Publicação
Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed
| Resumo: | This study aimed to investigate the effect of extraction methods and solvents (Soxhlet and supercritical fluid extraction, SFE) on the chemical profile (gas chromatography [GC]/mass spectrometry and GC/flame ionization detection) and antimicrobial, antioxidant, antitumor, and anti-inflammatory activities of quinoa Piabiru (QP) husk crude extracts. Soxhlet was applied using 100% water (QPSH2O), and ethanolic solutions of 50% ethanol (ethanol:water 50:50 v/v, QPSetOH50), 70% ethanol (QPSetOH70), and 99% ethanol (QPSetOH99) as solvents. SFE was applied using CO2 and n-propane as solvents (QPSF). QPSH2O extract showed a higher concentration of phytosterols (stigmasterol, β-sitosterol, 7,8-epoxylanostan-11-OL,3-acetoxy) and carotenoids (rhodopin) and oleic acid, displaying intermediate thiobarbituric acid reactive substance (TBARS) antioxidant activity. Intermediate concentrations of ethanol (QPSetOH50 and QPSetOH70 extracts) increased the extraction yields and the antibacterial activity of the extracts (Pseudomonas aeruginosa, Salmonella enterica, Bacillus cereus, and Staphylococcus aureus). Higher concentrations of ethanol (QPSetOH99 extract) contributed to increased antioxidant activity as assessed by TBARS and higher recoveries of 4-(allyloxy)-2-methyl-2-pentanol, nonadecane, and lauric, myristic, palmitic, linoleic, stearic, arachidic, behenic, and lignoceric acids. Finally, the QPSF extract presented higher antioxidant activity by DPPH, ABTS, and ferric-reducing antioxidant power, higher content of 5-methoxy-2-pentanone, 5-methoxy-2-methyl- 2-pentanol, 1-(1,3-dimethylbutoxy)-2-propanol, oxalic, undecanoic, myristoleic, tricosanoic, pentadecanoic, elaidic, 11-eicosenoic, and erucic acids, and better antifungal activity against Aspergillus brasiliensis than the other extracts. Crude extracts were not cytotoxic against non-tumor cells (Vero) and did not show antitumor or antiinflammatory activities. Thus, antagonistic or synergistic effects of the phytochemical profile of quinoa husk crude extracts may present potential food and pharmaceutical applications. Practical Applications: The exceptional nutritional properties of quinoa seeds have boosted their cultivation in more than 123 countries. However, quinoa husks are generally considered waste. This study, which is of utmost importance, demonstrates the potential of extracting bioactive compounds from quinoa husks via pressurized fluids, turning them into a health-promoting co-product. This approach could minimize the current shortage of new antibiotics, antifungals, antitumor agents, and anti-inflammatory substances in the pharmaceutical and food sectors. By converting quinoa husks into valuable bioactive extracts,we contribute significantly to developing effective natural compounds, underlining the significance of our collective work. |
|---|---|
| Autores principais: | Casalvara, Rhaira Fernanda Ayoub |
| Outros Autores: | Santos, Everton da Silva; Mattos, Jose Vinicius; Pimentel, Tatiana Colombo; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Rodrigues, Daniele Bobrowski; Pereira, Carla; Corrêa, Rúbia C.G.; Cardozo‐Filho, Lucio; Gonçalves, José Eduardo |
| Assunto: | Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| Ano: | 2024 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1867172805368348672 |
|---|---|
| author | Casalvara, Rhaira Fernanda Ayoub |
| author2 | Santos, Everton da Silva Mattos, Jose Vinicius Pimentel, Tatiana Colombo Calhelha, Ricardo C. Pires, Tânia C.S.P. Rodrigues, Daniele Bobrowski Pereira, Carla Corrêa, Rúbia C.G. Cardozo‐Filho, Lucio Gonçalves, José Eduardo |
| author2_role | author author author author author author author author author author |
