Publicação
Association between pets and dry eye symptoms: a Chinese national-based study
| Resumo: | Background: Pet-derived allergens are another source of indoor air pollution that could affect human health. However, the association between pet ownership and the risk of dry eye symptoms (DES) remains to be elucidated. Methods: We conducted a nationwide cross-sectional survey among Chinese residents aged over 12 years from June 20, 2022, to August 31, 2022. The Ocular Surface Disease Index-6 (OSDI-6) questionnaire was utilized to evaluate the presence of DES. Multivariable logistic regression models were used to analyze the associations between pet ownership and DES. Subgroup analyses were conducted based on sex, age, residence and affective disorders, and sensitivity analysis by excluding participants with major ocular diseases. The interactions between pet ownership and other risk factors on DES were explored in the additive scale by calculating the synergy index (SI). Results: A total of 21,916 subjects replied to the questionnaire. The prevalence of DES was 43.6 % (95 % confidence interval (CI), 43.0 %-44.3 %). Pet ownership was significantly associated with increased risk of DES (Odds ratio (OR): 1.13, 95%CI: 1.05-1.21), especially among the elderly (OR: 1.28, 95%CI: 1.09-1.51) and urban residents (OR: 1.13, 95%CI: 1.04-1.24). The individual effect of allergic rhinitis on DES was 2.59 (95%CI: 1.27-5.53), while the joint effect of pets and allergic rhinitis was 5.26 (95%CI: 1.20-36.74), suggesting a synergistic interaction with a SI of 2.48 (95%CI: 0.25-24.39). Furthermore, the interaction analysis also indicated a synergistic interaction between pet ownership and low health literacy with a SI of 1.12 (95%CI: 0.66-1.87). Conclusion: Pet ownership was identified as a risk factor for DES. The synergistic interaction of pet ownership and allergic rhinitis suggests shared mechanisms between DES and allergic conditions. |
|---|---|
| Autores principais: | Kai, Jia-Yan |
| Outros Autores: | Wu, Yi-Bo; Chen, Hui-Min; Hu, Dan-Ning; Lança, Carla; Grzybowski, Andrzej; Zhang, Lijun; Zhang, Xiao-Feng; Pan, Chen-Wei |
| Assunto: | Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| Ano: | 2024 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso embargado |
| Instituição associada: | Instituto Politécnico de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório Científico do Instituto Politécnico de Lisboa |
| _version_ | 1866887617014923264 |
|---|---|
| author | Kai, Jia-Yan |
| author2 | Wu, Yi-Bo Chen, Hui-Min Hu, Dan-Ning Lança, Carla Grzybowski, Andrzej Zhang, Lijun Zhang, Xiao-Feng Pan, Chen-Wei |
| author2_role | author author author author author author author author |
| author_facet | Kai, Jia-Yan Wu, Yi-Bo Chen, Hui-Min Hu, Dan-Ning Lança, Carla Grzybowski, Andrzej Zhang, Lijun Zhang, Xiao-Feng Pan, Chen-Wei |
| author_role | author |
| contributor_name_str_mv | RCIPL |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Kai, Jia-Yan\"},{\"Person.name\":\"Wu, Yi-Bo\"},{\"Person.name\":\"Chen, Hui-Min\"},{\"Person.name\":\"Hu, Dan-Ning\"},{\"Person.name\":\"Lança, Carla\",\"Person.identifier.orcid\":\"0000-0001-9918-787X\"},{\"Person.name\":\"Grzybowski, Andrzej\"},{\"Person.name\":\"Zhang, Lijun\"},{\"Person.name\":\"Zhang, Xiao-Feng\"},{\"Person.name\":\"Pan, Chen-Wei\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RCIPL |
| datacite.creators.creator.creatorName.fl_str_mv | Kai, Jia-Yan Wu, Yi-Bo Chen, Hui-Min Hu, Dan-Ning Lança, Carla Grzybowski, Andrzej Zhang, Lijun Zhang, Xiao-Feng Pan, Chen-Wei |
| datacite.date.Accepted.fl_str_mv | 2024-10-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2026-11-13T00:00:00Z |
| datacite.date.embargoed.fl_str_mv | 2026-11-13T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_f1cf |
| datacite.subjects.subject.fl_str_mv | Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| datacite.titles.title.fl_str_mv | Association between pets and dry eye symptoms: a Chinese national-based study |
