Publicação
QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition
| Resumo: | Wild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. |
|---|---|
| Autores principais: | Froufe, Hugo J.C. |
| Outros Autores: | Abreu, Rui M.V.; Ferreira, Isabel C.F.R. |
| Assunto: | Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| Ano: | 2011 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Instituto Politécnico de Bragança |
| Idioma: | inglês |
| Origem: | Biblioteca Digital do IPB |
| _version_ | 1863851464248524800 |
|---|---|
| author | Froufe, Hugo J.C. |
| author2 | Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
| author2_role | author author |
| author_facet | Froufe, Hugo J.C. Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
| author_role | author |
| contributor_name_str_mv | Biblioteca Digital do IPB |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Froufe, Hugo J.C.\"},{\"Person.name\":\"Abreu, Rui M.V.\",\"Person.identifier.orcid\":\"0000-0002-7745-8015\"},{\"Person.name\":\"Ferreira, Isabel C.F.R.\",\"Person.identifier.orcid\":\"0000-0003-4910-4882\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Biblioteca Digital do IPB |
| datacite.creators.creator.creatorName.fl_str_mv | Froufe, Hugo J.C. Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
| datacite.date.Accepted.fl_str_mv | 2011-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2011-11-04T11:48:30Z |
| datacite.date.embargoed.fl_str_mv | 2011-11-04T11:48:30Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| datacite.subjects.subject.fl_str_mv | Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| datacite.titles.title.fl_str_mv | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| dc.contributor.none.fl_str_mv | Biblioteca Digital do IPB |
| dc.creator.none.fl_str_mv | Froufe, Hugo J.C. Abreu, Rui M.V. Ferreira, Isabel C.F.R. |
| dc.date.Accepted.fl_str_mv | 2011-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2011-11-04T11:48:30Z |
| dc.date.embargoed.fl_str_mv | 2011-11-04T11:48:30Z |
| dc.format.none.fl_str_mv | application/pdf application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10198/6271 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| dc.subject.none.fl_str_mv | Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| dc.title.fl_str_mv | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Wild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition. |
| dirty | 0 |
| eu_rights_str_mv | restrictedAccess |
| format | article |
| fulltext.url.fl_str_mv | https://bibliotecadigital.ipb.pt/bitstreams/d0a8cee3-8beb-4afa-b3d9-f7206b99116a/download |
| funding.funder.alternateName_str_mv | FCT |
| funding.funder.identifier_str_mv | http://doi.org/10.13039/501100001871 |
| funding.funder.name_str_mv | Fundação para a Ciência e a Tecnologia |
| funding.name_str_mv | 5876-PPCDTI |
| id | ipb_e7dc42e293e4c28ba883222a6eafeaca |
| identifier.url.fl_str_mv | http://hdl.handle.net/10198/6271 |
| instacron_str | ipb |
| institution | Instituto Politécnico de Bragança |
| instname_str | Instituto Politécnico de Bragança |
| language | eng |
| network_acronym_str | ipb |
| network_name_str | Biblioteca Digital do IPB |
| oai_identifier_str | oai:bibliotecadigital.ipb.pt:10198/6271 |
| organization_str_mv | urn:organizationAcronym:ipb |
| person_str_mv | Froufe, Hugo J.C. Abreu, Rui M.V. Abreu, Rui M.V. https://www.ciencia-id.pt/0F19-0DE2-12A2 0F19-0DE2-12A2 http://orcid.org/0000-0002-7745-8015 0000-0002-7745-8015 Ferreira, Isabel C.F.R. Ferreira, Isabel C.F.R. https://www.ciencia-id.pt/9418-CF95-9919 9418-CF95-9919 http://orcid.org/0000-0003-4910-4882 0000-0003-4910-4882 |
| publishDate | 2011 |
| publisher.none.fl_str_mv | Elsevier |
| reponame_str | Biblioteca Digital do IPB |
| repository_id_str | urn:repositoryAcronym:ipb |
| service_str_mv | urn:repositoryAcronym:ipb |
| spelling | engElsevierporWild mushrooms have become attractive as a source of physiologically beneficial compounds including antioxidants such as phenolic compounds and tocopherols. The concentrations of antioxidant compounds (phenolics and α-tocopherol) and EC50 values of antioxidant activity (concentration required to achieve 50% of radical scavenging activity and lipid peroxidation inhibition, or 0.5 of absorbance in reducing power) were analyzed by partial least square (PLS) regression analysis. Three QCAR (Quantitative Composition-Activity Relationship) models were constructed and their robustness and predictability were verified by internal and external cross-validation methods. Antioxidant activity correlated well with phenolics and -tocopherol contents, the major antioxidants in wild mushrooms. The models proved to be useful tools in the prediction of mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition.application/pdfapplication/pdfporQCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibitionFroufe, Hugo J.C.PersonalAbreu, Rui M.V.DSpacehttp://dspace.org/items/cadb03a4-5e60-4745-b35f-fc3a97c071bcDSpacehttp://dspace.org/items/cadb03a4-5e60-4745-b35f-fc3a97c071bcAbreuRui M.V.Ciência IDhttps://www.ciencia-id.pt0F19-0DE2-12A2ORCIDhttp://orcid.org0000-0002-7745-8015Scopus Author IDhttps://www.scopus.com7003290613PersonalFerreira, Isabel C.F.R.DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8DSpacehttp://dspace.org/items/bd0d1537-2e03-41fb-b27a-140af9c35db8FerreiraIsabel C.F.R.Ciência IDhttps://www.ciencia-id.pt9418-CF95-9919ORCIDhttp://orcid.org0000-0003-4910-4882Researcher IDhttps://www.researcherid.comE-8500-2013Scopus Author IDhttps://www.scopus.com36868826600HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf0169-7439DOIIsPartOf10.1016/j.chemolab.2011.09.0042011-11-04T11:48:30Z20112011-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/6271http://purl.org/coar/access_right/c_16ecrestricted accessWild mushroomsPhenolicsAlpha-tocopherolAntioxidant activityQCARPLS503469 bytes342612 bytesFundação para a Ciência e a TecnologiaPortuguese Wild Mushrooms: Chemical characterization and functional study of antiproliferative and proapoptotic properties in cancer cell lines5876-PPCDTICrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/d0a8cee3-8beb-4afa-b3d9-f7206b99116a/downloadhttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/7f3cdabb-d9aa-42c8-8e17-ca36fb6ec763/downloadChemometrics and Intelligent Laboratory Systems109(2)192196 |
| spellingShingle | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition Froufe, Hugo J.C. Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| subject.fl_str_mv | Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| title | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| title_full | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| title_fullStr | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| title_full_unstemmed | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| title_short | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| title_sort | QCAR models to predict wild mushrooms radical scavenging activity, reducing power and lipid peroxidation inhibition |
| topic | Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| topic_facet | Wild mushrooms Phenolics Alpha-tocopherol Antioxidant activity QCAR PLS |
| url | http://hdl.handle.net/10198/6271 |
| visible | 1 |