Detalhes bibliográficos
| Resumo: | The ovarian cystic teratoma is a rare cause of autoimmune haemolytic anaemia by warm antibodies, resistant to corticotherapy, with few case reports published in the medical literature. We present a case of a 45-year-old woman admitted to hospital due to general weakness. Laboratory studies revealed macrocytic anaemia, biochemical parameters of haemolysis and peripheral spherocytosis. The direct Coombs test was positive. Viral serologies, anti-nuclear antibodies, anti-double-stranded DNA antibodies and β2-microglobulin were negative. CT scan of the thorax, abdomen and pelvis showed a heterogeneous right anexial lesion. The patient was treated with corticotherapy without improvement of anaemia. Regression of extra-vascular haemolysis and normalisation of haemoglobin was obtained only after laparoscopic splenectomy and right ooforectomy, and the histopathology of the right anexial mass revealed a cystic teratoma. Previously published cases controlled the haemolysis by surgically removing the lesion associated with splenectomy. |
| Autores principais: | Raimundo, P |
| Outros Autores: | Coelho, S; Cabeleira, A; Dias, L; Gonçalves, M |
| Assunto: | HSJ MED HSJ ANPAT HSJ CIR Anemia, Hemolytic, Autoimmune/immunology Coombs Test Diagnosis, Differential Laparoscopy Ovarian Neoplasms/diagnosis Ovarian Neoplasms/immunology Ovarian Neoplasms/surgery Ovariectomy Splenectomy Teratoma/diagnosis Teratoma/immunology Teratoma/surgery Tomography, X-Ray Computed |
| Ano: | 2010 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Centro Hospitalar de Lisboa Central, EPE (CHLC) |
| Idioma: | inglês |
| Origem: | Repositório do Centro Hospitalar de Lisboa Central, EPE |