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Trace element imbalances in hemodialysis patients: new data from a cohort of Portuguese patients

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Resumo:Patients with end-stage renal disease undergoing hemodialysis (HD) therapy are at risk of developing deficiencies of essential trace elements and/or overload of toxic trace elements, both of which may significantly affect their clinical status. Those imbalances may result from the disease itself but also from the therapy, namely the hemodialysis process. This work aimed at evaluate the current trace elements status in a cohort of patients under hemodialysis therapy. Serum (n=88) and whole blood samples (n=108) from HD patients, collected during the routine periodic control of Al levels, were analyzed for a wide panel of trace elements using inductively coupled plasma mass spectrometry (ICP-MS) (HD group). For comparison purposes, both serum (n=16) and whole blood samples (n=59) of individuals attending the same Clinical Laboratory but with no evidence of renal disease according to standard laboratory analytical criteria were also analysed (Control group).
Autores principais:Duro, Mary
Outros Autores:Azevedo, Rui; Costa, Félix; Pinto, Edgar; Almeida, Agostinho
Assunto:Hemodialysis patients
Ano:2022
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico do Porto
Idioma:inglês
Origem:Repositório Científico do Instituto Politécnico do Porto

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