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Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity

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Resumo:Betalains are a group of secondary metabolites named chromoalkaloids that are synthesized from tyrosine. These compounds have gained some attention in the last few years mainly due to their interesting bioactive potential, namely antioxidant, antimicrobial, and other bioactive properties [1]. Their strong and vibrant colours are also one of the characteristics by which these compounds have gained visibility in the food and pharmaceutical industries [2]. Betalains can be divided in two groups regarding the colour range: betaxanthins in the orange to yellow range, and betacyanins in the purple to pink range. Thereby, these compounds can be used as natural colouring agents, providing alternatives to the massively used artificial counterparts [3]. Although there are already some natural options in the market, these are not enough to meet the needs of the food industry, due to the growing concern of consumers regarding what they eat. Thus, the objectives of this work were to: i) obtain bioactive extracts and with strong colouring capacity from the epicarp of two pitaya varieties, white-fleshed pitaya Hylocereus undatus (Haworth) Britton & Rose (WFP) and red-fleshed pitaya Hylocereus costaricensis (F.A.C.Weber) Britton & Rose (RFP); ii) chemically characterize the betalains’ content through HPLC-DAD-ESI/MS; iii) evaluate the bioactive properties of the extracts, namely antimicrobial activity. The extracts were obtained through a dynamic maceration assisted by heat, and the betacyanins’ profile was characterized by HPLC-DAD-ESI/MS. The antibacterial capacity was determined against a panel of Gram-negative and Gram-positive bacteria using the colorimetric method of rapid detection with p-iodonitrotetrazolium chloride (INT), and the responses obtained were expressed as minimum inhibitory (MIC) and minimum bactericidal (MBC) concentrations. By the chromatographic analysis of the extracts it was possible to identify six compounds in both samples. For the WFP the major compounds identified were 6'-O-malonylbetanin (phylocactin), followed by 4'-malonyl-betanin, while for the RFP the major compound found was phylocactin. In the evaluation of the antibacterial activity, both extracts showed MIC and MBC values that ranged from 10 to 20 mg/mL. Gram-positive bacteria showed to be more susceptible to both extracts then the negative strains. Further studies need to be conducted to better understand the correlation between the bioactive potential and the betacyanins’ composition. Nevertheless, these natural matrixes proved to be viable alternatives for obtaining colouring extracts with antimicrobial properties.
Autores principais:Roriz, Custódio Lobo
Outros Autores:Dias, Maria Inês; Reis, Filipa S.; Pires, Tânia C.S.; Alves, Maria José; Fernandes, Filipa A.; Morales, Patricia; Barros, Lillian; Ferreira, Isabel C.F.R.
Assunto:Dragon fruits
Ano:2019
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Roriz, Custódio Lobo
author2 Dias, Maria Inês
Reis, Filipa S.
Pires, Tânia C.S.
Alves, Maria José
Fernandes, Filipa A.
Morales, Patricia
Barros, Lillian
Ferreira, Isabel C.F.R.
author2_role author
author
author
author
author
author
author
author
author_facet Roriz, Custódio Lobo
Dias, Maria Inês
Reis, Filipa S.
Pires, Tânia C.S.
Alves, Maria José
Fernandes, Filipa A.
Morales, Patricia
Barros, Lillian
Ferreira, Isabel C.F.R.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
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datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Roriz, Custódio Lobo
Dias, Maria Inês
Reis, Filipa S.
Pires, Tânia C.S.
Alves, Maria José
Fernandes, Filipa A.
Morales, Patricia
Barros, Lillian
Ferreira, Isabel C.F.R.
datacite.date.Accepted.fl_str_mv 2019-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2019-06-19T15:05:21Z
datacite.date.embargoed.fl_str_mv 2019-06-19T15:05:21Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Dragon fruits
datacite.titles.title.fl_str_mv Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Roriz, Custódio Lobo
Dias, Maria Inês
Reis, Filipa S.
Pires, Tânia C.S.
Alves, Maria José
Fernandes, Filipa A.
Morales, Patricia
Barros, Lillian
Ferreira, Isabel C.F.R.
