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Potencialities of electrospun mats based on PVA/CA for applications as chronic wound dressings

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Resumo:Chronic wounds are unable to follow the normal healing steps, taking more than 12 weeks to heal They are characterized by a defective matrix and cell debris impair healing, prolonged inflammation, moisture imbalance and high bacteria amounts Bacterial infections are the main cause behind complications with the healing of chronic wounds. Biodegradable polymeric wound dressings were engineered by electrospinning with a porous fibrous nanostruture resembling the extracellular matrix The goal was to generate dressings with thin fiber diameters that, in the future, will be functionalized with antimicrobial peptides ( with immunoregulatory properties, to prevent bacterial colonization and fight infection.
Autores principais:Teixeira, Marta Albertina
Outros Autores:Amorim, M. T. Pessoa de; Felgueiras, Helena Prado
Assunto:Poly(vinyl alcohol) Cellulose acetate Electrospun nanofibers Wound healing
Ano:2019
País:Portugal
Tipo de documento:póster em conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho

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