Publicação
In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video)
| Resumo: | Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Background: Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Objective: To evaluate the reliability of the OTSC system in vivo after transgastric testicular vessel ligation (varicocelectomy model). Design: There were 3 experimental groups (5 animals in each): groups 1 and 3, gastrotomy dilation up to 18 mm, surgery was performed with a double-channel endoscope; group 2, gastrotomy dilation up to 13 mm, surgery was performed with a single-channel endoscope. Setting: Surgical Sciences Research Domain, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. Interventions: Bilateral testicular vessel ligation by transgastric access. Gastrotomy closed with the largest version of OTSC system (12 mm): a single clip in groups 1 and 2, and 2 clips in group 3. Animals were monitored for 2 weeks, killed, and submitted for necropsy. Main Outcome Measurements: Adequacy of closure and healing after the use of the OTSC system. Statistical analysis. Results: Vessel ligation was easily achieved in all groups. Although differences in the complication rate did not reach statistical significance (P Z .099), there was a clear tendency for a better prognosis in groups 2 and 3 than group 1. In fact, only 2 animals from group 1 had complications related to incomplete gastrotomy closure. Limitations: Small number of animals per group; nonrandomized study. Conclusions: The OTSC system was shown to be easy and efficient for gastrotomy closure in a survival experimental model of varicocelectomy, when correctly matching the gastrotomy size with the clip size and/or number |
|---|---|
| Autores principais: | Rolanda, Carla |
| Outros Autores: | Lima, Estêvão Augusto Rodrigues de; Silva, David; Moreira, Ivone; Pêgo, José M.; Macedo, Guilherme; Correia-Pinto, Jorge |
| Assunto: | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| Ano: | 2009 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1866876039744978944 |
|---|---|
| author | Rolanda, Carla |
| author2 | Lima, Estêvão Augusto Rodrigues de Silva, David Moreira, Ivone Pêgo, José M. Macedo, Guilherme Correia-Pinto, Jorge |
| author2_role | author author author author author author |
| author_facet | Rolanda, Carla Lima, Estêvão Augusto Rodrigues de Silva, David Moreira, Ivone Pêgo, José M. Macedo, Guilherme Correia-Pinto, Jorge |
| author_role | author |
| contributor_name_str_mv | Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Rolanda, Carla\"},{\"Person.name\":\"Lima, Estêvão Augusto Rodrigues de\"},{\"Person.name\":\"Silva, David\"},{\"Person.name\":\"Moreira, Ivone\"},{\"Person.name\":\"Pêgo, José M.\"},{\"Person.name\":\"Macedo, Guilherme\"},{\"Person.name\":\"Correia-Pinto, Jorge\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Rolanda, Carla Lima, Estêvão Augusto Rodrigues de Silva, David Moreira, Ivone Pêgo, José M. Macedo, Guilherme Correia-Pinto, Jorge |
| datacite.date.Accepted.fl_str_mv | 2009-12-01T00:00:00Z |
| datacite.date.embargoed.fl_str_mv | 10000-01-01T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| datacite.subjects.subject.fl_str_mv | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| datacite.titles.title.fl_str_mv | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| dc.contributor.none.fl_str_mv | Universidade do Minho |
| dc.creator.none.fl_str_mv | Rolanda, Carla Lima, Estêvão Augusto Rodrigues de Silva, David Moreira, Ivone Pêgo, José M. Macedo, Guilherme Correia-Pinto, Jorge |
| dc.date.Accepted.fl_str_mv | 2009-12-01T00:00:00Z |
| dc.date.embargoed.fl_str_mv | 10000-01-01T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/67634 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Elsevier |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_16ec |
| dc.subject.none.fl_str_mv | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| dc.title.fl_str_mv | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Background: Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Objective: To evaluate the reliability of the OTSC system in vivo after transgastric testicular vessel ligation (varicocelectomy model). Design: There were 3 experimental groups (5 animals in each): groups 1 and 3, gastrotomy dilation up to 18 mm, surgery was performed with a double-channel endoscope; group 2, gastrotomy dilation up to 13 mm, surgery was performed with a single-channel endoscope. Setting: Surgical Sciences Research Domain, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. Interventions: Bilateral testicular vessel ligation by transgastric access. Gastrotomy closed with the largest version of OTSC system (12 mm): a single clip in groups 1 and 2, and 2 clips in group 3. Animals were monitored for 2 weeks, killed, and submitted for necropsy. Main Outcome Measurements: Adequacy of closure and healing after the use of the OTSC system. Statistical analysis. Results: Vessel ligation was easily achieved in all groups. Although differences in the complication rate did not reach statistical significance (P Z .099), there was a clear tendency for a better prognosis in groups 2 and 3 than group 1. In fact, only 2 animals from group 1 had complications related to incomplete gastrotomy closure. Limitations: Small number of animals per group; nonrandomized study. Conclusions: The OTSC system was shown to be easy and efficient for gastrotomy closure in a survival experimental model of varicocelectomy, when correctly matching the gastrotomy size with the clip size and/or number |