dc.date.Accepted.fl_str_mv 2019-01-01T00:00:00Z
dc.date.available.fl_str_mv 2019-06-19T15:05:21Z
dc.date.embargoed.fl_str_mv 2019-06-19T15:05:21Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/19353
dc.language.none.fl_str_mv eng
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Dragon fruits
dc.title.fl_str_mv Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_c94f
description Betalains are a group of secondary metabolites named chromoalkaloids that are synthesized from tyrosine. These compounds have gained some attention in the last few years mainly due to their interesting bioactive potential, namely antioxidant, antimicrobial, and other bioactive properties [1]. Their strong and vibrant colours are also one of the characteristics by which these compounds have gained visibility in the food and pharmaceutical industries [2]. Betalains can be divided in two groups regarding the colour range: betaxanthins in the orange to yellow range, and betacyanins in the purple to pink range. Thereby, these compounds can be used as natural colouring agents, providing alternatives to the massively used artificial counterparts [3]. Although there are already some natural options in the market, these are not enough to meet the needs of the food industry, due to the growing concern of consumers regarding what they eat. Thus, the objectives of this work were to: i) obtain bioactive extracts and with strong colouring capacity from the epicarp of two pitaya varieties, white-fleshed pitaya Hylocereus undatus (Haworth) Britton & Rose (WFP) and red-fleshed pitaya Hylocereus costaricensis (F.A.C.Weber) Britton & Rose (RFP); ii) chemically characterize the betalains’ content through HPLC-DAD-ESI/MS; iii) evaluate the bioactive properties of the extracts, namely antimicrobial activity. The extracts were obtained through a dynamic maceration assisted by heat, and the betacyanins’ profile was characterized by HPLC-DAD-ESI/MS. The antibacterial capacity was determined against a panel of Gram-negative and Gram-positive bacteria using the colorimetric method of rapid detection with p-iodonitrotetrazolium chloride (INT), and the responses obtained were expressed as minimum inhibitory (MIC) and minimum bactericidal (MBC) concentrations. By the chromatographic analysis of the extracts it was possible to identify six compounds in both samples. For the WFP the major compounds identified were 6'-O-malonylbetanin (phylocactin), followed by 4'-malonyl-betanin, while for the RFP the major compound found was phylocactin. In the evaluation of the antibacterial activity, both extracts showed MIC and MBC values that ranged from 10 to 20 mg/mL. Gram-positive bacteria showed to be more susceptible to both extracts then the negative strains. Further studies need to be conducted to better understand the correlation between the bioactive potential and the betacyanins’ composition. Nevertheless, these natural matrixes proved to be viable alternatives for obtaining colouring extracts with antimicrobial properties.
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person_str_mv Roriz, Custódio Lobo
Roriz, Custódio Lobo
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Dias, Maria Inês
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Reis, Filipa S.
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Pires, Tânia C.S.
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Alves, Maria José
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Fernandes, Filipa A.
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Morales, Patricia
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spelling engpt_PTBetalains are a group of secondary metabolites named chromoalkaloids that are synthesized from tyrosine. These compounds have gained some attention in the last few years mainly due to their interesting bioactive potential, namely antioxidant, antimicrobial, and other bioactive properties [1]. Their strong and vibrant colours are also one of the characteristics by which these compounds have gained visibility in the food and pharmaceutical industries [2]. Betalains can be divided in two groups regarding the colour range: betaxanthins in the orange to yellow range, and betacyanins in the purple to pink range. Thereby, these compounds can be used as natural colouring agents, providing alternatives to the massively used artificial counterparts [3]. Although there are already some natural options in the market, these are not enough to meet the needs of the food industry, due to the growing concern of consumers regarding what they eat. Thus, the objectives of this work were to: i) obtain bioactive extracts and with strong colouring capacity from the epicarp of two pitaya varieties, white-fleshed pitaya Hylocereus undatus (Haworth) Britton & Rose (WFP) and red-fleshed pitaya Hylocereus costaricensis (F.A.C.Weber) Britton & Rose (RFP); ii) chemically characterize the betalains’ content through HPLC-DAD-ESI/MS; iii) evaluate the bioactive properties of the extracts, namely antimicrobial activity. The extracts were obtained through a dynamic maceration assisted by heat, and the betacyanins’ profile was characterized by HPLC-DAD-ESI/MS. The antibacterial capacity was determined against a panel of Gram-negative and Gram-positive bacteria using the colorimetric