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New valorization strategies for eucalyptus spp. bark extracts

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Resumo:The forest-based industry is important industrial sector in Europe, and particularly in Portugal. The increasingly higher demands for competitiveness, in forest-industry prompted the exploitation of different side-streams, such as bark residues. Within a biorefinery-based concept, these residues can be further refined to high value-added chemicals, with relevance for chemical and pharmaceutical industries. Results from our research team reveal that Eucalyptus globulus bark lipophilic extracts contain high quantities of triterpenoids (up to 12 g kg −1 bark), predominantly triterpenic acids (TAs), namely betulinic, betulonic, ursolic and oleanolic acids. Similar compo- sition has also been detected on Eucalyptus nitens outer bark. In the present work we report the chemical characterization of Eucalyptus spp. bark derived extracts, rich in TAs and the assessment of their antitumoral potential, using two distinct in vitro human cancer cell models. Our results represent an important step forward in terms of economic valorization of Eucalyptus spp bark residues derived from forest industry.
Autores principais:Silvestre, Armando J. D.
Outros Autores:Silva, F. S.; Guerra, A. R.; Duarte, M. F.; Soares, B.; Freire, S. R.; Silvestre, A. J.D.; Calçada, C.; Pereira-Wilson, Cristina; Lima, Cristóvão Fernando Macedo
Ano:2015
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Silvestre, Armando J. D.
author2 Silva, F. S.
Guerra, A. R.
Duarte, M. F.
Soares, B.
Freire, S. R.
Silvestre, A. J.D.
Calçada, C.
Pereira-Wilson, Cristina
Lima, Cristóvão Fernando Macedo
author2_role author
author
author
author
author
author
author
author
author
author_facet Silvestre, Armando J. D.
Silva, F. S.
Guerra, A. R.
Duarte, M. F.
Soares, B.
Freire, S. R.
Silvestre, A. J.D.
Calçada, C.
Pereira-Wilson, Cristina
Lima, Cristóvão Fernando Macedo
author_role author
contributor_name_str_mv RepositóriUM - Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Silvestre, Armando J. D.\"},{\"Person.name\":\"Silva, F. S.\"},{\"Person.name\":\"Guerra, A. R.\"},{\"Person.name\":\"Duarte, M. F.\"},{\"Person.name\":\"Soares, B.\"},{\"Person.name\":\"Freire, S. R.\"},{\"Person.name\":\"Silvestre, A. J.D.\"},{\"Person.name\":\"Calçada, C.\"},{\"Person.name\":\"Pereira-Wilson, Cristina\"},{\"Person.name\":\"Lima, Cristóvão Fernando Macedo\"}]
datacite.contributors.contributor.contributorName.fl_str_mv RepositóriUM - Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Silvestre, Armando J. D.
Silva, F. S.
Guerra, A. R.
Duarte, M. F.
Soares, B.
Freire, S. R.
Silvestre, A. J.D.
Calçada, C.
Pereira-Wilson, Cristina
Lima, Cristóvão Fernando Macedo
datacite.date.Accepted.fl_str_mv 2015-01-01T00:00:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.titles.title.fl_str_mv New valorization strategies for eucalyptus spp. bark extracts
dc.contributor.none.fl_str_mv RepositóriUM - Universidade do Minho
dc.creator.none.fl_str_mv Silvestre, Armando J. D.
Silva, F. S.
Guerra, A. R.
Duarte, M. F.
Soares, B.
Freire, S. R.
Silvestre, A. J.D.
Calçada, C.