| dc.contributor.none.fl_str_mv | RCIPL |
| dc.creator.none.fl_str_mv | Kai, Jia-Yan Wu, Yi-Bo Chen, Hui-Min Hu, Dan-Ning Lança, Carla Grzybowski, Andrzej Zhang, Lijun Zhang, Xiao-Feng Pan, Chen-Wei |
| dc.date.Accepted.fl_str_mv | 2024-10-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2026-11-13T00:00:00Z |
| dc.date.embargoed.fl_str_mv | 2026-11-13T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.21/17896 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.cclincense.fl_str_mv | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_f1cf |
| dc.subject.none.fl_str_mv | Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| dc.title.fl_str_mv | Association between pets and dry eye symptoms: a Chinese national-based study |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Background: Pet-derived allergens are another source of indoor air pollution that could affect human health. However, the association between pet ownership and the risk of dry eye symptoms (DES) remains to be elucidated. Methods: We conducted a nationwide cross-sectional survey among Chinese residents aged over 12 years from June 20, 2022, to August 31, 2022. The Ocular Surface Disease Index-6 (OSDI-6) questionnaire was utilized to evaluate the presence of DES. Multivariable logistic regression models were used to analyze the associations between pet ownership and DES. Subgroup analyses were conducted based on sex, age, residence and affective disorders, and sensitivity analysis by excluding participants with major ocular diseases. The interactions between pet ownership and other risk factors on DES were explored in the additive scale by calculating the synergy index (SI). Results: A total of 21,916 subjects replied to the questionnaire. The prevalence of DES was 43.6 % (95 % confidence interval (CI), 43.0 %-44.3 %). Pet ownership was significantly associated with increased risk of DES (Odds ratio (OR): 1.13, 95%CI: 1.05-1.21), especially among the elderly (OR: 1.28, 95%CI: 1.09-1.51) and urban residents (OR: 1.13, 95%CI: 1.04-1.24). The individual effect of allergic rhinitis on DES was 2.59 (95%CI: 1.27-5.53), while the joint effect of pets and allergic rhinitis was 5.26 (95%CI: 1.20-36.74), suggesting a synergistic interaction with a SI of 2.48 (95%CI: 0.25-24.39). Furthermore, the interaction analysis also indicated a synergistic interaction between pet ownership and low health literacy with a SI of 1.12 (95%CI: 0.66-1.87). Conclusion: Pet ownership was identified as a risk factor for DES. The synergistic interaction of pet ownership and allergic rhinitis suggests shared mechanisms between DES and allergic conditions. |
| dirty | 0 |
| eu_rights_str_mv | embargoedAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorio.ipl.pt/bitstreams/1554a75c-c211-49ba-94ad-d8d39c535ac3/download |
| id | ripl_b255f60bb9ba5dec566fc021c072700a |
| identifier.url.fl_str_mv | http://hdl.handle.net/10400.21/17896 |
| instacron_str | ipl |
| institution | Instituto Politécnico de Lisboa |
| instname_str | Instituto Politécnico de Lisboa |
| language | eng |
| network_acronym_str | ripl |
| network_name_str | Repositório Científico do Instituto Politécnico de Lisboa |
| oai_identifier_str | oai:repositorio.ipl.pt:10400.21/17896 |
| organization_str_mv | urn:organizationAcronym:ipl |
| person_str_mv | Kai, Jia-Yan Wu, Yi-Bo Chen, Hui-Min Hu, Dan-Ning Lança, Carla Lança, Carla https://www.ciencia-id.pt/601A-6412-BF2F 601A-6412-BF2F http://orcid.org/0000-0001-9918-787X 0000-0001-9918-787X Grzybowski, Andrzej Zhang, Lijun Zhang, Xiao-Feng Pan, Chen-Wei |
| publishDate | 2024 |
| publisher.none.fl_str_mv | Elsevier |
| reponame_str | Repositório Científico do Instituto Politécnico de Lisboa |
| repository_id_str | urn:repositoryAcronym:ripl |
| service_str_mv | urn:repositoryAcronym:ripl |