| author_facet | Casalvara, Rhaira Fernanda Ayoub Santos, Everton da Silva Mattos, Jose Vinicius Pimentel, Tatiana Colombo Calhelha, Ricardo C. Pires, Tânia C.S.P. Rodrigues, Daniele Bobrowski Pereira, Carla Corrêa, Rúbia C.G. Cardozo‐Filho, Lucio Gonçalves, José Eduardo |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Casalvara, Rhaira Fernanda Ayoub\"},{\"Person.name\":\"Santos, Everton da Silva\"},{\"Person.name\":\"Mattos, Jose Vinicius\"},{\"Person.name\":\"Pimentel, Tatiana Colombo\"},{\"Person.name\":\"Calhelha, Ricardo C.\",\"Person.identifier.orcid\":\"0000-0002-6801-4578\"},{\"Person.name\":\"Pires, Tânia C.S.P.\",\"Person.identifier.orcid\":\"0000-0002-3954-3833\"},{\"Person.name\":\"Rodrigues, Daniele Bobrowski\",\"Person.identifier.orcid\":\"0000-0003-0260-5751\"},{\"Person.name\":\"Pereira, Carla\",\"Person.identifier.orcid\":\"0000-0003-0093-771X\"},{\"Person.name\":\"Corrêa, Rúbia C.G.\"},{\"Person.name\":\"Cardozo‐Filho, Lucio\"},{\"Person.name\":\"Gonçalves, José Eduardo\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Casalvara, Rhaira Fernanda Ayoub Santos, Everton da Silva Mattos, Jose Vinicius Pimentel, Tatiana Colombo Calhelha, Ricardo C. Pires, Tânia C.S.P. Rodrigues, Daniele Bobrowski Pereira, Carla Corrêa, Rúbia C.G. Cardozo‐Filho, Lucio Gonçalves, José Eduardo |
| datacite.date.Accepted.fl_str_mv | 2024-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2024-10-09T09:06:45Z |
| datacite.date.embargoed.fl_str_mv | 2024-10-09T09:06:45Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| datacite.titles.title.fl_str_mv | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Casalvara, Rhaira Fernanda Ayoub Santos, Everton da Silva Mattos, Jose Vinicius Pimentel, Tatiana Colombo Calhelha, Ricardo C. Pires, Tânia C.S.P. Rodrigues, Daniele Bobrowski Pereira, Carla Corrêa, Rúbia C.G. Cardozo‐Filho, Lucio Gonçalves, José Eduardo |
| dc.date.Accepted.fl_str_mv | 2024-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2024-10-09T09:06:45Z |
| dc.date.embargoed.fl_str_mv | 2024-10-09T09:06:45Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/30392 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Wiley |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| dc.title.fl_str_mv | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | This study aimed to investigate the effect of extraction methods and solvents (Soxhlet and supercritical fluid extraction, SFE) on the chemical profile (gas chromatography [GC]/mass spectrometry and GC/flame ionization detection) and antimicrobial, antioxidant, antitumor, and anti-inflammatory activities of quinoa Piabiru (QP) husk crude extracts. Soxhlet was applied using 100% water (QPSH2O), and ethanolic solutions of 50% ethanol (ethanol:water 50:50 v/v, QPSetOH50), 70% ethanol (QPSetOH70), and 99% ethanol (QPSetOH99) as solvents. SFE was applied using CO2 and n-propane as solvents (QPSF). QPSH2O extract showed a higher concentration of phytosterols (stigmasterol, β-sitosterol, 7,8-epoxylanostan-11-OL,3-acetoxy) and carotenoids (rhodopin) and oleic acid, displaying intermediate thiobarbituric acid reactive substance (TBARS) antioxidant activity. Intermediate concentrations of ethanol (QPSetOH50 and QPSetOH70 extracts) increased the extraction yields and the antibacterial activity of the extracts (Pseudomonas aeruginosa, Salmonella enterica, Bacillus cereus, and Staphylococcus aureus). Higher concentrations of ethanol (QPSetOH99 extract) contributed to increased antioxidant activity as assessed by TBARS and higher recoveries of 4-(allyloxy)-2-methyl-2-pentanol, nonadecane, and lauric, myristic, palmitic, linoleic, stearic, arachidic, behenic, and lignoceric acids. Finally, the QPSF extract presented higher antioxidant activity by DPPH, ABTS, and ferric-reducing antioxidant power, higher content of 5-methoxy-2-pentanone, 5-methoxy-2-methyl- 2-pentanol, 1-(1,3-dimethylbutoxy)-2-propanol, oxalic, undecanoic, myristoleic, tricosanoic, pentadecanoic, elaidic, 11-eicosenoic, and erucic acids, and better antifungal activity against Aspergillus brasiliensis than the other extracts. Crude extracts were not cytotoxic against non-tumor cells (Vero) and did not show antitumor or antiinflammatory activities. Thus, antagonistic or synergistic effects of the phytochemical profile of quinoa husk crude extracts may present potential food and pharmaceutical applications. Practical Applications: The exceptional nutritional properties of quinoa seeds have boosted their cultivation in more than 123 countries. However, quinoa husks are generally considered waste. This study, which is of utmost importance, demonstrates the potential of extracting bioactive compounds from quinoa husks via pressurized fluids, turning them into a health-promoting co-product. This approach could minimize the current shortage of new antibiotics, antifungals, antitumor agents, and anti-inflammatory substances in the pharmaceutical and food sectors. By converting quinoa husks into valuable bioactive extracts,we contribute significantly to developing effective natural compounds, underlining the significance of our collective work. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://bibliotecadigital.ipb.pt/bitstreams/567ff4be-6dbe-4ae7-a953-3576f6a94094/download |
