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An Application for Studying Tandem Repeats in Orthologous Genes

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Resumo:Several authors have being suggesting that the occurrence of amino acids repeats in some genes are implied in human diseases. We aim to investigate if these repetitions, which one can observe in humans, also exist in orthologous genes of several organisms, and how they have evolved along time. However, for this kind of study, it is necessary to use different databases and computation methods that are not integrated in any specific tool. In this paper, we present a bioinformatics application, supported by Web Services, that allows to conduct comparative analysis studies for various organisms, along the evolutionary chain.
Autores principais:Lousado, José
Outros Autores:Oliveira, José; Moura, Gabriela; Santos, Manuel
Assunto:Data integration Web Services Tandem repeats Codon repetitions
Ano:2010
País:Portugal
Tipo de documento:capítulo de livro
Tipo de acesso:acesso restrito
Instituição associada:Instituto Politécnico de Viseu
Idioma:inglês
Origem:Repositório Científico do Instituto Politécnico de Viseu

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