Publicação

Diastereo-selectivity in diels–alder cycloadditions of erythrose benzylidene-acetal 1,3-Butadienes with maleimides

Detalhes bibliográficos
Resumo:	Maleimides were combined with D-erythrose benzylidene-acetal 1,3-butadienes 1 and 2 to study the facial selectivity of the Diels-Alder cycloadditions. The selectivity was found to be from moderate to good. The reaction diastereotopicity can be reversed with the temperature. Simultaneous coordination of diene 1, having a free hydroxyl group, and maleimide 3 to a chiral bimetallic Lewis acid catalyst (LACASA-DA reaction) occurs with complete diastereo-control to give a single adduct, using an extra chiral inductor either R- or S-BINOL.
Autores principais:	Salgueiro, D. A. L.
Outros Autores:	Duarte, Vera C. M.; Sousa, Cristina; Alves, M. José; Fortes, A. Gil
Assunto:	maleimides D-erythrose benzylidene-acetal 1,3-butadiene Diels-Alder cycloaddition selectivity
Ano:	2012
País:	Portugal
Tipo de documento:	artigo
Tipo de acesso:	acesso aberto
Instituição associada:	Universidade do Minho
Idioma:	inglês
Origem:	RepositóriUM - Universidade do Minho

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