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Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model

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Resumo:In this study, the capacity of Saccharomyces cerevisiae to adsorb fumonisin B-1 (FB1) was evaluated in in vitro assays. The digestion of nutrients from maize contaminated with FB1 was assessed as well as the influence of digestive enzymes and pH on the bioavailability of FB1 in solution. Adsorption assays in buffers containing 5 mu g/ml of FB1 were conducted to determine the strain to be used in the in vitro digestion assays. Four different yeast strains (1, 2, 3 and 4) along with five different cell concentrations of each one were studied under pH 2 and 6.8 at 39 degrees C. Strain 4 showed higher adsorption values at 1x10(9) cfu/ml, adsorbing 39.4% of the mycotoxin at pH 2 and 37.5% at pH 6.8. After that, the in vitro enzymatic digestion was conducted in two separated experiments. First, maize artificially contaminated with FB1 (5 mu g/g) was used in five different treatments. Then, assays with maize naturally contaminated with FB1 (Maize A: 3.2 mu g/g and Maize B: 29.0 mu g/g) were conducted. In all samples, FB1 was quantified by HPLC-FL in liquid fraction and in solid residue. Samples of maize in natura and solid residues were subjected to chemical analysis of dry matter, organic matter, crude protein, neutral detergent fibre and starch to estimate the digestion of nutrients. The presences of FB1 and S. cerevisiae (Strain 4) in these assays had no influence on the digestion of the maize nutrients. The adsorption capacity of yeast was observed more clearly in treatments with higher concentrations of FB1 in the maize grain. S. cerevisiae strain 4 removed between 8 to 18% of FB1 in solution, showing a limited capacity to adsorb FB1 under in vitro conditions of horse enzymatic digestion.
Autores principais:Taran, F. M. P.
Outros Autores:Silva, V. P.; Abrunhosa, Luís; Rosa, C. A. R.; Venâncio, Armando; Almeida, F. Q.
Assunto:Adsorption Equine In vitro digestion Leukoencephalomalacia Yeast
Ano:2017
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Taran, F. M. P.
author2 Silva, V. P.
Abrunhosa, Luís
Rosa, C. A. R.
Venâncio, Armando
Almeida, F. Q.
author2_role author
author
author
author
author
author_facet Taran, F. M. P.
Silva, V. P.
Abrunhosa, Luís
Rosa, C. A. R.
Venâncio, Armando
Almeida, F. Q.
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Taran, F. M. P.\"},{\"Person.name\":\"Silva, V. P.\"},{\"Person.name\":\"Abrunhosa, Luís\"},{\"Person.name\":\"Rosa, C. A. R.\"},{\"Person.name\":\"Venâncio, Armando\"},{\"Person.name\":\"Almeida, F. Q.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Taran, F. M. P.
Silva, V. P.
Abrunhosa, Luís
Rosa, C. A. R.
Venâncio, Armando
Almeida, F. Q.
datacite.date.Accepted.fl_str_mv 2017-01-01T00:00:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Adsorption
Equine
In vitro digestion
Leukoencephalomalacia
Yeast
datacite.titles.title.fl_str_mv Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Taran, F. M. P.
Silva, V. P.
Abrunhosa, Luís
Rosa, C. A. R.
Venâncio, Armando
Almeida, F. Q.
dc.date.Accepted.fl_str_mv 2017-01-01T00:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/46875
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Wageningen Academic Publishers
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Adsorption
Equine
In vitro digestion
Leukoencephalomalacia
Yeast
dc.title.fl_str_mv Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description In this study, the capacity of Saccharomyces cerevisiae to adsorb fumonisin B-1 (FB1) was evaluated in in vitro assays. The digestion of nutrients from maize contaminated with FB1 was assessed as well as the influence of digestive enzymes and pH on the bioavailability of FB1 in solution. Adsorption assays in buffers containing 5 mu g/ml of FB1 were conducted to determine the strain to be used in the in vitro digestion assays. Four different yeast strains (1, 2, 3 and 4) along with five different cell concentrations of each one were studied under pH 2 and 6.8 at 39 degrees C. Strain 4 showed higher adsorption values at 1x10(9) cfu/ml, adsorbing 39.4% of the mycotoxin at pH 2 and 37.5% at pH 6.8. After that, the in vitro enzymatic digestion was conducted in two separated experiments. First, maize artificially contaminated with FB1 (5 mu g/g) was used in five different treatments. Then, assays with maize naturally contaminated with FB1 (Maize A: 3.2 mu g/g and Maize B: 29.0 mu g/g) were conducted. In all samples, FB1 was quantified by HPLC-FL in liquid fraction and in solid residue. Samples of maize in natura and solid residues were subjected to chemical analysis of dry matter, organic matter, crude protein, neutral detergent fibre and starch to estimate the digestion of nutrients. The presences of FB1 and S. cerevisiae (Strain 4) in these assays had no influence on the digestion of the maize nutrients. The adsorption capacity of yeast was observed more clearly in treatments with higher concentrations of FB1 in the maize grain. S. cerevisiae strain 4 removed between 8 to 18% of FB1 in solution, showing a limited capacity to adsorb FB1 under in vitro conditions of horse enzymatic digestion.
