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Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype

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Resumo:Euphorbia heterophylla is a weed species that invades extensive crop areas in subtropical regions of Brazil. This species was previously controlled by imazamox, but the continuous use of this herbicide has selected for resistant biotypes. Two biotypes of E. heterophylla from southern Brazil, one resistant (R) and one susceptible (S) to imazamox, were compared. The resistance of the R biotype was confrmed by dose-response assays since it required 1250.2g ai ha−1 to reduce the fresh weight by 50% versus 7.4g ai ha−1 for the S biotype. The acetolactate synthase (ALS) enzyme activity was studied using ALS-inhibiting herbicides from fve diferent chemical families. The R biotype required the highest concentrations to reduce this enzyme activity by 50%. A Ser653Asn mutation was found in the ALS gene of the R biotype. The experiments carried out showed that imazamox absorption and metabolism were not involved in resistance. However, greater 14C-imazamox root exudation was found in the R biotype (~70% of the total absorbed imazamox). Target site mutation in the ALS gene is the principal mechanism that explains the imazamox resistance of the R biotype, but root exudation seems to also contribute to the resistance of this biotype
Autores principais:Rojano-Blanco, Antonia
Outros Autores:Palma-Bautista, Candelario; Alcantara-de la Cruz, Ricardo; Torra, Joel; Alcantara, Esteban; De Prado, Rafael; Fernandes, João
Assunto:Euphorbia heterophylla Pest control Extensive crop areas Imazamox Controlo de infestantes Herbicida
Ano:2019
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Beja
Idioma:inglês
Origem:Repositório Institucional do IPBeja
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author Rojano-Blanco, Antonia
author2 Palma-Bautista, Candelario
Alcantara-de la Cruz, Ricardo
Torra, Joel
Alcantara, Esteban
De Prado, Rafael
Fernandes, João
author2_role author
author
author
author
author
author
author_facet Rojano-Blanco, Antonia
Palma-Bautista, Candelario
Alcantara-de la Cruz, Ricardo
Torra, Joel
Alcantara, Esteban
De Prado, Rafael
Fernandes, João
author_role author
country_str PT
creators_json_txt [{\"Person.name\":\"Rojano-Blanco, Antonia\"},{\"Person.name\":\"Palma-Bautista, Candelario\"},{\"Person.name\":\"Alcantara-de la Cruz, Ricardo\"},{\"Person.name\":\"Torra, Joel\"},{\"Person.name\":\"Alcantara, Esteban\"},{\"Person.name\":\"De Prado, Rafael\"},{\"Person.name\":\"Fernandes, João\"}]
datacite.creators.creator.creatorName.fl_str_mv Rojano-Blanco, Antonia
Palma-Bautista, Candelario
Alcantara-de la Cruz, Ricardo
Torra, Joel
Alcantara, Esteban
De Prado, Rafael
Fernandes, João
datacite.date.Accepted.fl_str_mv 2019-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2022-05-05T12:12:40Z
datacite.date.embargoed.fl_str_mv 2022-05-05T12:12:40Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Euphorbia heterophylla
Pest control
Extensive crop areas
Imazamox
Controlo de infestantes
Herbicida
datacite.titles.title.fl_str_mv Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
dc.creator.none.fl_str_mv Rojano-Blanco, Antonia
Palma-Bautista, Candelario
Alcantara-de la Cruz, Ricardo
Torra, Joel
Alcantara, Esteban
De Prado, Rafael
Fernandes, João
dc.date.Accepted.fl_str_mv 2019-01-01T00:00:00Z
dc.date.available.fl_str_mv 2022-05-05T12:12:40Z
dc.date.embargoed.fl_str_mv 2022-05-05T12:12:40Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12207/5424
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Nature
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Euphorbia heterophylla
Pest control
Extensive crop areas
Imazamox
Controlo de infestantes
Herbicida
