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Comparison study of procedures for aspiration of biopsy samples

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Resumo:Introduction: The samples obtained from fine needle aspiration in liquid base cytology (FNAC) are often limited by scarce cellularity compared to the amount of colloid and presence of blood. Accordingly, it was important to test alternative technical procedures so as to maximize the cellularity of each sample. Objective: To compare the morphological features and cellularity of the three procedures in the FNAC cytodiagnosis of the thyroid. Methods: A total of 31 cases were each subjected to a cell block and ThinPrep preparation as well as a routine smear. The observation and analysis was performed using an optical microscope. Cytological diagnosis of each cell block case was objectively analysed for cellularity, presence of background and cellular preservation. Each smear and ThinPrep case was analysed for the presence or absence of cells. The data was analysed with Microsoft Excel (Office 2010) and SPSS (Statistical Package of Social Science) version 15.0 for Windows. Results: Of 31 cases, only 20 had thyroid cells in the cell block and ThinPrep preparations, however, all smear cases contained thyroid cells. Some background was found in 30 Cell block cases with only 5 of these containing well preserved cells for cytodiagnosis. Conclusions: As indicated by the results, smear is the most appropriate procedure for FNAC of the thyroid.
Autores principais:Mendonça, Paula
Outros Autores:Miúdo, Catarina; Leitão, Dina
Assunto:Fine-needle aspiration Thyroid Cell block Smear ThinPrep
Ano:2014
País:Portugal
Tipo de documento:documento de conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Lisboa
Idioma:inglês
Origem:Repositório Científico do Instituto Politécnico de Lisboa
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author Mendonça, Paula
author2 Miúdo, Catarina
Leitão, Dina
author2_role author
author
author_facet Mendonça, Paula
Miúdo, Catarina
Leitão, Dina
author_role author
contributor_name_str_mv RCIPL
country_str PT
creators_json_txt [{\"Person.name\":\"Mendonça, Paula\"},{\"Person.name\":\"Miúdo, Catarina\"},{\"Person.name\":\"Leitão, Dina\"}]
datacite.contributors.contributor.contributorName.fl_str_mv RCIPL
datacite.creators.creator.creatorName.fl_str_mv Mendonça, Paula
Miúdo, Catarina
Leitão, Dina
datacite.date.Accepted.fl_str_mv 2014-05-01T00:00:00Z
datacite.date.available.fl_str_mv 2016-01-14T16:40:50Z
datacite.date.embargoed.fl_str_mv 2016-01-14T16:40:50Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Fine-needle aspiration
Thyroid
Cell block
Smear
ThinPrep
datacite.titles.title.fl_str_mv Comparison study of procedures for aspiration of biopsy samples
dc.contributor.none.fl_str_mv RCIPL
dc.creator.none.fl_str_mv Mendonça, Paula
Miúdo, Catarina
Leitão, Dina
dc.date.Accepted.fl_str_mv 2014-05-01T00:00:00Z
dc.date.available.fl_str_mv 2016-01-14T16:40:50Z
dc.date.embargoed.fl_str_mv 2016-01-14T16:40:50Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10400.21/5550
dc.language.none.fl_str_mv eng
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Fine-needle aspiration
Thyroid
Cell block
Smear
ThinPrep
dc.title.fl_str_mv Comparison study of procedures for aspiration of biopsy samples
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_c94f
description Introduction: The samples obtained from fine needle aspiration in liquid base cytology (FNAC) are often limited by scarce cellularity compared to the amount of colloid and presence of blood. Accordingly, it was important to test alternative technical procedures so as to maximize the cellularity of each sample. Objective: To compare the morphological features and cellularity of the three procedures in the FNAC cytodiagnosis of the thyroid. Methods: A total of 31 cases were each subjected to a cell block and ThinPrep preparation as well as a routine smear. The observation and analysis was performed using an optical microscope. Cytological diagnosis of each cell block case was objectively analysed for cellularity, presence of background and cellular preservation. Each smear and ThinPrep case was analysed for the presence or absence of cells. The data was analysed with Microsoft Excel (Office 2010) and SPSS (Statistical Package of Social Science) version 15.0 for Windows. Results: Of 31 cases, only 20 had thyroid cells in the cell block and ThinPrep preparations, however, all smear cases contained thyroid cells. Some background was found in 30 Cell block cases with only 5 of these containing well preserved cells for cytodiagnosis. Conclusions: As indicated by the results, smear is the most appropriate procedure for FNAC of the thyroid.