| dirty | 0 |
| eu_rights_str_mv | restrictedAccess |
| format | article |
| fulltext.url.fl_str_mv | https://prod-dspace.uminho.pt/bitstreams/49a413f7-5075-4220-b871-7eb8eba662d5/download |
| id | rum_3dee38ffe95f128b05c62a28f0bc2dfd |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/67634 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/67634 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Rolanda, Carla Lima, Estêvão Augusto Rodrigues de Silva, David Moreira, Ivone Pêgo, José M. Macedo, Guilherme Correia-Pinto, Jorge |
| publishDate | 2009 |
| publisher.none.fl_str_mv | Elsevier |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engElsevierporGastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Background: Gastrotomy closure remains the major limiting factor for human translation of transgastric surgery; the over-the-scope clip (OTSC) system was proposed as a possibility for this purpose. Transgastric access is good for a pelvic approach, making varicocelectomy a possible indication for natural orifice transluminal endoscopic surgery (NOTES). Objective: To evaluate the reliability of the OTSC system in vivo after transgastric testicular vessel ligation (varicocelectomy model). Design: There were 3 experimental groups (5 animals in each): groups 1 and 3, gastrotomy dilation up to 18 mm, surgery was performed with a double-channel endoscope; group 2, gastrotomy dilation up to 13 mm, surgery was performed with a single-channel endoscope. Setting: Surgical Sciences Research Domain, Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. Interventions: Bilateral testicular vessel ligation by transgastric access. Gastrotomy closed with the largest version of OTSC system (12 mm): a single clip in groups 1 and 2, and 2 clips in group 3. Animals were monitored for 2 weeks, killed, and submitted for necropsy. Main Outcome Measurements: Adequacy of closure and healing after the use of the OTSC system. Statistical analysis. Results: Vessel ligation was easily achieved in all groups. Although differences in the complication rate did not reach statistical significance (P Z .099), there was a clear tendency for a better prognosis in groups 2 and 3 than group 1. In fact, only 2 animals from group 1 had complications related to incomplete gastrotomy closure. Limitations: Small number of animals per group; nonrandomized study. Conclusions: The OTSC system was shown to be easy and efficient for gastrotomy closure in a survival experimental model of varicocelectomy, when correctly matching the gastrotomy size with the clip size and/or numberapplication/pdfporIn vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video)Rolanda, CarlaLima, Estêvão Augusto Rodrigues deSilva, DavidMoreira, IvonePêgo, José M.Macedo, GuilhermeCorreia-Pinto, JorgeHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf0016-5107DOIIsPartOf10.1016/j.gie.2009.04.0542009-122009-12-01T00:00:00Z10000-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/67634http://purl.org/coar/access_right/c_16ecrestricted accessAnimalsGastroscopyLigationMaleStomachSwineTestisUrologic Surgical Procedures, MaleVaricoceleVideo RecordingSurgical Instruments1504902 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_f1cfapplication/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/49a413f7-5075-4220-b871-7eb8eba662d5/download |
| spellingShingle | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) Rolanda, Carla Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| status | SINGLETON |
| subject.fl_str_mv | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| title | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| title_full | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| title_fullStr | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| title_full_unstemmed | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| title_short | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| title_sort | In vivo assessment of gastrotomy closure with over-the-scope clips in an experimental model for varicocelectomy (with video) |
| topic | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| topic_facet | Animals Gastroscopy Ligation Male Stomach Swine Testis Urologic Surgical Procedures, Male Varicocele Video Recording Surgical Instruments |
| url | https://hdl.handle.net/1822/67634 |
| visible | 1 |