Publicação
Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods
| Resumo: | Nutraceuticals and functional foods are composed of especially complex matrices, with polyphenols, carotenoids, minerals, and vitamins, among others, being the main classes of phytochemicals involved in their bioactivities. Despite their wide use, further investigations are needed to certify the proper release of these phytochemicals into the gastrointestinal medium, where the bioaccessibility assay is one of the most frequently used method. The aim of this review was to gather and describe different methods that can be used to assess the bioaccessibility of nutraceuticals and functional foods, along with the most important factors that can impact this process. The link between simulated digestion testing of phytochemicals and their in vitro bioactivity is also discussed, with a special focus on the potential of developing nutraceuticals and functional foods from simple plant materials. The bioactive potential of certain classes of phytochemicals from nutraceuticals and functional foods is susceptible to different variations during the bioaccessibility assessment, with different factors contributing to this variability, namely the chemical composition and the nature of the matrix. Regardless of the high number of studies, the current methodology fails to assume correlations between bioaccessibility and bioactivity, and the findings of this review indicate a necessity for updated and standardized protocols. |
|---|---|
| Autores principais: | Nicolescu, Alexandru |
| Outros Autores: | Babotă, Mihai; Barros, Lillian; Lucini, Luigi; Tanase, Corneliu; Mocan, Andrei; Bunea, Claudiu I.; Crisan, Gianina |
| Assunto: | Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1863851406751956992 |
|---|---|
| author | Nicolescu, Alexandru |
| author2 | Babotă, Mihai Barros, Lillian Lucini, Luigi Tanase, Corneliu Mocan, Andrei Bunea, Claudiu I. Crisan, Gianina |
| author2_role | author author author author author author author |
| author_facet | Nicolescu, Alexandru Babotă, Mihai Barros, Lillian Lucini, Luigi Tanase, Corneliu Mocan, Andrei Bunea, Claudiu I. Crisan, Gianina |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Nicolescu, Alexandru\"},{\"Person.name\":\"Babotă, Mihai\"},{\"Person.name\":\"Barros, Lillian\",\"Person.identifier.orcid\":\"0000-0002-9050-5189\"},{\"Person.name\":\"Lucini, Luigi\"},{\"Person.name\":\"Tanase, Corneliu\"},{\"Person.name\":\"Mocan, Andrei\"},{\"Person.name\":\"Bunea, Claudiu I.\"},{\"Person.name\":\"Crisan, Gianina\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Nicolescu, Alexandru Babotă, Mihai Barros, Lillian Lucini, Luigi Tanase, Corneliu Mocan, Andrei Bunea, Claudiu I. Crisan, Gianina |
| datacite.date.Accepted.fl_str_mv | 2023-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2014-11-19T09:03:24Z |
| datacite.date.embargoed.fl_str_mv | 2014-11-19T09:03:24Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| datacite.titles.title.fl_str_mv | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Nicolescu, Alexandru Babotă, Mihai Barros, Lillian Lucini, Luigi Tanase, Corneliu Mocan, Andrei Bunea, Claudiu I. Crisan, Gianina |
| dc.date.Accepted.fl_str_mv | 2023-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2014-11-19T09:03:24Z |
| dc.date.embargoed.fl_str_mv | 2014-11-19T09:03:24Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/11398 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Frontiers |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| dc.title.fl_str_mv | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Nutraceuticals and functional foods are composed of especially complex matrices, with polyphenols, carotenoids, minerals, and vitamins, among others, being the main classes of phytochemicals involved in their bioactivities. Despite their wide use, further investigations are needed to certify the proper release of these phytochemicals into the gastrointestinal medium, where the bioaccessibility assay is one of the most frequently used method. The aim of this review was to gather and describe different methods that can be used to assess the bioaccessibility of nutraceuticals and functional foods, along with the most important factors that can impact this process. The link between simulated digestion testing of phytochemicals and their in vitro bioactivity is also discussed, with a special focus on the potential of developing nutraceuticals and functional foods from simple plant materials. The bioactive potential of certain classes of phytochemicals from nutraceuticals and functional foods is susceptible to different variations during the bioaccessibility assessment, with different factors contributing to this variability, namely the chemical composition and the nature of the matrix. Regardless of the high number of studies, the current methodology fails to assume correlations between bioaccessibility and bioactivity, and the findings of this review indicate a necessity for updated and standardized protocols. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://bibliotecadigital.ipb.pt/bitstreams/ef582fba-bc9e-4032-bbc3-5482ce36a798/download |
| id | ipb_cca7a67f6f6c263aca470f4d805dfc8e |
| identifier.url.fl_str_mv | http://hdl.handle.net/10198/11398 |
| instacron_str | ipb |
| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
| network_acronym_str | ipb |
| network_name_str | Biblioteca Digital do IPB |
| oai_identifier_str | oai:bibliotecadigital.ipb.pt:10198/11398 |
| organization_str_mv | urn:organizationAcronym:ipb |
| person_str_mv | Nicolescu, Alexandru Babotă, Mihai Barros, Lillian Barros, Lillian https://www.ciencia-id.pt/9616-35CB-D001 9616-35CB-D001 http://orcid.org/0000-0002-9050-5189 0000-0002-9050-5189 Lucini, Luigi Tanase, Corneliu Mocan, Andrei Bunea, Claudiu I. Crisan, Gianina |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Frontiers |
| reponame_str | Biblioteca Digital do IPB |
| repository_id_str | urn:repositoryAcronym:ipb |
| service_str_mv | urn:repositoryAcronym:ipb |
| spelling | engFrontiersporNutraceuticals and functional foods are composed of especially complex matrices, with polyphenols, carotenoids, minerals, and vitamins, among others, being the main classes of phytochemicals involved in their bioactivities. Despite their wide use, further investigations are needed to certify the proper release of these phytochemicals into the gastrointestinal medium, where the bioaccessibility assay is one of the most frequently used method. The aim of this review was to gather and describe different methods that can be used to assess the bioaccessibility of nutraceuticals and functional foods, along with the most important factors that can impact this process. The link between simulated digestion testing of phytochemicals and their in vitro bioactivity is also discussed, with a special focus on the potential of developing nutraceuticals and functional foods from simple plant materials. The bioactive potential of certain classes of phytochemicals from nutraceuticals and functional foods is susceptible to different variations during the bioaccessibility assessment, with different factors contributing to this variability, namely the chemical composition and the nature of the matrix. Regardless of the high number of studies, the current methodology fails to assume correlations between bioaccessibility and bioactivity, and the findings of this review indicate a necessity for updated and standardized protocols.application/pdfporBioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foodsNicolescu, AlexandruBabotă, MihaiPersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801Lucini, LuigiTanase, CorneliuMocan, AndreiBunea, Claudiu I.Crisan, GianinaHostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf2296-861XDOIIsPartOf10.3389/fnut.2023.11845352014-11-19T09:03:24Z20232023-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/11398http://purl.org/coar/access_right/c_abf2open accessBioaccessibilityNutraceuticalsFunctional foodsPhytonutrientsPolyphenolsCarotenoids1411613 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/ef582fba-bc9e-4032-bbc3-5482ce36a798/downloadFrontiers in Nutrition |
| spellingShingle | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods Nicolescu, Alexandru Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| subject.fl_str_mv | Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| title | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| title_full | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| title_fullStr | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| title_full_unstemmed | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| title_short | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| title_sort | Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods |
| topic | Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| topic_facet | Bioaccessibility Nutraceuticals Functional foods Phytonutrients Polyphenols Carotenoids |
| url | http://hdl.handle.net/10198/11398 |
| visible | 1 |