Publicação
Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis
| Resumo: | Salvia species are used worldwide for medicine purposes. In general, these medicinal plants have high amounts of flavonoids and phenolic acids, that are thought to be closely related to their health properties [1,2]. In this work, the aerial parts of Salvia farinacea, Salvia mexico, Salvia greggii and Salvia officinalis were extracted with hot water [3]. Extracts were evaluated for their total phenolic content by an adaptation of the Folin-Ciocalteu method and further analysed by high performance liquid chromatography associated with electrospray mass spectrometry (HPLC-DAD-ESI-MSn) in the negative ion mode [4], in order to identify their individual phenolic constituents. The aqueous extracts of S. farinacea, S. mexico, S. officinalis and S. greggii contained, respectively, 106±13, 159±38, 175±46 and 136±1 μg GAE/mg of total phenolics. These four species were characterized by a clear prevalence of caffeic acid derivatives, in particular of rosmarinic acid (MW 360), that is generally the most abundant phenolic compound in Salvia species [2,3]. In addition, S. mexico and S. officinalis contained moderate amounts of salvianolic acid B (MW 718). Among these two, S. mexico was richer in O-caffeoylquinic acid (MW 354), while the latter presented high amounts of salvianolic acid K (MW 556) and moderate amounts of its structural isomer. All the extracts were enriched in flavones: S. farinacea and S. officinalis contained high amounts of luteolin-O-glucuronide while S. mexico contained luteolin-C-glucoside with respective characteristic mass spectrometry fragmentation pattern m/z at 461→285 and m/z at 447→357, 327. Similarly, S. greggii extract presented high content of luteolin-7-O-glucoside ([M-H]− at m/z 447→ 285) and luteolin-C-glucoside and moderate quantities of apigenin-C-hexoside ([M-H]− at m/z 431→341, 311). Further studies are being undertaken in order to understand the contribution of these phenolic constituents in the biological activities of Salvia plants. |
|---|---|
| Autores principais: | Pereira, Olívia R. |
| Outros Autores: | Afonso, Andrea Luísa Fernandes; Cardoso, Susana M. |
| Assunto: | Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| Ano: | 2016 |
| País: | Portugal |
| Tipo de documento: | póster em conferência |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1867173342736285696 |
|---|---|
| author | Pereira, Olívia R. |
| author2 | Afonso, Andrea Luísa Fernandes Cardoso, Susana M. |
| author2_role | author author |
| author_facet | Pereira, Olívia R. Afonso, Andrea Luísa Fernandes Cardoso, Susana M. |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Pereira, Olívia R.\",\"Person.identifier.orcid\":\"0000-0002-6275-3134\"},{\"Person.name\":\"Afonso, Andrea Luísa Fernandes\",\"Person.identifier.orcid\":\"0000-0002-8858-1617\"},{\"Person.name\":\"Cardoso, Susana M.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Pereira, Olívia R. Afonso, Andrea Luísa Fernandes Cardoso, Susana M. |
| datacite.date.Accepted.fl_str_mv | 2016-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2016-09-12T15:11:28Z |
| datacite.date.embargoed.fl_str_mv | 2016-09-12T15:11:28Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| datacite.subjects.subject.fl_str_mv | Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| datacite.titles.title.fl_str_mv | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Pereira, Olívia R. Afonso, Andrea Luísa Fernandes Cardoso, Susana M. |
| dc.date.Accepted.fl_str_mv | 2016-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2016-09-12T15:11:28Z |
| dc.date.embargoed.fl_str_mv | 2016-09-12T15:11:28Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/13226 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Universidade de Coimbra, Faculdade de Farmácia Universidade de Coimbra |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| dc.subject.none.fl_str_mv | Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| dc.title.fl_str_mv | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6670 |
| description | Salvia species are used worldwide for medicine purposes. In general, these medicinal plants have high amounts of flavonoids and phenolic acids, that are thought to be closely related to their health properties [1,2]. In this work, the aerial parts of Salvia farinacea, Salvia mexico, Salvia greggii and Salvia officinalis were extracted with hot water [3]. Extracts were evaluated for their total phenolic content by an adaptation of the Folin-Ciocalteu method and further analysed by high performance liquid chromatography associated with electrospray mass spectrometry (HPLC-DAD-ESI-MSn) in the negative ion mode [4], in order to identify their individual phenolic constituents. The aqueous extracts of S. farinacea, S. mexico, S. officinalis and S. greggii contained, respectively, 106±13, 159±38, 175±46 and 136±1 μg GAE/mg of total phenolics. These four species were characterized by a clear prevalence of caffeic acid derivatives, in particular of rosmarinic acid (MW 360), that is generally the most abundant phenolic compound in Salvia species [2,3]. In addition, S. mexico and S. officinalis contained moderate amounts of salvianolic acid B (MW 718). Among these two, S. mexico was richer in O-caffeoylquinic acid (MW 354), while the latter presented high amounts of salvianolic acid K (MW 556) and moderate amounts of its structural isomer. All the extracts were enriched in flavones: S. farinacea and S. officinalis contained high amounts of luteolin-O-glucuronide while S. mexico contained luteolin-C-glucoside with respective characteristic mass spectrometry fragmentation pattern m/z at 461→285 and m/z at 447→357, 327. Similarly, S. greggii extract presented high content of luteolin-7-O-glucoside ([M-H]− at m/z 447→ 285) and luteolin-C-glucoside and moderate quantities of apigenin-C-hexoside ([M-H]− at m/z 431→341, 311). Further studies are being undertaken in order to understand the contribution of these phenolic constituents in the biological activities of Salvia plants. |
