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Osteochondral tissue engineering: challenges, current strategies, and technological advances

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Resumo:In the last few years, osteochondral tissue engineering has shown an increasing development in advanced tools and technologies for damaged underlying subchondral bone and cartilage tissue repair and regeneration. Considering the limitation of articular cartilage to heal and self-repair, new therapeutic options are essential to develop approaches based on suitable strategies made of appropriate engineered biomaterials. This book overviews the most recent developments in the field of osteochondral tissue engineering. It covers the concepts and current challenges for bone and cartilage repair and regeneration, along with technological advances for osteochondral tissue. Specific topics include viscosupplementation, tissue engineering approaches, technological advances with stem cells and cell-based therapies with applications for osteochondral, bioreactors and microfluidics including multi-chamber bioreactors, and in vitro and in vivo mimetic models. This book presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish the osteochondral interface formation in order to translate it into a clinical setting. Each chapter is prepared by world know expert on their field, and serves as a core reference for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.
Autores principais:Oliveira, Joaquim M.
Outros Autores:Pina, Sandra Cristina Almeida; San Roman, Julio; Reis, R. L.
Assunto:Osteochondral Tissue engineering
Ano:2018
País:Portugal
Tipo de documento:livro
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Oliveira, Joaquim M.
author2 Pina, Sandra Cristina Almeida
San Roman, Julio
Reis, R. L.
author2_role author
author
author
author_facet Oliveira, Joaquim M.
Pina, Sandra Cristina Almeida
San Roman, Julio
Reis, R. L.
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Oliveira, Joaquim M.\"},{\"Person.name\":\"Pina, Sandra Cristina Almeida\"},{\"Person.name\":\"San Roman, Julio\"},{\"Person.name\":\"Reis, R. L.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Oliveira, Joaquim M.
Pina, Sandra Cristina Almeida
San Roman, Julio
Reis, R. L.
datacite.date.Accepted.fl_str_mv 2018-01-01T00:00:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Osteochondral
Tissue engineering
datacite.titles.title.fl_str_mv Osteochondral tissue engineering: challenges, current strategies, and technological advances
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Oliveira, Joaquim M.
Pina, Sandra Cristina Almeida
San Roman, Julio
Reis, R. L.
dc.date.Accepted.fl_str_mv 2018-01-01T00:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/58803
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Springer
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Osteochondral
Tissue engineering
dc.title.fl_str_mv Osteochondral tissue engineering: challenges, current strategies, and technological advances
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_2f33
description In the last few years, osteochondral tissue engineering has shown an increasing development in advanced tools and technologies for damaged underlying subchondral bone and cartilage tissue repair and regeneration. Considering the limitation of articular cartilage to heal and self-repair, new therapeutic options are essential to develop approaches based on suitable strategies made of appropriate engineered biomaterials. This book overviews the most recent developments in the field of osteochondral tissue engineering. It covers the concepts and current challenges for bone and cartilage repair and regeneration, along with technological advances for osteochondral tissue. Specific topics include viscosupplementation, tissue engineering approaches, technological advances with stem cells and cell-based therapies with applications for osteochondral, bioreactors and microfluidics including multi-chamber bioreactors, and in vitro and in vivo mimetic models. This book presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish the osteochondral interface formation in order to translate it into a clinical setting. Each chapter is prepared by world know expert on their field, and serves as a core reference for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.
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id rum_50c622c94dea72f2a54d210236d0df78
identifier.url.fl_str_mv https://hdl.handle.net/1822/58803
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
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organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Oliveira, Joaquim M.
Pina, Sandra Cristina Almeida
San Roman, Julio
Reis, R. L.
publishDate 2018
publisher.none.fl_str_mv Springer
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engSpringerporIn the last few years, osteochondral tissue engineering has shown an increasing development in advanced tools and technologies for damaged underlying subchondral bone and cartilage tissue repair and regeneration. Considering the limitation of articular cartilage to heal and self-repair, new therapeutic options are essential to develop approaches based on suitable strategies made of appropriate engineered biomaterials. This book overviews the most recent developments in the field of osteochondral tissue engineering. It covers the concepts and current challenges for bone and cartilage repair and regeneration, along with technological advances for osteochondral tissue. Specific topics include viscosupplementation, tissue engineering approaches, technological advances with stem cells and cell-based therapies with applications for osteochondral, bioreactors and microfluidics including multi-chamber bioreactors, and in vitro and in vivo mimetic models. This book presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish the osteochondral interface formation in order to translate it into a clinical setting. Each chapter is prepared by world know expert on their field, and serves as a core reference for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.application/pdfporOsteochondral tissue engineering: challenges, current strategies, and technological advancesOliveira, Joaquim M.Pina, Sandra Cristina AlmeidaSan Roman, JulioReis, R. L.HostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISBNIsPartOf978-3-319-76734-5DOIIsPartOf10.1007/978-3-319-76735-220182018-012019-01-30T10:26:01Z2018-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/58803http://purl.org/coar/access_right/c_16ecrestricted accessOsteochondralTissue engineering13710401 bytesliteraturehttp://purl.org/coar/resource_type/c_2f33bookhttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/477d5fd6-9c49-42b1-9d3c-65e98087d155/download
spellingShingle Osteochondral tissue engineering: challenges, current strategies, and technological advances
Oliveira, Joaquim M.
Osteochondral
Tissue engineering
status SINGLETON
subject.fl_str_mv Osteochondral
Tissue engineering
title Osteochondral tissue engineering: challenges, current strategies, and technological advances
title_full Osteochondral tissue engineering: challenges, current strategies, and technological advances
title_fullStr Osteochondral tissue engineering: challenges, current strategies, and technological advances
title_full_unstemmed Osteochondral tissue engineering: challenges, current strategies, and technological advances
title_short Osteochondral tissue engineering: challenges, current strategies, and technological advances
title_sort Osteochondral tissue engineering: challenges, current strategies, and technological advances
topic Osteochondral
Tissue engineering
topic_facet Osteochondral
Tissue engineering
url https://hdl.handle.net/1822/58803
visible 1