Publicação
Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study
| Resumo: | The production of chestnut (Castanea sativa Miller) is mostly concentrated in Europe. Chestnut is recognized by its high content of antioxidants and phytosterols. This work aimed to evaluate the e ects of dietary chestnut consumption over physiological variables of FVB/n mice. Eighteen FVB/n male 7-month-old mice were randomly divided into three experimental groups (n = 6): 1 (control group) fed a standard diet; 2 fed a diet supplemented with 0.55% (w/w) chestnut; and 3 supplemented with 1.1% (w/w) chestnut. Body weight, water, and food intake were recorded weekly. Following 35 days of supplementation, the mice were sacrificed for the collection of biological samples. Chestnut supplementation at 1.1% reduced abdominal adipose tissue. Lower serum cholesterol was also observed in animals supplemented with chestnut. There were no significant di erences concerning the incidence of histological lesions nor in biochemical markers of hepatic damage and oxidative stress. These results suggest that chestnut supplementation may contribute to regulate adipose tissue deposition. |
|---|---|
| Autores principais: | Rodrigues, Pedro M. |
| Outros Autores: | Ferreira, Tiago; Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Costa, Rui Miguel Gil; Martins, Tânia; Neuparth, Maria João; Pires, Maria João; Lanzarin, Germano; Félix, Luís; Venâncio, Carlos; Ferreira, Isabel C.F.R.; Bastos, Margarida M.S.M.; Medeiros, Rui; Gaivão, Isabel; Rosa, Eduardo; Oliveira, Paula A. |
| Assunto: | Adipose tissue Cholesterol In vivo Oxidative stress |
| Ano: | 2020 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1863851046982385664 |
|---|---|
| author | Rodrigues, Pedro M. |
| author2 | Ferreira, Tiago Nascimento-Gonçalves, Elisabete Seixas, Fernanda Costa, Rui Miguel Gil Martins, Tânia Neuparth, Maria João Pires, Maria João Lanzarin, Germano Félix, Luís Venâncio, Carlos Ferreira, Isabel C.F.R. Bastos, Margarida M.S.M. Medeiros, Rui Gaivão, Isabel Rosa, Eduardo Oliveira, Paula A. |
| author2_role | author author author author author author author author author author author author author author author author |
| author_facet | Rodrigues, Pedro M. Ferreira, Tiago Nascimento-Gonçalves, Elisabete Seixas, Fernanda Costa, Rui Miguel Gil Martins, Tânia Neuparth, Maria João Pires, Maria João Lanzarin, Germano Félix, Luís Venâncio, Carlos Ferreira, Isabel C.F.R. Bastos, Margarida M.S.M. Medeiros, Rui Gaivão, Isabel Rosa, Eduardo Oliveira, Paula A. |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Rodrigues, Pedro M.\",\"Person.identifier.orcid\":\"0009-0002-4920-7398\"},{\"Person.name\":\"Ferreira, Tiago\"},{\"Person.name\":\"Nascimento-Gonçalves, Elisabete\"},{\"Person.name\":\"Seixas, Fernanda\"},{\"Person.name\":\"Costa, Rui Miguel Gil\"},{\"Person.name\":\"Martins, Tânia\"},{\"Person.name\":\"Neuparth, Maria João\"},{\"Person.name\":\"Pires, Maria João\"},{\"Person.name\":\"Lanzarin, Germano\"},{\"Person.name\":\"Félix, Luís\"},{\"Person.name\":\"Venâncio, Carlos\"},{\"Person.name\":\"Ferreira, Isabel C.F.R.\",\"Person.identifier.orcid\":\"0000-0003-4910-4882\"},{\"Person.name\":\"Bastos, Margarida M.S.M.\"},{\"Person.name\":\"Medeiros, Rui\"},{\"Person.name\":\"Gaivão, Isabel\"},{\"Person.name\":\"Rosa, Eduardo\"},{\"Person.name\":\"Oliveira, Paula A.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Rodrigues, Pedro M. Ferreira, Tiago Nascimento-Gonçalves, Elisabete Seixas, Fernanda Costa, Rui Miguel Gil Martins, Tânia Neuparth, Maria João Pires, Maria João Lanzarin, Germano Félix, Luís Venâncio, Carlos Ferreira, Isabel C.F.R. Bastos, Margarida M.S.M. Medeiros, Rui Gaivão, Isabel Rosa, Eduardo Oliveira, Paula A. |
| datacite.date.Accepted.fl_str_mv | 2020-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2018-01-19T10:00:00Z |
| datacite.date.embargoed.fl_str_mv | 2018-01-19T10:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Adipose tissue Cholesterol In vivo Oxidative stress |
| datacite.titles.title.fl_str_mv | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Rodrigues, Pedro M. Ferreira, Tiago Nascimento-Gonçalves, Elisabete Seixas, Fernanda Costa, Rui Miguel Gil Martins, Tânia Neuparth, Maria João Pires, Maria João Lanzarin, Germano Félix, Luís Venâncio, Carlos Ferreira, Isabel C.F.R. Bastos, Margarida M.S.M. Medeiros, Rui Gaivão, Isabel Rosa, Eduardo Oliveira, Paula A. |
| dc.date.Accepted.fl_str_mv | 2020-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2018-01-19T10:00:00Z |
| dc.date.embargoed.fl_str_mv | 2018-01-19T10:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/22316 |
| dc.language.none.fl_str_mv | eng |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Adipose tissue Cholesterol In vivo Oxidative stress |
