Publicação
Oxidative stress in relation to aging and exercise
| Resumo: | Definition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age. |
|---|---|
| Autores principais: | Verhaegen, Dimphna |
| Outros Autores: | Smits, Kelly; Osório, Nádia; Caseiro, Armando |
| Assunto: | Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Instituto Politécnico de Coimbra |
| Idioma: | inglês |
| Origem: | Instituto Politécnico de Coimbra |
| _version_ | 1864243955687751680 |
|---|---|
| author | Verhaegen, Dimphna |
| author2 | Smits, Kelly Osório, Nádia Caseiro, Armando |
| author2_role | author author author |
| author_facet | Verhaegen, Dimphna Smits, Kelly Osório, Nádia Caseiro, Armando |
| author_role | author |
| contributor_name_str_mv | Repositório Comum |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Verhaegen, Dimphna\"},{\"Person.name\":\"Smits, Kelly\"},{\"Person.name\":\"Osório, Nádia\",\"Person.identifier.orcid\":\"0000-0001-9559-2165\"},{\"Person.name\":\"Caseiro, Armando\",\"Person.identifier.orcid\":\"0000-0001-7844-0506\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Comum |
| datacite.creators.creator.creatorName.fl_str_mv | Verhaegen, Dimphna Smits, Kelly Osório, Nádia Caseiro, Armando |
| datacite.date.Accepted.fl_str_mv | 2022-08-25T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-04-28T15:56:16Z |
| datacite.date.embargoed.fl_str_mv | 2023-04-28T15:56:16Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| datacite.titles.title.fl_str_mv | Oxidative stress in relation to aging and exercise |
| dc.contributor.none.fl_str_mv | Repositório Comum |
| dc.creator.none.fl_str_mv | Verhaegen, Dimphna Smits, Kelly Osório, Nádia Caseiro, Armando |
| dc.date.Accepted.fl_str_mv | 2022-08-25T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-04-28T15:56:16Z |
| dc.date.embargoed.fl_str_mv | 2023-04-28T15:56:16Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.26/44676 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | MDPI |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by-nc-sa/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| dc.title.fl_str_mv | Oxidative stress in relation to aging and exercise |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Definition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://comum.rcaap.pt/bitstreams/42260005-0a76-47e6-8b80-60dd9ccf7d5c/download |
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| identifier.url.fl_str_mv | http://hdl.handle.net/10400.26/44676 |
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| institution | Instituto Politécnico de Coimbra |
| instname_str | Instituto Politécnico de Coimbra |
| language | eng |
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| network_name_str | Instituto Politécnico de Coimbra |
| oai_identifier_str | oai:comum.rcaap.pt:10400.26/44676 |
| organization_str_mv | urn:organizationAcronym:ipc |
| person_str_mv | Verhaegen, Dimphna Smits, Kelly Osório, Nádia Osório, Nádia https://www.ciencia-id.pt/271E-2D9B-E7F3 271E-2D9B-E7F3 http://orcid.org/0000-0001-9559-2165 0000-0001-9559-2165 Caseiro, Armando Caseiro, Armando https://www.ciencia-id.pt/4012-A0D8-66D6 4012-A0D8-66D6 http://orcid.org/0000-0001-7844-0506 0000-0001-7844-0506 |
| publishDate | 2022 |
| publisher.none.fl_str_mv | MDPI |
| reponame_str | Instituto Politécnico de Coimbra |
| repository_id_str | urn:repositoryAcronym:ipc |
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| spelling | engMDPIpt_PTDefinition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age.application/pdfpt_PTOxidative stress in relation to aging and exerciseVerhaegen, DimphnaSmits, KellyPersonalOsório, NádiaDSpacehttp://dspace.org/items/f98c6cd7-be5f-4d66-bbf5-7ae3746e3d6bDSpacehttp://dspace.org/items/f98c6cd7-be5f-4d66-bbf5-7ae3746e3d6bOsórioNádiaCiência IDhttps://www.ciencia-id.pt271E-2D9B-E7F3ORCIDhttp://orcid.org0000-0001-9559-2165Scopus Author IDhttps://www.scopus.com57188973499Scopus Author IDhttps://www.scopus.com6601949009PersonalCaseiro, ArmandoDSpacehttp://dspace.org/items/3736a1f3-88d6-42fb-94fc-ecd5484412deDSpacehttp://dspace.org/items/3736a1f3-88d6-42fb-94fc-ecd5484412deCaseiroArmandoCiência IDhttps://www.ciencia-id.pt4012-A0D8-66D6ORCIDhttp://orcid.org0000-0001-7844-0506Researcher IDhttps://www.researcherid.comL-8385-2013Scopus Author IDhttps://www.scopus.com35738464000Scopus Author IDhttps://www.scopus.com57087329800HostingInstitutionOrganizationalRepositório Comume-mailmailto:comum@rcaap.ptcomum@rcaap.ptISSNIsPartOf2673-8392DOIIsPartOfhttps://doi.org/10.3390/ encyclopedia20301052023-04-28T15:56:16Z2022-08-252022-08-25T00:00:00ZHandlehttp://hdl.handle.net/10400.26/44676http://purl.org/coar/access_right/c_abf2open accessOxidative stressAgingExerciseGlutathioneSuperoxide dismutaseReactive oxygen speciesAntioxidantsCortisolStress oxidativoEnvelhecimentoExercício físicoSuperóxido dismutaseEspécies reativas de oxigénioAntioxidantesHidrocortisona978250 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2022-08-25http://creativecommons.org/licenses/by-nc-sa/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://comum.rcaap.pt/bitstreams/42260005-0a76-47e6-8b80-60dd9ccf7d5c/downloadEncyclopedia215451558Basel, Switzerland |
| spellingShingle | Oxidative stress in relation to aging and exercise Verhaegen, Dimphna Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| subject.fl_str_mv | Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| title | Oxidative stress in relation to aging and exercise |
| title_full | Oxidative stress in relation to aging and exercise |
| title_fullStr | Oxidative stress in relation to aging and exercise |
| title_full_unstemmed | Oxidative stress in relation to aging and exercise |
| title_short | Oxidative stress in relation to aging and exercise |
| title_sort | Oxidative stress in relation to aging and exercise |
| topic | Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| topic_facet | Oxidative stress Aging Exercise Glutathione Superoxide dismutase Reactive oxygen species Antioxidants Cortisol Stress oxidativo Envelhecimento Exercício físico Superóxido dismutase Espécies reativas de oxigénio Antioxidantes Hidrocortisona |
| url | http://hdl.handle.net/10400.26/44676 |
| visible | 1 |