Publicação
Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools
| Resumo: | Cold-adapted microorganisms inhabiting permanently low-temperature environments were initially just a biological curiosity but have emerged as rich sources of numerous valuable tools for application in a broad spectrum of innovative technologies. To overcome the multiple challenges inherent to life in their cold habitats, these microorganisms have developed a diverse array of highly sophisticated synergistic adaptations at all levels within their cells: from cell envelope and enzyme adaptation, to cryoprotectant and chaperone production, and novel metabolic capabilities. Basic research has provided valuable insights into how these microorganisms can thrive in their challenging habitat conditions and into the mechanisms of action of the various adaptive features employed, and such insights have served as a foundation for the knowledge-based development of numerous novel biotechnological tools. In this review, we describe the current knowledge of the adaptation strategies of cold-adapted microorganisms and the biotechnological perspectives and commercial tools emerging from this knowledge. Adaptive features and, where possible, applications, in relation to membrane fatty acids, membrane pigments, the cell wall peptidoglycan layer, the lipopolysaccharide component of the outer cell membrane, compatible solutes, antifreeze and ice-nucleating proteins, extracellular polymeric substances, biosurfactants, chaperones, storage materials such as polyhydroxyalkanoates and cyanophycins and metabolic adjustments are presented and discussed. |
|---|---|
| Autores principais: | Collins, Tony |
| Outros Autores: | Margesin, Rosa |
| Assunto: | Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments Ciências Naturais::Ciências Biológicas |
| Ano: | 2019 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1867439248569794560 |
|---|---|
| author | Collins, Tony |
| author2 | Margesin, Rosa |
| author2_role | author |
| author_facet | Collins, Tony Margesin, Rosa |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Collins, Tony\"},{\"Person.name\":\"Margesin, Rosa\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Collins, Tony Margesin, Rosa |
| datacite.date.Accepted.fl_str_mv | 2019-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2021-01-01T07:01:11Z |
| datacite.date.embargoed.fl_str_mv | 2021-01-01T07:01:11Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments Ciências Naturais::Ciências Biológicas |
| datacite.titles.title.fl_str_mv | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Collins, Tony Margesin, Rosa |
| dc.date.Accepted.fl_str_mv | 2019-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2021-01-01T07:01:11Z |
| dc.date.embargoed.fl_str_mv | 2021-01-01T07:01:11Z |
| dc.format.none.fl_str_mv | application/pdf application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/59565 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Springer |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments Ciências Naturais::Ciências Biológicas |
| dc.title.fl_str_mv | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Cold-adapted microorganisms inhabiting permanently low-temperature environments were initially just a biological curiosity but have emerged as rich sources of numerous valuable tools for application in a broad spectrum of innovative technologies. To overcome the multiple challenges inherent to life in their cold habitats, these microorganisms have developed a diverse array of highly sophisticated synergistic adaptations at all levels within their cells: from cell envelope and enzyme adaptation, to cryoprotectant and chaperone production, and novel metabolic capabilities. Basic research has provided valuable insights into how these microorganisms can thrive in their challenging habitat conditions and into the mechanisms of action of the various adaptive features employed, and such insights have served as a foundation for the knowledge-based development of numerous novel biotechnological tools. In this review, we describe the current knowledge of the adaptation strategies of cold-adapted microorganisms and the biotechnological perspectives and commercial tools emerging from this knowledge. Adaptive features and, where possible, applications, in relation to membrane fatty acids, membrane pigments, the cell wall peptidoglycan layer, the lipopolysaccharide component of the outer cell membrane, compatible solutes, antifreeze and ice-nucleating proteins, extracellular polymeric substances, biosurfactants, chaperones, storage materials such as polyhydroxyalkanoates and cyanophycins and metabolic adjustments are presented and discussed. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorium.uminho.pt/bitstreams/6b26b474-1a11-4c58-8db7-a1dcc5fa81fa/download |
| id | rum_044a00fa2e98cc91ea5b41e8d4cb8ac1 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/59565 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/59565 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Collins, Tony Margesin, Rosa |
| publishDate | 2019 |
| publisher.none.fl_str_mv | Springer |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engSpringerporCold-adapted microorganisms inhabiting permanently low-temperature environments were initially just a biological curiosity but have emerged as rich sources of numerous valuable tools for application in a broad spectrum of innovative technologies. To overcome the multiple challenges inherent to life in their cold habitats, these microorganisms have developed a diverse array of highly sophisticated synergistic adaptations at all levels within their cells: from cell envelope and enzyme adaptation, to cryoprotectant and chaperone production, and novel metabolic capabilities. Basic research has provided valuable insights into how these microorganisms can thrive in their challenging habitat conditions and into the mechanisms of action of the various adaptive features employed, and such insights have served as a foundation for the knowledge-based development of numerous novel biotechnological tools. In this review, we describe the current knowledge of the adaptation strategies of cold-adapted microorganisms and the biotechnological perspectives and commercial tools emerging from this knowledge. Adaptive features and, where possible, applications, in relation to membrane fatty acids, membrane pigments, the cell wall peptidoglycan layer, the lipopolysaccharide component of the outer cell membrane, compatible solutes, antifreeze and ice-nucleating proteins, extracellular polymeric substances, biosurfactants, chaperones, storage materials such as polyhydroxyalkanoates and cyanophycins and metabolic adjustments are presented and discussed.application/pdfapplication/pdfengPsychrophilic lifestyles: mechanisms of adaptation and biotechnological toolsCollins, TonyMargesin, RosaHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptCITATIONCollins T. and Margesin R. (2019). Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools. Applied Microbiology and Biotechnology. pp. 1-15. DOI: 10.1007/s00253-019-09659-5PMID30729286ISSNIsPartOf0175-7598DOIIsPartOf10.1007/s00253-019-09659-52021-01-01T07:01:11Z20192019-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/59565http://purl.org/coar/access_right/c_abf2open accessPsychrophilesCold adaptationCell envelopeCryoprotectionEnzymesChaperonesMetabolic adjustmentshttp://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Ciências Naturais::Ciências Biológicas710326 bytes667005 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/6b26b474-1a11-4c58-8db7-a1dcc5fa81fa/downloadhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/09e1359b-e55f-4165-b354-c229b613cef1/download |
| spellingShingle | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools Collins, Tony Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments Ciências Naturais::Ciências Biológicas |
| status | SINGLETON |
| subject.fl_str_mv | Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments |
| subject.other.fl_str_mv | Ciências Naturais::Ciências Biológicas |
| title | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| title_full | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| title_fullStr | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| title_full_unstemmed | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| title_short | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| title_sort | Psychrophilic lifestyles: mechanisms of adaptation and biotechnological tools |
| topic | Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments Ciências Naturais::Ciências Biológicas |
| topic_facet | Psychrophiles Cold adaptation Cell envelope Cryoprotection Enzymes Chaperones Metabolic adjustments Ciências Naturais::Ciências Biológicas |
| url | https://hdl.handle.net/1822/59565 |
| visible | 1 |