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Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia

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Resumo:OBJECTIVES: The aim of this study was to compare the applicability of the 1998 consensus diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD) with the recently proposed diagnostic criteria of the International bvFTD Criteria Consortium (FTDC). METHODS: We reviewed each individual item in the 1998 and FTDC criteria in 30 patients with bvFTD followed in a memory clinic (including 2 with the C9orf72 gene repeat expansion). RESULTS: All patients fulfilled the FTDC criteria (40% possible, 60% probable bvFTD) but only 66.7% fulfilled the 1998 criteria. One of the C9orf72 expansion carriers did not fulfill the 1998 criteria. This discordance was always due to the presence of exclusion features in the 1998 criteria, the most common being spatial disorientation and early severe amnesia. CONCLUSION: The new FTDC criteria are less restrictive and hence more sensitive for the diagnosis of bvFTD.
Autores principais:Costa, S
Outros Autores:Suárez-Calvet, M; Antón, S; Dols-Icardo, O; Clarimón, J; Alcolea, D; Fortea, J; Carmona, M; Sala, I; Sánchez-Saudinós, MB; Blesa, R; Lleó, A
Assunto:Frontotemporal dementia Differential diagnosis Demência frontotemporal Diagnóstico diferencial
Ano:2013
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Hospital Prof. Dr. Fernando Fonseca E.P.E.
Idioma:inglês
Origem:Repositório do Hospital Prof. Doutor Fernando Fonseca
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author Costa, S
author2 Suárez-Calvet, M
Antón, S
Dols-Icardo, O
Clarimón, J
Alcolea, D
Fortea, J
Carmona, M
Sala, I
Sánchez-Saudinós, MB
Blesa, R
Lleó, A
author2_role author
author
author
author
author
author
author
author
author
author
author
author_facet Costa, S
Suárez-Calvet, M
Antón, S
Dols-Icardo, O
Clarimón, J
Alcolea, D
Fortea, J
Carmona, M
Sala, I
Sánchez-Saudinós, MB
Blesa, R
Lleó, A
author_role author
contributor_name_str_mv Unidade Local de Saúde Amadora / Sintra
country_str PT
creators_json_txt [{\"Person.name\":\"Costa, S\"},{\"Person.name\":\"Suárez-Calvet, M\"},{\"Person.name\":\"Antón, S\"},{\"Person.name\":\"Dols-Icardo, O\"},{\"Person.name\":\"Clarimón, J\"},{\"Person.name\":\"Alcolea, D\"},{\"Person.name\":\"Fortea, J\"},{\"Person.name\":\"Carmona, M\"},{\"Person.name\":\"Sala, I\"},{\"Person.name\":\"Sánchez-Saudinós, MB\"},{\"Person.name\":\"Blesa, R\"},{\"Person.name\":\"Lleó, A\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Unidade Local de Saúde Amadora / Sintra
datacite.creators.creator.creatorName.fl_str_mv Costa, S
Suárez-Calvet, M
Antón, S
Dols-Icardo, O
Clarimón, J
Alcolea, D
Fortea, J
Carmona, M
Sala, I
Sánchez-Saudinós, MB
Blesa, R
Lleó, A
datacite.date.Accepted.fl_str_mv 2013-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2016-03-21T12:39:36Z
datacite.date.embargoed.fl_str_mv 2016-03-21T12:39:36Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Frontotemporal dementia
Differential diagnosis
Demência frontotemporal
Diagnóstico diferencial
datacite.titles.title.fl_str_mv Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
dc.contributor.none.fl_str_mv Unidade Local de Saúde Amadora / Sintra
dc.creator.none.fl_str_mv Costa, S
Suárez-Calvet, M
Antón, S
Dols-Icardo, O
Clarimón, J
Alcolea, D
Fortea, J
Carmona, M
Sala, I
Sánchez-Saudinós, MB
Blesa, R
Lleó, A
dc.date.Accepted.fl_str_mv 2013-01-01T00:00:00Z
dc.date.available.fl_str_mv 2016-03-21T12:39:36Z
dc.date.embargoed.fl_str_mv 2016-03-21T12:39:36Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10400.10/1575
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sage Publications
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Frontotemporal dementia
Differential diagnosis
Demência frontotemporal
Diagnóstico diferencial
dc.title.fl_str_mv Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description OBJECTIVES: The aim of this study was to compare the applicability of the 1998 consensus diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD) with the recently proposed diagnostic criteria of the International bvFTD Criteria Consortium (FTDC). METHODS: We reviewed each individual item in the 1998 and FTDC criteria in 30 patients with bvFTD followed in a memory clinic (including 2 with the C9orf72 gene repeat expansion). RESULTS: All patients fulfilled the FTDC criteria (40% possible, 60% probable bvFTD) but only 66.7% fulfilled the 1998 criteria. One of the C9orf72 expansion carriers did not fulfill the 1998 criteria. This discordance was always due to the presence of exclusion features in the 1998 criteria, the most common being spatial disorientation and early severe amnesia. CONCLUSION: The new FTDC criteria are less restrictive and hence more sensitive for the diagnosis of bvFTD.
