Publicação
Long-term survival in multiple myeloma.
| Resumo: | KEY CLINICAL MESSAGE: The survival of multiple myeloma patients has improved very significantly over the last decade. Still median overall survival is inferior to 5 years. A small proportion of patients survive longer than 10 years. In this paper we discuss four cases illustrating the nonhomogeneous clinical presentation and evolution of this subset of patients. Surprisingly, these long survivors do not always have deep responses and some require frequent treatments, which include autologous stem cell transplantation and novel drugs. The authors discuss several aspects of these clinical histories, including treatment options, raising hypothesis on their relation with long survivorship which may be important to have in consideration when studying this subject. |
|---|---|
| Autores principais: | João, C |
| Outros Autores: | Costa, C; Coelho, I; Vergueiro, MJ; Ferreira, M; Silva, MG |
| Assunto: | Multiple myeloma Survival analysis Prognosis |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Hospital Prof. Dr. Fernando Fonseca E.P.E. |
| Idioma: | português |
| Origem: | Repositório do Hospital Prof. Doutor Fernando Fonseca |
| _version_ | 1868417267238174720 |
|---|---|
| author | João, C |
| author2 | Costa, C Coelho, I Vergueiro, MJ Ferreira, M Silva, MG |
| author2_role | author author author author author |
| author_facet | João, C Costa, C Coelho, I Vergueiro, MJ Ferreira, M Silva, MG |
| author_role | author |
| contributor_name_str_mv | Unidade Local de Saúde Amadora / Sintra |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"João, C\"},{\"Person.name\":\"Costa, C\"},{\"Person.name\":\"Coelho, I\"},{\"Person.name\":\"Vergueiro, MJ\"},{\"Person.name\":\"Ferreira, M\"},{\"Person.name\":\"Silva, MG\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Unidade Local de Saúde Amadora / Sintra |
| datacite.creators.creator.creatorName.fl_str_mv | João, C Costa, C Coelho, I Vergueiro, MJ Ferreira, M Silva, MG |
| datacite.date.Accepted.fl_str_mv | 2014-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2015-04-22T14:57:24Z |
| datacite.date.embargoed.fl_str_mv | 2015-04-22T14:57:24Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Multiple myeloma Survival analysis Prognosis |
| datacite.titles.title.fl_str_mv | Long-term survival in multiple myeloma. |
| dc.contributor.none.fl_str_mv | Unidade Local de Saúde Amadora / Sintra |
| dc.creator.none.fl_str_mv | João, C Costa, C Coelho, I Vergueiro, MJ Ferreira, M Silva, MG |
| dc.date.Accepted.fl_str_mv | 2014-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2015-04-22T14:57:24Z |
| dc.date.embargoed.fl_str_mv | 2015-04-22T14:57:24Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.10/1415 |
| dc.language.none.fl_str_mv | por |
| dc.publisher.none.fl_str_mv | John Wiley & Sons |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Multiple myeloma Survival analysis Prognosis |
| dc.title.fl_str_mv | Long-term survival in multiple myeloma. |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | KEY CLINICAL MESSAGE: The survival of multiple myeloma patients has improved very significantly over the last decade. Still median overall survival is inferior to 5 years. A small proportion of patients survive longer than 10 years. In this paper we discuss four cases illustrating the nonhomogeneous clinical presentation and evolution of this subset of patients. Surprisingly, these long survivors do not always have deep responses and some require frequent treatments, which include autologous stem cell transplantation and novel drugs. The authors discuss several aspects of these clinical histories, including treatment options, raising hypothesis on their relation with long survivorship which may be important to have in consideration when studying this subject. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.hff.min-saude.pt/bitstreams/b30c715b-3706-4c68-ba92-e135a9a1bdf4/download |
| id | rhff_120ca2bab3ba41d84dffccf8a4250e22 |
| identifier.url.fl_str_mv | http://hdl.handle.net/10400.10/1415 |
| instacron_str | hff |
| institution | Hospital Prof. Dr. Fernando Fonseca E.P.E. |
| instname_str | Hospital Prof. Dr. Fernando Fonseca E.P.E. |
| language | por |
| network_acronym_str | rhff |
| network_name_str | Repositório do Hospital Prof. Doutor Fernando Fonseca |
| oai_identifier_str | oai:repositorio.hff.min-saude.pt:10400.10/1415 |
| organization_str_mv | urn:organizationAcronym:hff |
| person_str_mv | João, C Costa, C Coelho, I Vergueiro, MJ Ferreira, M Silva, MG |
| publishDate | 2014 |
| publisher.none.fl_str_mv | John Wiley & Sons |
| reponame_str | Repositório do Hospital Prof. Doutor Fernando Fonseca |
| repository_id_str | urn:repositoryAcronym:rhff |
| service_str_mv | urn:repositoryAcronym:rhff |
| spelling | porJohn Wiley & SonsporKEY CLINICAL MESSAGE: The survival of multiple myeloma patients has improved very significantly over the last decade. Still median overall survival is inferior to 5 years. A small proportion of patients survive longer than 10 years. In this paper we discuss four cases illustrating the nonhomogeneous clinical presentation and evolution of this subset of patients. Surprisingly, these long survivors do not always have deep responses and some require frequent treatments, which include autologous stem cell transplantation and novel drugs. The authors discuss several aspects of these clinical histories, including treatment options, raising hypothesis on their relation with long survivorship which may be important to have in consideration when studying this subject.application/pdfporLong-term survival in multiple myeloma.João, CCosta, CCoelho, IVergueiro, MJFerreira, MSilva, MGHostingInstitutionOrganizationalUnidade Local de Saúde Amadora / Sintrae-mailmailto:repositorio@hff.min-saude.ptrepositorio@hff.min-saude.ptDOIIsPartOf10.1002/ccr3.762015-04-22T14:57:24Z20142014-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.10/1415http://purl.org/coar/access_right/c_abf2open accessMultiple myelomaSurvival analysisPrognosis75817 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.hff.min-saude.pt/bitstreams/b30c715b-3706-4c68-ba92-e135a9a1bdf4/downloadClinical case reports2173179Chichester |
| spellingShingle | Long-term survival in multiple myeloma. João, C Multiple myeloma Survival analysis Prognosis |
| status | SINGLETON |
| subject.fl_str_mv | Multiple myeloma Survival analysis Prognosis |
| title | Long-term survival in multiple myeloma. |
| title_full | Long-term survival in multiple myeloma. |
| title_fullStr | Long-term survival in multiple myeloma. |
| title_full_unstemmed | Long-term survival in multiple myeloma. |
| title_short | Long-term survival in multiple myeloma. |
| title_sort | Long-term survival in multiple myeloma. |
| topic | Multiple myeloma Survival analysis Prognosis |
| topic_facet | Multiple myeloma Survival analysis Prognosis |
| url | http://hdl.handle.net/10400.10/1415 |
| visible | 1 |