Pereira-Wilson, Cristina
Lima, Cristóvão Fernando Macedo
dc.date.Accepted.fl_str_mv 2015-01-01T00:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/50111
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv CRC Press/Balkema
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.title.fl_str_mv New valorization strategies for eucalyptus spp. bark extracts
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_5794
description The forest-based industry is important industrial sector in Europe, and particularly in Portugal. The increasingly higher demands for competitiveness, in forest-industry prompted the exploitation of different side-streams, such as bark residues. Within a biorefinery-based concept, these residues can be further refined to high value-added chemicals, with relevance for chemical and pharmaceutical industries. Results from our research team reveal that Eucalyptus globulus bark lipophilic extracts contain high quantities of triterpenoids (up to 12 g kg −1 bark), predominantly triterpenic acids (TAs), namely betulinic, betulonic, ursolic and oleanolic acids. Similar compo- sition has also been detected on Eucalyptus nitens outer bark. In the present work we report the chemical characterization of Eucalyptus spp. bark derived extracts, rich in TAs and the assessment of their antitumoral potential, using two distinct in vitro human cancer cell models. Our results represent an important step forward in terms of economic valorization of Eucalyptus spp bark residues derived from forest industry.
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eu_rights_str_mv restrictedAccess
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fulltext.url.fl_str_mv https://repositorium.uminho.pt/bitstreams/f04e2b21-1df6-47dd-a148-5596365778b3/download
id rum_5d32cae33b6063d3cd41ac2efdb8be1d
identifier.url.fl_str_mv https://hdl.handle.net/1822/50111
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instname_str Universidade do Minho
language eng
network_acronym_str rum
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oai_identifier_str oai:repositorium.uminho.pt:1822/50111
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Silvestre, Armando J. D.
Silva, F. S.
Guerra, A. R.
Duarte, M. F.
Soares, B.
Freire, S. R.
Silvestre, A. J.D.
Calçada, C.
Pereira-Wilson, Cristina
Lima, Cristóvão Fernando Macedo
publishDate 2015
publisher.none.fl_str_mv CRC Press/Balkema
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engCRC Press/BalkemaporThe forest-based industry is important industrial sector in Europe, and particularly in Portugal. The increasingly higher demands for competitiveness, in forest-industry prompted the exploitation of different side-streams, such as bark residues. Within a biorefinery-based concept, these residues can be further refined to high value-added chemicals, with relevance for chemical and pharmaceutical industries. Results from our research team reveal that Eucalyptus globulus bark lipophilic extracts contain high quantities of triterpenoids (up to 12 g kg −1 bark), predominantly triterpenic acids (TAs), namely betulinic, betulonic, ursolic and oleanolic acids. Similar compo- sition has also been detected on Eucalyptus nitens outer bark. In the present work we report the chemical characterization of Eucalyptus spp. bark derived extracts, rich in TAs and the assessment of their antitumoral potential, using two distinct in vitro human cancer cell models. Our results represent an important step forward in terms of economic valorization of Eucalyptus spp bark residues derived from forest industry.application/pdfporNew valorization strategies for eucalyptus spp. bark extractsSilvestre, Armando J. D.Silva, F. S.Guerra, A. R.Duarte, M. F.Soares, B.Freire, S. R.Silvestre, A. J.D.Calçada, C.Pereira-Wilson, CristinaLima, Cristóvão Fernando MacedoHostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISBNIsPartOf978113802882120152018-02-06T14:52:47Z2015-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/50111http://purl.org/coar/access_right/c_16ecrestricted access517015 bytesother research producthttp://purl.org/coar/resource_type/c_5794conference paperhttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorium.uminho.pt/bitstreams/f04e2b21-1df6-47dd-a148-5596365778b3/download
spellingShingle New valorization strategies for eucalyptus spp. bark extracts
Silvestre, Armando J. D.
status SINGLETON
title New valorization strategies for eucalyptus spp. bark extracts
title_full New valorization strategies for eucalyptus spp. bark extracts
title_fullStr New valorization strategies for eucalyptus spp. bark extracts
title_full_unstemmed New valorization strategies for eucalyptus spp. bark extracts
title_short New valorization strategies for eucalyptus spp. bark extracts
title_sort New valorization strategies for eucalyptus spp. bark extracts
url https://hdl.handle.net/1822/50111
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