Publicação
Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing
| Resumo: | Modern wound dressings combine medical textiles with active compounds that stimulate wound healing while protecting against infection. Electrospun wound dressings have been extensively studied and the electrospinning technique recognized as an efficient approach for the production of nanoscale fibrous mats. The unique diverse function and architecture of antimicrobial peptides (AMPs) has attracted considerable attention as a tool for the design of new anti-infective drugs. Functionalizing electrospun wound dressings with these AMPs is nowadays being researched. In the present work, we explore these new systems by highlighting the most important characteristics of electropsun wound dressings, revealing the importance of AMPs to wound healing, and the methods available to functionalize the electrospun mats with these molecules. The combined therapeutic potential of collagen type I and these AMP functionalized dressings will be highlighted as well; the significance of these new strategies for the future of wound healing will be clarified. |
|---|---|
| Autores principais: | Felgueiras, Helena Prado |
| Outros Autores: | Amorim, M. T. Pessoa de |
| Assunto: | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I Engenharia e Tecnologia::Engenharia Médica |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | comunicação em conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1867438628833067008 |
|---|---|
| author | Felgueiras, Helena Prado |
| author2 | Amorim, M. T. Pessoa de |
| author2_role | author |
| author_facet | Felgueiras, Helena Prado Amorim, M. T. Pessoa de |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Felgueiras, Helena Prado\"},{\"Person.name\":\"Amorim, M. T. Pessoa de\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Felgueiras, Helena Prado Amorim, M. T. Pessoa de |
| datacite.date.Accepted.fl_str_mv | 2017-11-14T00:00:00Z |
| datacite.date.available.fl_str_mv | 2017-11-22T13:58:57Z |
| datacite.date.embargoed.fl_str_mv | 2017-11-22T13:58:57Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I Engenharia e Tecnologia::Engenharia Médica |
| datacite.titles.title.fl_str_mv | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Felgueiras, Helena Prado Amorim, M. T. Pessoa de |
| dc.date.Accepted.fl_str_mv | 2017-11-14T00:00:00Z |
| dc.date.available.fl_str_mv | 2017-11-22T13:58:57Z |
| dc.date.embargoed.fl_str_mv | 2017-11-22T13:58:57Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/47647 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Institute of Physics Publishing |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I Engenharia e Tecnologia::Engenharia Médica |
| dc.title.fl_str_mv | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_5794 |
| description | Modern wound dressings combine medical textiles with active compounds that stimulate wound healing while protecting against infection. Electrospun wound dressings have been extensively studied and the electrospinning technique recognized as an efficient approach for the production of nanoscale fibrous mats. The unique diverse function and architecture of antimicrobial peptides (AMPs) has attracted considerable attention as a tool for the design of new anti-infective drugs. Functionalizing electrospun wound dressings with these AMPs is nowadays being researched. In the present work, we explore these new systems by highlighting the most important characteristics of electropsun wound dressings, revealing the importance of AMPs to wound healing, and the methods available to functionalize the electrospun mats with these molecules. The combined therapeutic potential of collagen type I and these AMP functionalized dressings will be highlighted as well; the significance of these new strategies for the future of wound healing will be clarified. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | conferencePaper |
| fulltext.url.fl_str_mv | https://repositorium.uminho.pt/bitstreams/5e30bdb7-8e04-415b-b1b1-315cbf11e0ec/download |
| id | rum_51148efe1de73e4c60f1d48cc8a79e3f |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/47647 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/47647 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Felgueiras, Helena Prado Amorim, M. T. Pessoa de |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Institute of Physics Publishing |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engInstitute of Physics PublishingporModern wound dressings combine medical textiles with active compounds that stimulate wound healing while protecting against infection. Electrospun wound dressings have been extensively studied and the electrospinning technique recognized as an efficient approach for the production of nanoscale fibrous mats. The unique diverse function and architecture of antimicrobial peptides (AMPs) has attracted considerable attention as a tool for the design of new anti-infective drugs. Functionalizing electrospun wound dressings with these AMPs is nowadays being researched. In the present work, we explore these new systems by highlighting the most important characteristics of electropsun wound dressings, revealing the importance of AMPs to wound healing, and the methods available to functionalize the electrospun mats with these molecules. The combined therapeutic potential of collagen type I and these AMP functionalized dressings will be highlighted as well; the significance of these new strategies for the future of wound healing will be clarified.application/pdfporElectrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healingFelgueiras, Helena PradoAmorim, M. T. Pessoa deHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1757-8981DOIIsPartOf10.1088/1757-899X/254/6/0620042017-11-22T13:58:57Z2017-11-142017-11-14T00:00:00ZHandlehttps://hdl.handle.net/1822/47647http://purl.org/coar/access_right/c_abf2open accessElectrospun wound dressingsFunctionalizationAntimicrobial peptidesCollagen type Ihttp://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Engenharia e Tecnologia::Engenharia Médica367645 bytesother research producthttp://purl.org/coar/resource_type/c_5794conference paperhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/5e30bdb7-8e04-415b-b1b1-315cbf11e0ec/download |
| spellingShingle | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing Felgueiras, Helena Prado Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I Engenharia e Tecnologia::Engenharia Médica |
| status | SINGLETON |
| subject.fl_str_mv | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I |
| subject.other.fl_str_mv | Engenharia e Tecnologia::Engenharia Médica |
| title | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| title_full | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| title_fullStr | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| title_full_unstemmed | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| title_short | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| title_sort | Electrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing |
| topic | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I Engenharia e Tecnologia::Engenharia Médica |
| topic_facet | Electrospun wound dressings Functionalization Antimicrobial peptides Collagen type I Engenharia e Tecnologia::Engenharia Médica |
| url | https://hdl.handle.net/1822/47647 |
| visible | 1 |