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eu_rights_str_mv openAccess
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fulltext.url.fl_str_mv https://repositorio.ipl.pt/bitstreams/03b96f1e-2827-4552-a151-6669506eca01/download
id ripl_d4884bfcdcd252cebb7ca329bc799eb5
identifier.url.fl_str_mv http://hdl.handle.net/10400.21/5550
instacron_str ipl
institution Instituto Politécnico de Lisboa
instname_str Instituto Politécnico de Lisboa
language eng
network_acronym_str ripl
network_name_str Repositório Científico do Instituto Politécnico de Lisboa
oai_identifier_str oai:repositorio.ipl.pt:10400.21/5550
organization_str_mv urn:organizationAcronym:ipl
person_str_mv Mendonça, Paula
Miúdo, Catarina
Leitão, Dina
publishDate 2014
reponame_str Repositório Científico do Instituto Politécnico de Lisboa
repository_id_str urn:repositoryAcronym:ripl
service_str_mv urn:repositoryAcronym:ripl
spelling engpt_PTIntroduction: The samples obtained from fine needle aspiration in liquid base cytology (FNAC) are often limited by scarce cellularity compared to the amount of colloid and presence of blood. Accordingly, it was important to test alternative technical procedures so as to maximize the cellularity of each sample. Objective: To compare the morphological features and cellularity of the three procedures in the FNAC cytodiagnosis of the thyroid. Methods: A total of 31 cases were each subjected to a cell block and ThinPrep preparation as well as a routine smear. The observation and analysis was performed using an optical microscope. Cytological diagnosis of each cell block case was objectively analysed for cellularity, presence of background and cellular preservation. Each smear and ThinPrep case was analysed for the presence or absence of cells. The data was analysed with Microsoft Excel (Office 2010) and SPSS (Statistical Package of Social Science) version 15.0 for Windows. Results: Of 31 cases, only 20 had thyroid cells in the cell block and ThinPrep preparations, however, all smear cases contained thyroid cells. Some background was found in 30 Cell block cases with only 5 of these containing well preserved cells for cytodiagnosis. Conclusions: As indicated by the results, smear is the most appropriate procedure for FNAC of the thyroid.application/pdfpt_PTComparison study of procedures for aspiration of biopsy samplesMendonça, PaulaMiúdo, CatarinaLeitão, DinaHostingInstitutionOrganizationalRCIPLe-mailmailto:rcaap@sp.ipl.ptrcaap@sp.ipl.pt2016-01-14T16:40:50Z2014-052014-05-01T00:00:00ZHandlehttp://hdl.handle.net/10400.21/5550http://purl.org/coar/access_right/c_abf2open accessFine-needle aspirationThyroidCell blockSmearThinPrep2966084 bytesother research producthttp://purl.org/coar/resource_type/c_c94fconference object2014-05http://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorio.ipl.pt/bitstreams/03b96f1e-2827-4552-a151-6669506eca01/downloadRevista de Saúde Pública48284284
spellingShingle Comparison study of procedures for aspiration of biopsy samples
Mendonça, Paula
Fine-needle aspiration
Thyroid
Cell block
Smear
ThinPrep
status SINGLETON
subject.fl_str_mv Fine-needle aspiration
Thyroid
Cell block
Smear
ThinPrep
title Comparison study of procedures for aspiration of biopsy samples
title_full Comparison study of procedures for aspiration of biopsy samples
title_fullStr Comparison study of procedures for aspiration of biopsy samples
title_full_unstemmed Comparison study of procedures for aspiration of biopsy samples
title_short Comparison study of procedures for aspiration of biopsy samples
title_sort Comparison study of procedures for aspiration of biopsy samples
topic Fine-needle aspiration
Thyroid
Cell block
Smear
ThinPrep
topic_facet Fine-needle aspiration
Thyroid
Cell block
Smear
ThinPrep
url http://hdl.handle.net/10400.21/5550
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