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Alkaloids from fungi

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Resumo:The prospection of unusual sources and undiscovered habitats is valuable in natural product research. Indeed, the fungi kingdom has received special attention since its ability to produce novel and intriguing secondary metabolites with various biological uses. Among secondary metabolites, alkaloid-derived structures present a wide range of bioactivities, including antineurodegenerative, antidepressive, anxiolytic, anti-inflammatory, cytotoxic, and insecticidal properties. Furthermore, various studies showed particular properties of those alkaloids in reducing nicotine addiction and alcohol dependence. Alkaloids are categorized into several groups based on their heterocyclic ring system and biosynthetic precursor, such as indole, isoxazoles, and muscarine. Therefore, this chapter focuses on those fungi’s bioactive alkaloids with emphasis on pharmacokinetics as well as the current analytical approaches for extraction and compound identification. Furthermore, the main biological activities and action mechanisms of these fungus alkaloids will also be discussed.
Autores principais:Silva, Jani
Outros Autores:Garcia, Juliana; Guimarães, Rafaela; Palito, Cátia; Lemos, André; Barros, Lillian; Alves, Maria José
Assunto:Alkaloids Hallucinogenic mushrooms Indoles; Isoxazoles Muscarine
Ano:2023
País:Portugal
Tipo de documento:capítulo de livro
Tipo de acesso:acesso restrito
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB

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