method of rapid detection with p-iodonitrotetrazolium chloride (INT), and the responses obtained were expressed as minimum inhibitory (MIC) and minimum bactericidal (MBC) concentrations. By the chromatographic analysis of the extracts it was possible to identify six compounds in both samples. For the WFP the major compounds identified were 6'-O-malonylbetanin (phylocactin), followed by 4'-malonyl-betanin, while for the RFP the major compound found was phylocactin. In the evaluation of the antibacterial activity, both extracts showed MIC and MBC values that ranged from 10 to 20 mg/mL. Gram-positive bacteria showed to be more susceptible to both extracts then the negative strains. Further studies need to be conducted to better understand the correlation between the bioactive potential and the betacyanins’ composition. Nevertheless, these natural matrixes proved to be viable alternatives for obtaining colouring extracts with antimicrobial properties.application/pdfpt_PTDragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacityPersonalRoriz, Custódio LoboDSpacehttp://dspace.org/items/d13ab9dd-af85-4652-bae4-88b2a9034d79DSpacehttp://dspace.org/items/d13ab9dd-af85-4652-bae4-88b2a9034d79RorizCustódio LoboCiência IDhttps://www.ciencia-id.pt9519-D97C-6B17ORCIDhttp://orcid.org0000-0002-4021-1078Scopus Author IDhttps://www.scopus.com56151637600PersonalDias, Maria InêsDSpacehttp://dspace.org/items/7ca8432b-e7f4-4116-a56e-9eba0d4403bdDSpacehttp://dspace.org/items/7ca8432b-e7f4-4116-a56e-9eba0d4403bdDiasMaria InêsCiência IDhttps://www.ciencia-id.pt2A13-4BE6-C7CFORCIDhttp://orcid.org0000-0001-8744-7814Researcher IDhttps://www.researcherid.comM-8242-2013Scopus Author IDhttps://www.scopus.com54388787000PersonalReis, Filipa S.DSpacehttp://dspace.org/items/b8d384ae-2134-4735-93a6-0d2febbf9220DSpacehttp://dspace.org/items/b8d384ae-2134-4735-93a6-0d2febbf9220ReisFilipa S.Ciência IDhttps://www.ciencia-id.pt391F-AFE1-64C7ORCIDhttp://orcid.org0000-0002-9159-0530Researcher IDhttps://www.researcherid.comI-2093-2013Scopus Author IDhttps://www.scopus.com36982144400PersonalPires, Tânia C.S.DSpacehttp://dspace.org/items/34af4d18-b8ae-4329-9450-69dc35ed448fDSpacehttp://dspace.org/items/34af4d18-b8ae-4329-9450-69dc35ed448fPiresTânia C.S.P.Ciência IDhttps://www.ciencia-id.pt321E-2D96-00CAORCIDhttp://orcid.org0000-0002-3954-3833Researcher IDhttps://www.researcherid.comQ-2842-2018Scopus Author IDhttps://www.scopus.com57057440000PersonalAlves, Maria JoséDSpacehttp://dspace.org/items/7850f8c2-8834-4d5a-b4a7-df482abd76d3DSpacehttp://dspace.org/items/7850f8c2-8834-4d5a-b4a7-df482abd76d3AlvesMaria JoséCiência IDhttps://www.ciencia-id.ptD618-B3A9-D312ORCIDhttp://orcid.org0000-0001-8506-4393Researcher IDhttps://www.researcherid.comM-6624-2016Scopus Author IDhttps://www.scopus.com16400584800PersonalFernandes, Filipa A.DSpacehttp://dspace.org/items/95f2a15c-591c-44b9-bcc3-dfdf49c6af26DSpacehttp://dspace.org/items/95f2a15c-591c-44b9-bcc3-dfdf49c6af26FernandesFilipa AlexandraCiência IDhttps://www.ciencia-id.pt2A1F-9985-F38BORCIDhttp://orcid.org0000-0001-6807-1137Researcher IDhttps://www.researcherid.comA-8045-2019Morales, PatriciaPersonalBarros, LillianDSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01DSpacehttp://dspace.org/items/3af07ffe-f914-48ba-a5d5-efcf70fdce01BarrosLillianCiência IDhttps://www.ciencia-id.pt9616-35CB-D001ORCIDhttp://orcid.org0000-0002-9050-5189Researcher IDhttps://www.researcherid.comJ-3600-2013Researcher IDhttps://www.researcherid.comJ-3600-2013Scopus Author IDhttps://www.scopus.com35236343600Scopus Author IDhttps://www.scopus.com57194900801PersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISBNIsPartOf978-989-8124-26-52019-06-19T15:05:21Z20192019-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/19353http://purl.org/coar/access_right/c_abf2open accessDragon fruits1405945 bytesFundação para a Ciência e a TecnologiaMountain Research Centre6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaDevelopment of a new colouring agent from Gomphrena globosa L.: optimization of the extraction process, stability studies and proof-of-concept in a food matrixPOR_NORTECrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaBio-based coloring agents for food applications: a “biorefinery” approach from the bio-waste of blueberry fruits and edible petalsPOR_NORTECrossref Funder IDhttp://doi.org/10.13039/501100001871other research producthttp://purl.org/coar/resource_type/c_c94fconference object2019http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/a92a3054-7bf8-498d-9a38-990f5842b7d9/downloadXX EuroFoodChem ConferencePorto, Portugal
spellingShingle Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
Roriz, Custódio Lobo
Dragon fruits
status SINGLETON
subject.fl_str_mv Dragon fruits
title Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
title_full Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
title_fullStr Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
title_full_unstemmed Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
title_short Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
title_sort Dragon fruits as an alternative source of colorants: evaluation of antibacterial activity and colouring capacity
topic Dragon fruits
topic_facet Dragon fruits
url http://hdl.handle.net/10198/19353
visible 1