| funding.funder.alternateName_str_mv | FCT FCT FCT |
| funding.funder.identifier_str_mv | http://doi.org/10.13039/501100001871 http://doi.org/10.13039/501100001871 http://doi.org/10.13039/501100001871 |
| funding.funder.name_str_mv | Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia Fundação para a Ciência e a Tecnologia |
| funding.name_str_mv | 6817 - DCRRNI ID 6817 - DCRRNI ID 6817 - DCRRNI ID |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10198/30392 |
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| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
| network_acronym_str | ipb |
| network_name_str | Biblioteca Digital do IPB |
| oai_identifier_str | oai:bibliotecadigital.ipb.pt:10198/30392 |
| organization_str_mv | urn:organizationAcronym:ipb |
| person_str_mv | Casalvara, Rhaira Fernanda Ayoub Santos, Everton da Silva Mattos, Jose Vinicius Pimentel, Tatiana Colombo Calhelha, Ricardo C. Calhelha, Ricardo C. https://www.ciencia-id.pt/F313-E3CE-554E F313-E3CE-554E http://orcid.org/0000-0002-6801-4578 0000-0002-6801-4578 Pires, Tânia C.S.P. Pires, Tânia C.S.P. https://www.ciencia-id.pt/321E-2D96-00CA 321E-2D96-00CA http://orcid.org/0000-0002-3954-3833 0000-0002-3954-3833 Rodrigues, Daniele Bobrowski Rodrigues, Daniele Bobrowski https://www.ciencia-id.pt/A91B-FE1D-B275 A91B-FE1D-B275 http://orcid.org/0000-0003-0260-5751 0000-0003-0260-5751 Pereira, Carla Pereira, Carla https://www.ciencia-id.pt/EF10-2739-2B70 EF10-2739-2B70 http://orcid.org/0000-0003-0093-771X 0000-0003-0093-771X Corrêa, Rúbia C.G. Cardozo‐Filho, Lucio Gonçalves, José Eduardo |
| publishDate | 2024 |
| publisher.none.fl_str_mv | Wiley |
| reponame_str | Biblioteca Digital do IPB |
| repository_id_str | urn:repositoryAcronym:ipb |
| service_str_mv | urn:repositoryAcronym:ipb |
| spelling | engWileypt_PTThis study aimed to investigate the effect of extraction methods and solvents (Soxhlet and supercritical fluid extraction, SFE) on the chemical profile (gas chromatography [GC]/mass spectrometry and GC/flame ionization detection) and antimicrobial, antioxidant, antitumor, and anti-inflammatory activities of quinoa Piabiru (QP) husk crude extracts. Soxhlet was applied using 100% water (QPSH2O), and ethanolic solutions of 50% ethanol (ethanol:water 50:50 v/v, QPSetOH50), 70% ethanol (QPSetOH70), and 99% ethanol (QPSetOH99) as solvents. SFE was applied using CO2 and n-propane as solvents (QPSF). QPSH2O extract showed a higher concentration of phytosterols (stigmasterol, β-sitosterol, 7,8-epoxylanostan-11-OL,3-acetoxy) and carotenoids (rhodopin) and oleic acid, displaying intermediate thiobarbituric acid reactive substance (TBARS) antioxidant activity. Intermediate concentrations of ethanol (QPSetOH50 and QPSetOH70 extracts) increased the extraction yields and the antibacterial activity of the extracts (Pseudomonas aeruginosa, Salmonella enterica, Bacillus cereus, and Staphylococcus aureus). Higher concentrations of ethanol (QPSetOH99 extract) contributed to increased antioxidant activity as assessed by TBARS and higher recoveries of 4-(allyloxy)-2-methyl-2-pentanol, nonadecane, and lauric, myristic, palmitic, linoleic, stearic, arachidic, behenic, and lignoceric acids. Finally, the QPSF extract presented higher antioxidant activity by DPPH, ABTS, and ferric-reducing antioxidant power, higher content of 5-methoxy-2-pentanone, 5-methoxy-2-methyl- 2-pentanol, 1-(1,3-dimethylbutoxy)-2-propanol, oxalic, undecanoic, myristoleic, tricosanoic, pentadecanoic, elaidic, 11-eicosenoic, and erucic acids, and better antifungal activity against Aspergillus brasiliensis than the other extracts. Crude extracts were not cytotoxic against non-tumor cells (Vero) and did not show antitumor or antiinflammatory activities. Thus, antagonistic or synergistic effects