Publicação
Unnatural benz-X-azolyl asparagine derivatives as novel fluorescent amino acids : synthesis and photophysical characterization
| Resumo: | A family of new asparagine derivatives bearing benzothiazole and benzimidazole units, functionalised with electron donor or acceptor groups, were synthesized in good to excellent yields. The photophysical characterization of these new heterocyclic amino acids was performed by UV-visible absorption and fluorescence emission studies and revealed that the compounds displayed remarkably high fluorescence quantum yields and Stokes’ shifts, making them good candidates for application as fluorescent probes by incorporation into peptidic frameworks. |
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| Autores principais: | Esteves, Cátia I. C. |
| Outros Autores: | Silva, Ana M. F.; Raposo, M. Manuela M.; Costa, Susana P. G. |
| Assunto: | Asparagine Unnatural amino acids Benzothiazole Fluorescent probes Solvatochromism Benzimidazole |
| Ano: | 2009 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| Resumo: | A family of new asparagine derivatives bearing benzothiazole and benzimidazole units, functionalised with electron donor or acceptor groups, were synthesized in good to excellent yields. The photophysical characterization of these new heterocyclic amino acids was performed by UV-visible absorption and fluorescence emission studies and revealed that the compounds displayed remarkably high fluorescence quantum yields and Stokes’ shifts, making them good candidates for application as fluorescent probes by incorporation into peptidic frameworks. |
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