| dc.title.fl_str_mv | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The production of chestnut (Castanea sativa Miller) is mostly concentrated in Europe. Chestnut is recognized by its high content of antioxidants and phytosterols. This work aimed to evaluate the e ects of dietary chestnut consumption over physiological variables of FVB/n mice. Eighteen FVB/n male 7-month-old mice were randomly divided into three experimental groups (n = 6): 1 (control group) fed a standard diet; 2 fed a diet supplemented with 0.55% (w/w) chestnut; and 3 supplemented with 1.1% (w/w) chestnut. Body weight, water, and food intake were recorded weekly. Following 35 days of supplementation, the mice were sacrificed for the collection of biological samples. Chestnut supplementation at 1.1% reduced abdominal adipose tissue. Lower serum cholesterol was also observed in animals supplemented with chestnut. There were no significant di erences concerning the incidence of histological lesions nor in biochemical markers of hepatic damage and oxidative stress. These results suggest that chestnut supplementation may contribute to regulate adipose tissue deposition. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://bibliotecadigital.ipb.pt/bitstreams/e96ef2cc-24f0-49cc-8bf6-5081be592946/download |
| id | ipb_cda4c0a9bba2f08302ee4e86e07d22ef |
| identifier.url.fl_str_mv | http://hdl.handle.net/10198/22316 |
| instacron_str | ipb |
| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
| network_acronym_str | ipb |
| network_name_str | Biblioteca Digital do IPB |
| oai_identifier_str | oai:bibliotecadigital.ipb.pt:10198/22316 |
| organization_str_mv | urn:organizationAcronym:ipb |
| person_str_mv | Rodrigues, Pedro M. Rodrigues, Pedro M. https://www.ciencia-id.pt/C919-D413-5E83 C919-D413-5E83 http://orcid.org/0009-0002-4920-7398 0009-0002-4920-7398 Ferreira, Tiago Nascimento-Gonçalves, Elisabete Seixas, Fernanda Costa, Rui Miguel Gil Martins, Tânia Neuparth, Maria João Pires, Maria João Lanzarin, Germano Félix, Luís Venâncio, Carlos Ferreira, Isabel C.F.R. Ferreira, Isabel C.F.R. https://www.ciencia-id.pt/9418-CF95-9919 9418-CF95-9919 http://orcid.org/0000-0003-4910-4882 0000-0003-4910-4882 Bastos, Margarida M.S.M. Medeiros, Rui Gaivão, Isabel Rosa, Eduardo Oliveira, Paula A. |
| publishDate | 2020 |
| reponame_str | Biblioteca Digital do IPB |
| repository_id_str | urn:repositoryAcronym:ipb |
| service_str_mv | urn:repositoryAcronym:ipb |
| spelling | engThe production of chestnut (Castanea sativa Miller) is mostly concentrated in Europe. Chestnut is recognized by its high content of antioxidants and phytosterols. This work aimed to evaluate the e ects of dietary chestnut consumption over physiological variables of FVB/n mice. Eighteen FVB/n male 7-month-old mice were randomly divided into three experimental groups (n = 6): 1 (control group) fed a standard diet; 2 fed a diet supplemented with 0.55% (w/w) chestnut; and 3 supplemented with 1.1% (w/w) chestnut. Body weight, water, and food intake were recorded weekly. Following 35 days of supplementation, the mice were sacrificed for the collection of biological samples. Chestnut supplementation at 1.1% reduced abdominal adipose tissue. Lower serum cholesterol was also observed in animals supplemented with chestnut. There were no significant di erences concerning the incidence of histological lesions nor in biochemical markers of hepatic damage and oxidative stress. These results suggest that chestnut supplementation may contribute to regulate adipose tissue deposition.application/pdfen_ENDietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary studyPersonalRodrigues, Pedro M.DSpacehttp://dspace.org/items/55f77b39-347e-4ad5-97c6-def43d656014DSpacehttp://dspace.org/items/55f77b39-347e-4ad5-97c6-def43d656014RodriguesPedro M.Ciência IDhttps://www.ciencia-id.ptC919-D413-5E83ORCIDhttp://orcid.org0009-0002-4920-7398Scopus Author IDhttps://www.scopus.com56108282100Ferreira, TiagoNascimento-Gonçalves, ElisabeteSeixas, FernandaCosta, Rui Miguel GilMartins, TâniaNeuparth, Maria JoãoPires, Maria JoãoLanzarin, GermanoFélix, LuísVenâncio, CarlosPersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600Bastos, Margarida M.S.M.Medeiros, RuiGaivão, IsabelRosa, EduardoOliveira, Paula A.HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptDOIIsPartOf10.3390/biomedicines80400752018-01-19T10:00:00Z20202020-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/22316http://purl.org/coar/access_right/c_abf2open accessAdipose tissueCholesterolIn vivoOxidative stress294500 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/e96ef2cc-24f0-49cc-8bf6-5081be592946/download |
| spellingShingle | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study Rodrigues, Pedro M. Adipose tissue Cholesterol In vivo Oxidative stress |
| subject.fl_str_mv | Adipose tissue Cholesterol In vivo Oxidative stress |
| title | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| title_full | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| title_fullStr | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| title_full_unstemmed | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| title_short | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| title_sort | Dietary supplementation with chestnut (Castanea sativa) reduces abdominal adiposity in FVB/n mice: a preliminary study |
| topic | Adipose tissue Cholesterol In vivo Oxidative stress |
| topic_facet | Adipose tissue Cholesterol In vivo Oxidative stress |
| url | http://hdl.handle.net/10198/22316 |
| visible | 1 |