dc.title.fl_str_mv Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Euphorbia heterophylla is a weed species that invades extensive crop areas in subtropical regions of Brazil. This species was previously controlled by imazamox, but the continuous use of this herbicide has selected for resistant biotypes. Two biotypes of E. heterophylla from southern Brazil, one resistant (R) and one susceptible (S) to imazamox, were compared. The resistance of the R biotype was confrmed by dose-response assays since it required 1250.2g ai ha−1 to reduce the fresh weight by 50% versus 7.4g ai ha−1 for the S biotype. The acetolactate synthase (ALS) enzyme activity was studied using ALS-inhibiting herbicides from fve diferent chemical families. The R biotype required the highest concentrations to reduce this enzyme activity by 50%. A Ser653Asn mutation was found in the ALS gene of the R biotype. The experiments carried out showed that imazamox absorption and metabolism were not involved in resistance. However, greater 14C-imazamox root exudation was found in the R biotype (~70% of the total absorbed imazamox). Target site mutation in the ALS gene is the principal mechanism that explains the imazamox resistance of the R biotype, but root exudation seems to also contribute to the resistance of this biotype
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inst_facet_str urn:organizationAcronym:ipb{{{_:::_}}}Instituto Politécnico de Beja
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oai_identifier_str oai:repositorio.ipbeja.pt:20.500.12207/5424
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Rojano-Blanco, Antonia
Palma-Bautista, Candelario
Alcantara-de la Cruz, Ricardo
Torra, Joel
Alcantara, Esteban
De Prado, Rafael
Fernandes, João
publishDate 2019
publisher.none.fl_str_mv Nature
repo_facet_str urn:repositoryAcronym:ripb{{{_:::_}}}Repositório Institucional do IPBeja
reponame_str Repositório Institucional do IPBeja
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spelling porEuphorbia heterophylla is a weed species that invades extensive crop areas in subtropical regions of Brazil. This species was previously controlled by imazamox, but the continuous use of this herbicide has selected for resistant biotypes. Two biotypes of E. heterophylla from southern Brazil, one resistant (R) and one susceptible (S) to imazamox, were compared. The resistance of the R biotype was confrmed by dose-response assays since it required 1250.2g ai ha−1 to reduce the fresh weight by 50% versus 7.4g ai ha−1 for the S biotype. The acetolactate synthase (ALS) enzyme activity was studied using ALS-inhibiting herbicides from fve diferent chemical families. The R biotype required the highest concentrations to reduce this enzyme activity by 50%. A Ser653Asn mutation was found in the ALS gene of the R biotype. The experiments carried out showed that imazamox absorption and metabolism were not involved in resistance. However, greater 14C-imazamox root exudation was found in the R biotype (~70% of the total absorbed imazamox). Target site mutation in the ALS gene is the principal mechanism that explains the imazamox resistance of the R biotype, but root exudation seems to also contribute to the resistance of this biotypeapplication/pdfengNatureporTarget site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotypeRojano-Blanco, AntoniaPalma-Bautista, CandelarioAlcantara-de la Cruz, RicardoTorra, JoelAlcantara, EstebanDe Prado, RafaelFernandes, JoãoHandlehttp://hdl.handle.net/20.500.12207/5424DOIIsPartOfhttps://doi.org/10.1038/s41598-019-51682-z2022-05-05T12:12:40Z2019-01-01T00:00:00Z2019http://purl.org/coar/access_right/c_abf2open accessporEuphorbia heterophyllaporPest controlporExtensive crop areasporImazamoxporControlo de infestantesporHerbicida1632874 byteshttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.ipbeja.pt/bitstreams/44780af2-3b64-4dc7-a3bd-1ecf9cba6984/downloadliteraturehttp://purl.org/coar/resource_type/c_6501journal article
spellingShingle Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
Rojano-Blanco, Antonia
Euphorbia heterophylla
Pest control
Extensive crop areas
Imazamox
Controlo de infestantes
Herbicida
status SINGLETON
subject.fl_str_mv Euphorbia heterophylla
Pest control
Extensive crop areas
Imazamox
Controlo de infestantes
Herbicida
title Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
title_full Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
title_fullStr Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
title_full_unstemmed Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
title_short Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
title_sort Target site as the main mechanism of resistance to imazamox in a Euphorbia heterophylla biotype
topic Euphorbia heterophylla
Pest control
Extensive crop areas
Imazamox
Controlo de infestantes
Herbicida
topic_facet Euphorbia heterophylla
Pest control
Extensive crop areas
Imazamox
Controlo de infestantes
Herbicida
url http://hdl.handle.net/20.500.12207/5424
visible 1