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Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application

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Resumo:Coleostephus myconis (L.) Rchb.f. is a rich source of phenolic acids which are possibly associated with its high antioxidant activity. In the present study, hydroethanolic extracts from two different botanical parts of C. myconis (senescent flowers; green parts) were incorporated into hydrosoluble gels. Bearing in mind the EC50 values from previous antioxidant activity evaluation assays, gels were prepared using a concentration of 0.25 mg/mL (senescent flowers) and 0.50 mg/mL (green parts). Since the inclusion of parabens is nowadays poorly accepted by the consumers, imidazolidinyl urea was included as the antimicrobial component. Gels had a non-greasy texture and good dermic absorption dynamics. Regarding pH evaluation, there were no significant alterations during the 180 days of observation (5.5 and 6.5). The antioxidant activity of the prepared hydrogels was assessed and compared with a blank formulation and also with the results obtained for the extracts alone. The antioxidant activity measured in each hydrosoluble gel was very similar to the value obtained for the isolated extract, in what regards TBARS and β-carotene bleaching inhibition, DPPH and reducing power, thereby indicating the suitability of the C. myconis extract to prepare this type of dermocosmetic products.
Autores principais:Bessada, Sílvia M.F.
Outros Autores:Barreira, João C.M.; Oliveira, Beatriz; Ferreira, Isabel C.F.R.
Ano:2016
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Bessada, Sílvia M.F.
author2 Barreira, João C.M.
Oliveira, Beatriz
Ferreira, Isabel C.F.R.
author2_role author
author
author
author_facet Bessada, Sílvia M.F.
Barreira, João C.M.
Oliveira, Beatriz
Ferreira, Isabel C.F.R.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_str [{\"Person.name\":\"Bessada, Sílvia M.F.\"},{\"Person.name\":\"Barreira, João C.M.\",\"Person.identifier.orcid\":\"0000-0003-1233-0990\"},{\"Person.name\":\"Oliveira, Beatriz\"},{\"Person.name\":\"Ferreira, Isabel C.F.R.\",\"Person.identifier.orcid\":\"0000-0003-4910-4882\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Bessada, Sílvia M.F.
Barreira, João C.M.
Oliveira, Beatriz
Ferreira, Isabel C.F.R.
datacite.date.Accepted.fl_str_mv 2016-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2018-03-05T15:38:53Z
datacite.date.embargoed.fl_str_mv 2018-03-05T15:38:53Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.titles.title.fl_str_mv Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Bessada, Sílvia M.F.
Barreira, João C.M.
Oliveira, Beatriz
Ferreira, Isabel C.F.R.
dc.date.Accepted.fl_str_mv 2016-01-01T00:00:00Z
dc.date.available.fl_str_mv 2018-03-05T15:38:53Z
dc.date.embargoed.fl_str_mv 2018-03-05T15:38:53Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/16188
dc.language.none.fl_str_mv eng
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.title.fl_str_mv Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_c94f
description Coleostephus myconis (L.) Rchb.f. is a rich source of phenolic acids which are possibly associated with its high antioxidant activity. In the present study, hydroethanolic extracts from two different botanical parts of C. myconis (senescent flowers; green parts) were incorporated into hydrosoluble gels. Bearing in mind the EC50 values from previous antioxidant activity evaluation assays, gels were prepared using a concentration of 0.25 mg/mL (senescent flowers) and 0.50 mg/mL (green parts). Since the inclusion of parabens is nowadays poorly accepted by the consumers, imidazolidinyl urea was included as the antimicrobial component. Gels had a non-greasy texture and good dermic absorption dynamics. Regarding pH evaluation, there were no significant alterations during the 180 days of observation (5.5 and 6.5). The antioxidant activity of the prepared hydrogels was assessed and compared with a blank formulation and also with the results obtained for the extracts alone. The antioxidant activity measured in each hydrosoluble gel was very similar to the value obtained for the isolated extract, in what regards TBARS and β-carotene bleaching inhibition, DPPH and reducing power, thereby indicating the suitability of the C. myconis extract to prepare this type of dermocosmetic products.
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person_str_mv Bessada, Sílvia M.F.
Barreira, João C.M.
Barreira, João C.M.
http://orcid.org/0000-0003-1233-0990
0000-0003-1233-0990
Oliveira, Beatriz
Ferreira, Isabel C.F.R.
Ferreira, Isabel C.F.R.
https://www.ciencia-id.pt/9418-CF95-9919
9418-CF95-9919
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spelling engpt_PTColeostephus myconis (L.) Rchb.f. is a rich source of phenolic acids which are possibly associated with its high antioxidant activity. In the present study, hydroethanolic extracts from two different botanical parts of C. myconis (senescent flowers; green parts) were incorporated into hydrosoluble gels. Bearing in mind the EC50 values from previous antioxidant activity evaluation assays, gels were prepared using a concentration of 0.25 mg/mL (senescent flowers) and 0.50 mg/mL (green parts). Since the inclusion of parabens is nowadays poorly accepted by the consumers, imidazolidinyl urea was included as the antimicrobial component. Gels had a non-greasy texture and good dermic absorption dynamics. Regarding pH evaluation, there were no significant alterations during the 180 days of observation (5.5 and 6.5). The antioxidant activity of the prepared hydrogels was assessed and compared with a blank formulation and also with the results obtained for the extracts alone. The antioxidant activity measured in each hydrosoluble gel was very similar to the value obtained for the isolated extract, in what regards TBARS and β-carotene bleaching inhibition, DPPH and reducing power, thereby indicating the suitability of the C. myconis extract to prepare this type of dermocosmetic products.application/pdfpt_PTDevelopment of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical applicationBessada, Sílvia M.F.PersonalBarreira, João C.M.DSpacehttp://dspace.org/items/4629b12c-39b0-4da8-8b8d-6efba5cf2d81DSpacehttp://dspace.org/items/4629b12c-39b0-4da8-8b8d-6efba5cf2d81BarreiraJoão C.M.ORCIDhttp://orcid.org0000-0003-1233-0990Researcher IDhttps://www.researcherid.comD-8269-2013Scopus Author IDhttps://www.scopus.com54895546900Oliveira, BeatrizPersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.pt2018-03-05T15:38:53Z20162016-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/16188http://purl.org/coar/access_right/c_abf2open access132355 bytesother research producthttp://purl.org/coar/resource_type/c_c94fconference object2016http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/062ab322-b717-49ce-8445-84c1c5f00075/downloadIJUP 2017Porto, Portugal
spellingShingle Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
Bessada, Sílvia M.F.
title Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
title_full Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
title_fullStr Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
title_full_unstemmed Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
title_short Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
title_sort Development of paraben-free hydrogel based on Coleostephus myconis (L.) Rchb.f. plant extracts for topical application
url http://hdl.handle.net/10198/16188
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