Detalhes bibliográficos
| Resumo: | Abstract: Prescription of potentially inappropriate medication (PIM) in older adults is associated with poor clinical outcomes. The EU (7)-PIM list was created for the European market to improve pharmacotherapy in older adults. Purpose: This work aims to characterize the medication profile and assess the presence of PIM, using the EU (7)-PIM list in older adults' residents at nursing homes. Methods: Retrospective data were collected from the anonymized nursing home records. After PIM identification, a descriptive analysis was performed, and a generalized linear model for dependent negative binomial-type variables was constructed to assess the risk of PIM. Results: Of the 210 participants (mean age 85.10), 82.40% were polymedicated. PIM was observed in 86.4% participants (mean per patient = 2.30± 0.10). The most common PIM were proton pump inhibitors (n = 121, 57.62%), followed by anxiolytics (n = 96, 45.71%). 64.30% of all patients take 2-4 PIM and 5.80% take five or more PIM. The occurrence of PIM is influenced by the number of prescribed medicines (RR 1.14; 95% CI 1.1.-1.17) and the presence of digestive system diseases (RR 1.05; 95% CI 1.0-1.09). Conclusion: The high prevalence of PIM observations highlights the necessity of the implementation of guidelines to prevent PIM. |
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| Autores principais: | Plácido, Ana |
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| Outros Autores: | Aguiar, Ana; Piñeiro-Lamas, María; Varallo, Fabiana; Figueiras, Adolfo; Herdeiro, Maria; Roque, Fátima |
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| Assunto: | elderly institutionalized older adults medication profile prescription |
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| Ano: | 2023 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Instituto Politécnico da Guarda |
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| Idioma: | inglês |
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| Origem: | Repositório Institucional do Instituto Politécnico da Guarda |
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