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identifier.url.fl_str_mv https://hdl.handle.net/1822/46875
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instname_str Universidade do Minho
language eng
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organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Taran, F. M. P.
Silva, V. P.
Abrunhosa, Luís
Rosa, C. A. R.
Venâncio, Armando
Almeida, F. Q.
publishDate 2017
publisher.none.fl_str_mv Wageningen Academic Publishers
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
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spelling engWageningen Academic PublishersporIn this study, the capacity of Saccharomyces cerevisiae to adsorb fumonisin B-1 (FB1) was evaluated in in vitro assays. The digestion of nutrients from maize contaminated with FB1 was assessed as well as the influence of digestive enzymes and pH on the bioavailability of FB1 in solution. Adsorption assays in buffers containing 5 mu g/ml of FB1 were conducted to determine the strain to be used in the in vitro digestion assays. Four different yeast strains (1, 2, 3 and 4) along with five different cell concentrations of each one were studied under pH 2 and 6.8 at 39 degrees C. Strain 4 showed higher adsorption values at 1x10(9) cfu/ml, adsorbing 39.4% of the mycotoxin at pH 2 and 37.5% at pH 6.8. After that, the in vitro enzymatic digestion was conducted in two separated experiments. First, maize artificially contaminated with FB1 (5 mu g/g) was used in five different treatments. Then, assays with maize naturally contaminated with FB1 (Maize A: 3.2 mu g/g and Maize B: 29.0 mu g/g) were conducted. In all samples, FB1 was quantified by HPLC-FL in liquid fraction and in solid residue. Samples of maize in natura and solid residues were subjected to chemical analysis of dry matter, organic matter, crude protein, neutral detergent fibre and starch to estimate the digestion of nutrients. The presences of FB1 and S. cerevisiae (Strain 4) in these assays had no influence on the digestion of the maize nutrients. The adsorption capacity of yeast was observed more clearly in treatments with higher concentrations of FB1 in the maize grain. S. cerevisiae strain 4 removed between 8 to 18% of FB1 in solution, showing a limited capacity to adsorb FB1 under in vitro conditions of horse enzymatic digestion.application/pdfporEvaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion modelTaran, F. M. P.Silva, V. P.Abrunhosa, LuísRosa, C. A. R.Venâncio, ArmandoAlmeida, F. Q.HostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1875-0710DOIIsPartOf10.3920/WMJ2016.204420172017-10-27T08:54:22Z2017-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/46875http://purl.org/coar/access_right/c_16ecrestricted accessAdsorptionEquineIn vitro digestionLeukoencephalomalaciaYeast376593 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/0bc95f99-2b71-43d9-9579-a81c17ce3670/download
spellingShingle Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
Taran, F. M. P.
Adsorption
Equine
In vitro digestion
Leukoencephalomalacia
Yeast
status SINGLETON
subject.fl_str_mv Adsorption
Equine
In vitro digestion
Leukoencephalomalacia
Yeast
title Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
title_full Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
title_fullStr Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
title_full_unstemmed Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
title_short Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
title_sort Evaluation of Saccharomyces cerevisiae as an anti-fumonisin B-1 additive in a horse digestion model
topic Adsorption
Equine
In vitro digestion
Leukoencephalomalacia
Yeast
topic_facet Adsorption
Equine
In vitro digestion
Leukoencephalomalacia
Yeast
url https://hdl.handle.net/1822/46875
visible 1