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The Role of Bone Biopsy in the Management of CKD-MBD

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Resumo:A bone biopsy is still considered the gold standard for diagnosis of renal osteodystrophy. It allows to measure both static and dynamic parameters of bone remodeling and is the only method able to evaluate mineralization and allows analysis of both cortical and trabecular bone. Although bone volume can be measured indirectly by dual-energy X-ray absorptiometry, mineralization defects, bone metal deposits, cellular number/activity, and even turnover abnormalities are difficult to determine by techniques other than qualitative bone histomorphometry. In this review, we evaluate the role of bone biopsy in the clinical practice.
Autores principais:Ferreira, AC
Outros Autores:Cohen-Solal, M; D’Haese, PC; Ferreira, A
Assunto:Bone histomorphometry Bone histomorphometry Renal osteodystrophy HCC NEF
Ano:2021
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Centro Hospitalar de Lisboa Central, EPE (CHLC)
Idioma:inglês
Origem:Repositório do Centro Hospitalar de Lisboa Central, EPE
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author Ferreira, AC
author2 Cohen-Solal, M
D’Haese, PC
Ferreira, A
author2_role author
author
author
author_facet Ferreira, AC
Ferreira, AC
Cohen-Solal, M
D’Haese, PC
Ferreira, A
Cohen-Solal, M
D’Haese, PC
Ferreira, A
author_role author
contributor_name_str_mv Repositório da Unidade Local de Saúde São José
country_str PT
creators_json_str [{\"Person.name\":\"Ferreira, AC\"},{\"Person.name\":\"Cohen-Solal, M\"},{\"Person.name\":\"D’Haese, PC\"},{\"Person.name\":\"Ferreira, A\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Repositório da Unidade Local de Saúde São José
datacite.creators.creator.creatorName.fl_str_mv Ferreira, AC
Cohen-Solal, M
D’Haese, PC
Ferreira, A
datacite.date.Accepted.fl_str_mv 2021-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2022-12-06T12:49:35Z
datacite.date.embargoed.fl_str_mv 2022-12-06T12:49:35Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
datacite.titles.title.fl_str_mv The Role of Bone Biopsy in the Management of CKD-MBD
dc.contributor.none.fl_str_mv Repositório da Unidade Local de Saúde São José
dc.creator.none.fl_str_mv Ferreira, AC
Cohen-Solal, M
D’Haese, PC
Ferreira, A
dc.date.Accepted.fl_str_mv 2021-01-01T00:00:00Z
dc.date.available.fl_str_mv 2022-12-06T12:49:35Z
dc.date.embargoed.fl_str_mv 2022-12-06T12:49:35Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10400.17/4294
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Springerlink
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
dc.title.fl_str_mv The Role of Bone Biopsy in the Management of CKD-MBD
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description A bone biopsy is still considered the gold standard for diagnosis of renal osteodystrophy. It allows to measure both static and dynamic parameters of bone remodeling and is the only method able to evaluate mineralization and allows analysis of both cortical and trabecular bone. Although bone volume can be measured indirectly by dual-energy X-ray absorptiometry, mineralization defects, bone metal deposits, cellular number/activity, and even turnover abnormalities are difficult to determine by techniques other than qualitative bone histomorphometry. In this review, we evaluate the role of bone biopsy in the clinical practice.
dirty 0
eu_rights_str_mv openAccess
format article
fulltext.url.fl_str_mv https://repositorio.chlc.pt/bitstreams/589e9337-d485-4bf1-af49-5f9cd09f9111/download
id rchlc_a2f33d5dcd99e448da5ab82873ea49e4
identifier.url.fl_str_mv http://hdl.handle.net/10400.17/4294
instacron_str chlc
institution Centro Hospitalar de Lisboa Central, EPE (CHLC)
instname_str Centro Hospitalar de Lisboa Central, EPE (CHLC)
language eng
network_acronym_str rchlc
network_name_str Repositório do Centro Hospitalar de Lisboa Central, EPE
oai_identifier_str oai:repositorio.chlc.pt:10400.17/4294
organization_str_mv urn:organizationAcronym:chlc
person_str_mv Ferreira, AC
Cohen-Solal, M
D’Haese, PC
Ferreira, A
publishDate 2021
publisher.none.fl_str_mv Springerlink
reponame_str Repositório do Centro Hospitalar de Lisboa Central, EPE
repository_id_str urn:repositoryAcronym:rchlc
service_str_mv urn:repositoryAcronym:rchlc
spelling engSpringerlinkpt_PTA bone biopsy is still considered the gold standard for diagnosis of renal osteodystrophy. It allows to measure both static and dynamic parameters of bone remodeling and is the only method able to evaluate mineralization and allows analysis of both cortical and trabecular bone. Although bone volume can be measured indirectly by dual-energy X-ray absorptiometry, mineralization defects, bone metal deposits, cellular number/activity, and even turnover abnormalities are difficult to determine by techniques other than qualitative bone histomorphometry. In this review, we evaluate the role of bone biopsy in the clinical practice.application/pdfpt_PTThe Role of Bone Biopsy in the Management of CKD-MBDFerreira, ACCohen-Solal, MD’Haese, PCFerreira, AHostingInstitutionOrganizationalRepositório da Unidade Local de Saúde São Josée-mailmailto:repositorio@ulssjose.min-saude.ptrepositorio@ulssjose.min-saude.ptDOIIsPartOf10.1007/s00223-021-00838-z2022-12-06T12:49:35Z20212021-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.17/4294http://purl.org/coar/access_right/c_abf2open accessBone histomorphometryBone histomorphometryRenal osteodystrophyHCC NEF607079 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.chlc.pt/bitstreams/589e9337-d485-4bf1-af49-5f9cd09f9111/downloadCalcified Tissue International1084528538
spellingShingle The Role of Bone Biopsy in the Management of CKD-MBD
The Role of Bone Biopsy in the Management of CKD-MBD
Ferreira, AC
Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
Ferreira, AC
Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
status NEW
subject.fl_str_mv Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
title The Role of Bone Biopsy in the Management of CKD-MBD
title_full The Role of Bone Biopsy in the Management of CKD-MBD
title_fullStr The Role of Bone Biopsy in the Management of CKD-MBD
The Role of Bone Biopsy in the Management of CKD-MBD
title_full_unstemmed The Role of Bone Biopsy in the Management of CKD-MBD
The Role of Bone Biopsy in the Management of CKD-MBD
title_short The Role of Bone Biopsy in the Management of CKD-MBD
title_sort The Role of Bone Biopsy in the Management of CKD-MBD
topic Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
topic_facet Bone histomorphometry
Bone histomorphometry
Renal osteodystrophy
HCC NEF
url http://hdl.handle.net/10400.17/4294
visible 1