0002-6844-333X\"},{\"Person.name\":\"Dias, Madalena M.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Kessler, Júlia C.
Manrique, Yaidelin A.
Martins, Isabel M.
Rodrigues, Alírio
Barreiro, M.F.
Dias, Madalena M.
datacite.date.Accepted.fl_str_mv 2023-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2024-01-03T11:05:30Z
datacite.date.embargoed.fl_str_mv 2024-01-03T11:05:30Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Oleic acid
α-tocopherol
Cosmetic formulation
datacite.titles.title.fl_str_mv Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Kessler, Júlia C.
Manrique, Yaidelin A.
Martins, Isabel M.
Rodrigues, Alírio
Barreiro, M.F.
Dias, Madalena M.
dc.date.Accepted.fl_str_mv 2023-01-01T00:00:00Z
dc.date.available.fl_str_mv 2024-01-03T11:05:30Z
dc.date.embargoed.fl_str_mv 2024-01-03T11:05:30Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/29044
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv MDPI
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Oleic acid
α-tocopherol
Cosmetic formulation
dc.title.fl_str_mv Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Moringa oleifera L. tree (Mo) has emerged as a rich alternative source of bioactive compounds to design cosmetic formulations. Supercritical carbon dioxide fluid extraction (SFE-CO2) was successfully applied on the screening of Mo seed, leaf, and root extracts. The extraction yield was evaluated by response surface methodology (RSM), for pressure and temperature ranges of 117–273 bar and 41–60 C, respectively, using a design of experiments (DOE). The pressure significantly affected the results (a = 0.05), with the highest extraction efficiency obtained at conditions above 195 bar. The extracts’ composition, evaluated by gas chromatography-mass spectrometer (GC-MS), revealed an increasing correlation between the pressure, total extract solubility, and mass of extract at a constant temperature, due to the higher extraction yield. Seed extracts presented more than 80% of oleic acid in relative composition (8.04 mgcompound gplantpart -1). Leaf extracts performed well for the obtainment of linolenic acid (>20%; 3.10 mg g-1), nonacosane (>22%; 0.46 mg g-1), and -tocopherol (>20%; 0.21 mg g-1). Mo root resulted in higher relative composition for sterol molecules, despite its very low affinity with CO2. The most promising bioactive compounds, oleic acid and -tocopherol, were more abundant when operating at 250 bar at 45 C and 195 bar at 55 C, for Mo seed and leaf SFE-CO2 extracts, respectively.
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language eng
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network_name_str Biblioteca Digital do IPB
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/29044
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Kessler, Júlia C.
Manrique, Yaidelin A.
Martins, Isabel M.
Rodrigues, Alírio
Barreiro, M.F.
Barreiro, M.F.
https://www.ciencia-id.pt/3418-47D5-5746
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Dias, Madalena M.
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spelling engMDPIpt_PTMoringa oleifera L. tree (Mo) has emerged as a rich alternative source of bioactive compounds to design cosmetic formulations. Supercritical carbon dioxide fluid extraction (SFE-CO2) was successfully applied on the screening of Mo seed, leaf, and root extracts. The extraction yield was evaluated by response surface methodology (RSM), for pressure and temperature ranges of 117–273 bar and 41–60 C, respectively, using a design of experiments (DOE). The pressure significantly affected the results (a = 0.05), with the highest extraction efficiency obtained at conditions above 195 bar. The extracts’ composition, evaluated by gas chromatography-mass spectrometer (GC-MS), revealed an increasing correlation between the pressure, total extract solubility, and mass of extract at a constant temperature, due to the higher extraction yield. Seed extracts presented more than 80% of oleic acid in relative composition (8.04 mgcompound gplantpart -1). Leaf extracts performed well for the obtainment of linolenic acid (>20%; 3.10 mg g-1), nonacosane (>22%; 0.46 mg g-1), and -tocopherol (>20%; 0.21 mg g-1). Mo root resulted in higher relative composition for sterol molecules, despite its very low affinity with CO2. The most promising bioactive compounds, oleic acid and -tocopherol, were more abundant when operating at 250 bar at 45 C and 195 bar at 55 C, for Mo seed and leaf SFE-CO2 extracts, respectively.application/pdfpt_PTMoringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredientsKessler, Júlia C.Manrique, Yaidelin A.Martins, Isabel M.Rodrigues, AlírioPersonalBarreiro, M.F.DSpacehttp://dspace.org/items/0391987c-ba90-488b-839a-153447ce1f0fDSpacehttp://dspace.org/items/0391987c-ba90-488b-839a-153447ce1f0fBarreiroFilomenaCiência IDhttps://www.ciencia-id.pt3418-47D5-5746ORCIDhttp://orcid.org0000-0002-6844-333XResearcher IDhttps://www.researcherid.comL-9802-2014Scopus Author IDhttps://www.scopus.com57188719717Dias, Madalena M.HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptDOIIsPartOf10.3390/separations100302102024-01-03T11:05:30Z20232023-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/29044http://purl.org/coar/access_right/c_abf2open accessOleic acidα-tocopherolCosmetic formulation12289158 bytesFundação para a Ciência e a TecnologiaALICE - Associate Laboratory in Chemical Engineering6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaLaboratory of Separation and Reaction Engineering - Laboratory of Catalysis and Materials6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaSupercritical extraction and NETmix technology to produce green and stabilized M. oleifera functional ingredients having in view cosmeceutical formulationsPOR_NORTECrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal article2023http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/f915855e-27f9-492c-a328-28cb3450efbc/downloadSeparations103119
spellingShingle Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
Kessler, Júlia C.
Oleic acid
α-tocopherol
Cosmetic formulation
subject.fl_str_mv Oleic acid
α-tocopherol
Cosmetic formulation
title Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
title_full Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
title_fullStr Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
title_full_unstemmed Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
title_short Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
title_sort Moringa oleifera L. screening: SFE-CO2 optimisation and chemical composition of seed, leaf, and root extracts as potential cosmetic ingredients
topic Oleic acid
α-tocopherol
Cosmetic formulation
topic_facet Oleic acid
α-tocopherol
Cosmetic formulation
url http://hdl.handle.net/10198/29044
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