| spelling | engElsevierpt_PTBackground: Pet-derived allergens are another source of indoor air pollution that could affect human health. However, the association between pet ownership and the risk of dry eye symptoms (DES) remains to be elucidated. Methods: We conducted a nationwide cross-sectional survey among Chinese residents aged over 12 years from June 20, 2022, to August 31, 2022. The Ocular Surface Disease Index-6 (OSDI-6) questionnaire was utilized to evaluate the presence of DES. Multivariable logistic regression models were used to analyze the associations between pet ownership and DES. Subgroup analyses were conducted based on sex, age, residence and affective disorders, and sensitivity analysis by excluding participants with major ocular diseases. The interactions between pet ownership and other risk factors on DES were explored in the additive scale by calculating the synergy index (SI). Results: A total of 21,916 subjects replied to the questionnaire. The prevalence of DES was 43.6 % (95 % confidence interval (CI), 43.0 %-44.3 %). Pet ownership was significantly associated with increased risk of DES (Odds ratio (OR): 1.13, 95%CI: 1.05-1.21), especially among the elderly (OR: 1.28, 95%CI: 1.09-1.51) and urban residents (OR: 1.13, 95%CI: 1.04-1.24). The individual effect of allergic rhinitis on DES was 2.59 (95%CI: 1.27-5.53), while the joint effect of pets and allergic rhinitis was 5.26 (95%CI: 1.20-36.74), suggesting a synergistic interaction with a SI of 2.48 (95%CI: 0.25-24.39). Furthermore, the interaction analysis also indicated a synergistic interaction between pet ownership and low health literacy with a SI of 1.12 (95%CI: 0.66-1.87). Conclusion: Pet ownership was identified as a risk factor for DES. The synergistic interaction of pet ownership and allergic rhinitis suggests shared mechanisms between DES and allergic conditions.application/pdfpt_PTAssociation between pets and dry eye symptoms: a Chinese national-based studyKai, Jia-YanWu, Yi-BoChen, Hui-MinHu, Dan-NingPersonalLança, CarlaDSpacehttp://dspace.org/items/0320b455-ee19-4670-8bf2-10dce9de1becDSpacehttp://dspace.org/items/0320b455-ee19-4670-8bf2-10dce9de1becLançaCarlaCiência IDhttps://www.ciencia-id.pt601A-6412-BF2FORCIDhttp://orcid.org0000-0001-9918-787XGrzybowski, AndrzejZhang, LijunZhang, Xiao-FengPan, Chen-WeiHostingInstitutionOrganizationalRCIPLe-mailmailto:rcaap@sp.ipl.ptrcaap@sp.ipl.ptDOIIsPartOf10.1016/j.scitotenv.2024.1769542024-102024-10-01T00:00:00Z2026-11-13T00:00:00ZHandlehttp://hdl.handle.net/10400.21/17896http://purl.org/coar/access_right/c_f1cfembargoed accessOphthalmologyAllergic rhinitisDry eyeHealth literacyPets1691290 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2024-10http://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_f1cfapplication/pdffulltexthttps://repositorio.ipl.pt/bitstreams/1554a75c-c211-49ba-94ad-d8d39c535ac3/downloadScience of The Total Environment955176954 |
| spellingShingle | Association between pets and dry eye symptoms: a Chinese national-based study Kai, Jia-Yan Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| status | SINGLETON |
| subject.fl_str_mv | Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| title | Association between pets and dry eye symptoms: a Chinese national-based study |
| title_full | Association between pets and dry eye symptoms: a Chinese national-based study |
| title_fullStr | Association between pets and dry eye symptoms: a Chinese national-based study |
| title_full_unstemmed | Association between pets and dry eye symptoms: a Chinese national-based study |
| title_short | Association between pets and dry eye symptoms: a Chinese national-based study |
| title_sort | Association between pets and dry eye symptoms: a Chinese national-based study |
| topic | Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| topic_facet | Ophthalmology Allergic rhinitis Dry eye Health literacy Pets |
| url | http://hdl.handle.net/10400.21/17896 |
| visible | 1 |