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Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment

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Resumo:Blood in large arteries may be treated as a homogenous fluid from a macroscopic prospective. However, in reality blood is a suspension of deformable cells in viscous fluid plasma. In microcirculation, which comprises the smallest arteries and veins, the flow behavior of individual blood cells and their interactions provide the microrheological basis of flow properties of blood at a macroscopic level. Hence, in microcirculation it is fundamental to study the flow behavior of blood at cellular level. Several studies on both individual and concentrated RBCs have already been performed in the past. However, all studies used conventional microscopes and also ghost cells to obtain visible trace RBCs through the microchannel. The present study is concerned in providing further insights into the microscale blood flow behavior through microchannels by applying an emerging optical technique known as confocal micro-PIV/PTV. The technique consists of a spinning disk confocal microscope, high speed camera and a diode-pumped solid state (DPSS) laser combined with a single particle tracking (SPT) software (MtrackJ). Detailed measurements on the motions of RBCs were measured at different haematocrits (Hct) and the correspondent radial dispersion coefficient was determined.
Autores principais:Lima, Rui A.
Outros Autores:Ishikawa, Takuji; Imai, Yohsuke; Fujiwara, Hiroki; Takeda, Motohiro; Matsuki, Noriaki; Wada, Shigeo; Yamaguchi, Takami
Assunto:Microcirculation RBC dispersion Micro-PTV Red blood cells
Ano:2008
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Lima, Rui A.
author2 Ishikawa, Takuji
Imai, Yohsuke
Fujiwara, Hiroki
Takeda, Motohiro
Matsuki, Noriaki
Wada, Shigeo
Yamaguchi, Takami
author2_role author
author
author
author
author
author
author
author_facet Lima, Rui A.
Ishikawa, Takuji
Imai, Yohsuke
Fujiwara, Hiroki
Takeda, Motohiro
Matsuki, Noriaki
Wada, Shigeo
Yamaguchi, Takami
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Lima, Rui A.\",\"Person.identifier.orcid\":\"0000-0003-3428-637X\"},{\"Person.name\":\"Ishikawa, Takuji\"},{\"Person.name\":\"Imai, Yohsuke\"},{\"Person.name\":\"Fujiwara, Hiroki\"},{\"Person.name\":\"Takeda, Motohiro\"},{\"Person.name\":\"Matsuki, Noriaki\"},{\"Person.name\":\"Wada, Shigeo\"},{\"Person.name\":\"Yamaguchi, Takami\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Lima, Rui A.
Ishikawa, Takuji
Imai, Yohsuke
Fujiwara, Hiroki
Takeda, Motohiro
Matsuki, Noriaki
Wada, Shigeo
Yamaguchi, Takami
datacite.date.Accepted.fl_str_mv 2008-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2010-02-19T10:18:50Z
datacite.date.embargoed.fl_str_mv 2010-02-19T10:18:50Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Microcirculation
RBC dispersion
Micro-PTV
Red blood cells
datacite.titles.title.fl_str_mv Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Lima, Rui A.
Ishikawa, Takuji
Imai, Yohsuke
Fujiwara, Hiroki
Takeda, Motohiro
Matsuki, Noriaki
Wada, Shigeo
Yamaguchi, Takami
dc.date.Accepted.fl_str_mv 2008-01-01T00:00:00Z
dc.date.available.fl_str_mv 2010-02-19T10:18:50Z
dc.date.embargoed.fl_str_mv 2010-02-19T10:18:50Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/2015
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv JSME
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Microcirculation
RBC dispersion
Micro-PTV
Red blood cells
dc.title.fl_str_mv Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_5794
description Blood in large arteries may be treated as a homogenous fluid from a macroscopic prospective. However, in reality blood is a suspension of deformable cells in viscous fluid plasma. In microcirculation, which comprises the smallest arteries and veins, the flow behavior of individual blood cells and their interactions provide the microrheological basis of flow properties of blood at a macroscopic level. Hence, in microcirculation it is fundamental to study the flow behavior of blood at cellular level. Several studies on both individual and concentrated RBCs have already been performed in the past. However, all studies used conventional microscopes and also ghost cells to obtain visible trace RBCs through the microchannel. The present study is concerned in providing further insights into the microscale blood flow behavior through microchannels by applying an emerging optical technique known as confocal micro-PIV/PTV. The technique consists of a spinning disk confocal microscope, high speed camera and a diode-pumped solid state (DPSS) laser combined with a single particle tracking (SPT) software (MtrackJ). Detailed measurements on the motions of RBCs were measured at different haematocrits (Hct) and the correspondent radial dispersion coefficient was determined.