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eu_rights_str_mv restrictedAccess
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fulltext.url.fl_str_mv https://repositorio.hff.min-saude.pt/bitstreams/ceac34ed-a53d-414c-8f88-aff0ac2704ca/download
id rhff_77ce676daa6c2621c8d9befd916c8d21
identifier.url.fl_str_mv http://hdl.handle.net/10400.10/1575
instacron_str hff
institution Hospital Prof. Dr. Fernando Fonseca E.P.E.
instname_str Hospital Prof. Dr. Fernando Fonseca E.P.E.
language eng
network_acronym_str rhff
network_name_str Repositório do Hospital Prof. Doutor Fernando Fonseca
oai_identifier_str oai:repositorio.hff.min-saude.pt:10400.10/1575
organization_str_mv urn:organizationAcronym:hff
person_str_mv Costa, S
Suárez-Calvet, M
Antón, S
Dols-Icardo, O
Clarimón, J
Alcolea, D
Fortea, J
Carmona, M
Sala, I
Sánchez-Saudinós, MB
Blesa, R
Lleó, A
publishDate 2013
publisher.none.fl_str_mv Sage Publications
reponame_str Repositório do Hospital Prof. Doutor Fernando Fonseca
repository_id_str urn:repositoryAcronym:rhff
service_str_mv urn:repositoryAcronym:rhff
spelling engSage Publicationspt_PTOBJECTIVES: The aim of this study was to compare the applicability of the 1998 consensus diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD) with the recently proposed diagnostic criteria of the International bvFTD Criteria Consortium (FTDC). METHODS: We reviewed each individual item in the 1998 and FTDC criteria in 30 patients with bvFTD followed in a memory clinic (including 2 with the C9orf72 gene repeat expansion). RESULTS: All patients fulfilled the FTDC criteria (40% possible, 60% probable bvFTD) but only 66.7% fulfilled the 1998 criteria. One of the C9orf72 expansion carriers did not fulfill the 1998 criteria. This discordance was always due to the presence of exclusion features in the 1998 criteria, the most common being spatial disorientation and early severe amnesia. CONCLUSION: The new FTDC criteria are less restrictive and hence more sensitive for the diagnosis of bvFTD.application/pdfpt_PTComparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementiaCosta, SSuárez-Calvet, MAntón, SDols-Icardo, OClarimón, JAlcolea, DFortea, JCarmona, MSala, ISánchez-Saudinós, MBBlesa, RLleó, AHostingInstitutionOrganizationalUnidade Local de Saúde Amadora / Sintrae-mailmailto:repositorio@hff.min-saude.ptrepositorio@hff.min-saude.ptISSNIsPartOf1938-2731DOIIsPartOf10.1177/15333175134889182016-03-21T12:39:36Z20132013-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.10/1575http://purl.org/coar/access_right/c_16ecrestricted accessFrontotemporal dementiaDifferential diagnosisDemência frontotemporalDiagnóstico diferencial230959 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.hff.min-saude.pt/bitstreams/ceac34ed-a53d-414c-8f88-aff0ac2704ca/downloadAmerican journal of Alzheimer's disease and other dementias28469476Thousand Oaks, Calif.
spellingShingle Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
Costa, S
Frontotemporal dementia
Differential diagnosis
Demência frontotemporal
Diagnóstico diferencial
status SINGLETON
subject.fl_str_mv Frontotemporal dementia
Differential diagnosis
Demência frontotemporal
Diagnóstico diferencial
title Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
title_full Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
title_fullStr Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
title_full_unstemmed Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
title_short Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
title_sort Comparison of 2 diagnostic criteria for the behavioral variant of frontotemporal dementia
topic Frontotemporal dementia
Differential diagnosis
Demência frontotemporal
Diagnóstico diferencial
topic_facet Frontotemporal dementia
Differential diagnosis
Demência frontotemporal
Diagnóstico diferencial
url http://hdl.handle.net/10400.10/1575
visible 1