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| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
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| person_str_mv | Pereira, Olívia R. Pereira, Olívia R. https://www.ciencia-id.pt/B312-AF21-D2FA B312-AF21-D2FA http://orcid.org/0000-0002-6275-3134 0000-0002-6275-3134 Afonso, Andrea Luísa Fernandes Afonso, Andrea Luísa Fernandes https://www.ciencia-id.pt/9C1D-41E7-9BBF 9C1D-41E7-9BBF http://orcid.org/0000-0002-8858-1617 0000-0002-8858-1617 Cardoso, Susana M. |
| publishDate | 2016 |
| publisher.none.fl_str_mv | Universidade de Coimbra, Faculdade de Farmácia Universidade de Coimbra |
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| spelling | engUniversidade de Coimbra, Faculdade de Farmácia Universidade de Coimbrapt_PTSalvia species are used worldwide for medicine purposes. In general, these medicinal plants have high amounts of flavonoids and phenolic acids, that are thought to be closely related to their health properties [1,2]. In this work, the aerial parts of Salvia farinacea, Salvia mexico, Salvia greggii and Salvia officinalis were extracted with hot water [3]. Extracts were evaluated for their total phenolic content by an adaptation of the Folin-Ciocalteu method and further analysed by high performance liquid chromatography associated with electrospray mass spectrometry (HPLC-DAD-ESI-MSn) in the negative ion mode [4], in order to identify their individual phenolic constituents. The aqueous extracts of S. farinacea, S. mexico, S. officinalis and S. greggii contained, respectively, 106±13, 159±38, 175±46 and 136±1 μg GAE/mg of total phenolics. These four species were characterized by a clear prevalence of caffeic acid derivatives, in particular of rosmarinic acid (MW 360), that is generally the most abundant phenolic compound in Salvia species [2,3]. In addition, S. mexico and S. officinalis contained moderate amounts of salvianolic acid B (MW 718). Among these two, S. mexico was richer in O-caffeoylquinic acid (MW 354), while the latter presented high amounts of salvianolic acid K (MW 556) and moderate amounts of its structural isomer. All the extracts were enriched in flavones: S. farinacea and S. officinalis contained high amounts of luteolin-O-glucuronide while S. mexico contained luteolin-C-glucoside with respective characteristic mass spectrometry fragmentation pattern m/z at 461→285 and m/z at 447→357, 327. Similarly, S. greggii extract presented high content of luteolin-7-O-glucoside ([M-H]− at m/z 447→ 285) and luteolin-C-glucoside and moderate quantities of apigenin-C-hexoside ([M-H]− at m/z 431→341, 311). Further studies are being undertaken in order to understand the contribution of these phenolic constituents in the biological activities of Salvia plants.application/pdfpt_PTPhenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalisPersonalPereira, Olívia R.DSpacehttp://dspace.org/items/e8fdab9a-3ad6-47e6-b90c-7a37aabcb453DSpacehttp://dspace.org/items/e8fdab9a-3ad6-47e6-b90c-7a37aabcb453PereiraOlívia R.Ciência IDhttps://www.ciencia-id.ptB312-AF21-D2FAORCIDhttp://orcid.org0000-0002-6275-3134Researcher IDhttps://www.researcherid.comH-1049-2014Scopus Author IDhttps://www.scopus.com52264387000PersonalAfonso, Andrea Luísa FernandesDSpacehttp://dspace.org/items/af7d647c-f5a6-48f7-afcf-6307c3677b1dDSpacehttp://dspace.org/items/af7d647c-f5a6-48f7-afcf-6307c3677b1dAfonsoAndrea Luísa FernandesCiência IDhttps://www.ciencia-id.pt9C1D-41E7-9BBFORCIDhttp://orcid.org0000-0002-8858-1617Scopus Author IDhttps://www.scopus.com36766901000Cardoso, Susana M.HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.pt2016-09-12T15:11:28Z20162016-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/13226http://purl.org/coar/access_right/c_16ecrestricted accessSalviaLamiaceaePhenolic characterizationCaffeic acid derivatives739437 bytesother research producthttp://purl.org/coar/resource_type/c_6670conference poster2016http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/045217a4-9cb8-4ad0-a92d-ee9db70227de/download6 th International Congress of Aromatic and Medicinal PlantsCoimbra |
| spellingShingle | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis Pereira, Olívia R. Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| status | SINGLETON |
| subject.fl_str_mv | Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| title | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| title_full | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| title_fullStr | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| title_full_unstemmed | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| title_short | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| title_sort | Phenolic composition of four sage species: salvia farinacea, salvia mexico, salvia greggii and salvia officinalis |
| topic | Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| topic_facet | Salvia Lamiaceae Phenolic characterization Caffeic acid derivatives |
| url | http://hdl.handle.net/10198/13226 |
| visible | 1 |