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eu_rights_str_mv openAccess
format conferencePaper
fulltext.url.fl_str_mv https://bibliotecadigital.ipb.pt/bitstreams/7a99835b-2d99-444f-a788-ecaa4ae2a258/download
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instname_str Instituto Politécnico de Bragança
language eng
network_acronym_str ipb
network_name_str Biblioteca Digital do IPB
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/2015
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Lima, Rui A.
Lima, Rui A.
https://www.ciencia-id.pt/EE12-C3FB-349D
EE12-C3FB-349D
http://orcid.org/0000-0003-3428-637X
0000-0003-3428-637X
Ishikawa, Takuji
Imai, Yohsuke
Fujiwara, Hiroki
Takeda, Motohiro
Matsuki, Noriaki
Wada, Shigeo
Yamaguchi, Takami
publishDate 2008
publisher.none.fl_str_mv JSME
reponame_str Biblioteca Digital do IPB
repository_id_str urn:repositoryAcronym:ipb
service_str_mv urn:repositoryAcronym:ipb
spelling engJSMEptBlood in large arteries may be treated as a homogenous fluid from a macroscopic prospective. However, in reality blood is a suspension of deformable cells in viscous fluid plasma. In microcirculation, which comprises the smallest arteries and veins, the flow behavior of individual blood cells and their interactions provide the microrheological basis of flow properties of blood at a macroscopic level. Hence, in microcirculation it is fundamental to study the flow behavior of blood at cellular level. Several studies on both individual and concentrated RBCs have already been performed in the past. However, all studies used conventional microscopes and also ghost cells to obtain visible trace RBCs through the microchannel. The present study is concerned in providing further insights into the microscale blood flow behavior through microchannels by applying an emerging optical technique known as confocal micro-PIV/PTV. The technique consists of a spinning disk confocal microscope, high speed camera and a diode-pumped solid state (DPSS) laser combined with a single particle tracking (SPT) software (MtrackJ). Detailed measurements on the motions of RBCs were measured at different haematocrits (Hct) and the correspondent radial dispersion coefficient was determined.application/pdfptDispersion of red blood cells in microchannels : a confocal micro-PTV assessmentPersonalLima, Rui A.DSpacehttp://dspace.org/items/7b50c499-8095-4f4f-8b1b-fa7388e4ff62DSpacehttp://dspace.org/items/7b50c499-8095-4f4f-8b1b-fa7388e4ff62LimaRui A.Ciência IDhttps://www.ciencia-id.ptEE12-C3FB-349DORCIDhttp://orcid.org0000-0003-3428-637XResearcher IDhttps://www.researcherid.comH-5157-2016Scopus Author IDhttps://www.scopus.com18437397800Ishikawa, TakujiImai, YohsukeFujiwara, HirokiTakeda, MotohiroMatsuki, NoriakiWada, ShigeoYamaguchi, TakamiHostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.pt2010-02-19T10:18:50Z20082008-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/2015http://purl.org/coar/access_right/c_abf2open accessMicrocirculationRBC dispersionMicro-PTVRed blood cells267431 bytesother research producthttp://purl.org/coar/resource_type/c_5794conference paperhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/7a99835b-2d99-444f-a788-ecaa4ae2a258/download20th Bioengineering ConferenceTokyo, Japan
spellingShingle Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
Lima, Rui A.
Microcirculation
RBC dispersion
Micro-PTV
Red blood cells
status SINGLETON
subject.fl_str_mv Microcirculation
RBC dispersion
Micro-PTV
Red blood cells
title Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
title_full Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
title_fullStr Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
title_full_unstemmed Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
title_short Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
title_sort Dispersion of red blood cells in microchannels : a confocal micro-PTV assessment
topic Microcirculation
RBC dispersion
Micro-PTV
Red blood cells
topic_facet Microcirculation
RBC dispersion
Micro-PTV
Red blood cells
url http://hdl.handle.net/10198/2015
visible 1