of the phytochemical profile of quinoa husk crude extracts may present potential food and pharmaceutical applications. Practical Applications: The exceptional nutritional properties of quinoa seeds have boosted their cultivation in more than 123 countries. However, quinoa husks are generally considered waste. This study, which is of utmost importance, demonstrates the potential of extracting bioactive compounds from quinoa husks via pressurized fluids, turning them into a health-promoting co-product. This approach could minimize the current shortage of new antibiotics, antifungals, antitumor agents, and anti-inflammatory substances in the pharmaceutical and food sectors. By converting quinoa husks into valuable bioactive extracts,we contribute significantly to developing effective natural compounds, underlining the significance of our collective work.application/pdfpt_PTChemical profile and bioactivities of industrial wastes from Chenopodium quinoa seedCasalvara, Rhaira Fernanda AyoubSantos, Everton da SilvaMattos, Jose ViniciusPimentel, Tatiana ColomboPersonalCalhelha, Ricardo C.DSpacehttp://dspace.org/items/2d5d1a41-7561-4a01-871c-b4c97da35053DSpacehttp://dspace.org/items/2d5d1a41-7561-4a01-871c-b4c97da35053CalhelhaRicardo C.Ciência IDhttps://www.ciencia-id.ptF313-E3CE-554EORCIDhttp://orcid.org0000-0002-6801-4578Researcher IDhttps://www.researcherid.comJ-2172-2014Scopus Author IDhttps://www.scopus.com6507978333PersonalPires, Tânia C.S.P.DSpacehttp://dspace.org/items/34af4d18-b8ae-4329-9450-69dc35ed448fDSpacehttp://dspace.org/items/34af4d18-b8ae-4329-9450-69dc35ed448fPiresTânia C.S.P.Ciência IDhttps://www.ciencia-id.pt321E-2D96-00CAORCIDhttp://orcid.org0000-0002-3954-3833Researcher IDhttps://www.researcherid.comQ-2842-2018Scopus Author IDhttps://www.scopus.com57057440000PersonalRodrigues, Daniele BobrowskiDSpacehttp://dspace.org/items/18a661e9-0f77-4bd1-b2b0-5b929b760ab3DSpacehttp://dspace.org/items/18a661e9-0f77-4bd1-b2b0-5b929b760ab3RodriguesDaniele BobrowskiCiência IDhttps://www.ciencia-id.ptA91B-FE1D-B275ORCIDhttp://orcid.org0000-0003-0260-5751PersonalPereira, CarlaDSpacehttp://dspace.org/items/e07a8e12-52bb-47c5-bae7-41a5f648213bDSpacehttp://dspace.org/items/e07a8e12-52bb-47c5-bae7-41a5f648213bPereiraCarlaCiência IDhttps://www.ciencia-id.ptEF10-2739-2B70ORCIDhttp://orcid.org0000-0003-0093-771XResearcher IDhttps://www.researcherid.comK-1629-2016Scopus Author IDhttps://www.scopus.com55627876424Corrêa, Rúbia C.G.Cardozo‐Filho, LucioGonçalves, José EduardoHostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf1438-7697ISSNIsPartOf1438-9312DOIIsPartOf10.1002/ejlt.2024000212024-10-09T09:06:45Z20242024-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/30392http://purl.org/coar/access_right/c_abf2open accessExtraction methodsGreen chemistryIndustrial biowastePhytochemicalsQuinoa brasileira2566721 bytesFundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaMountain Research Center6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871Fundação para a Ciência e a TecnologiaAssociate Laboratory for Sustainability and Tecnology in Mountain Regions6817 - DCRRNI IDCrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal article2024http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/567ff4be-6dbe-4ae7-a953-3576f6a94094/downloadEuropean Journal of Lipid Science and Technology12610114 |
| spellingShingle | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed Casalvara, Rhaira Fernanda Ayoub Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| status | SINGLETON |
| subject.fl_str_mv | Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| title | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| title_full | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| title_fullStr | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| title_full_unstemmed | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| title_short | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| title_sort | Chemical profile and bioactivities of industrial wastes from Chenopodium quinoa seed |
| topic | Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| topic_facet | Extraction methods Green chemistry Industrial biowaste Phytochemicals Quinoa brasileira |
| url | http://hdl.handle.net/10198/30392 |
| visible | 1 |