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Kinetic modelling of autoimmune diseases

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Resumo:In this paper, we review previous results obtained by the authors, concerning the mathematical modelling of autoimmune diseases when the kinetic theory approach is used in order to describe the microscopic interactions between cells. Three cell populations are considered and the distribution function of each population depends on the biological activity variable defining the functional state relevant for that population. We revisit the wellposedness of the kinetic system and focus our study on the numerical simulations with the kinetic system in view of investigating the sensitivity of the solution to certain parameters of the model with biological significance.
Autores principais:Ramos, M. P. Machado
Outros Autores:Ribeiro, Carolina; Soares, A. J.
Assunto:Mathematical modelling Kinetic theory Cellular interactions Autoimmune diseases
Ano:2021
País:Portugal
Tipo de documento:capítulo de livro
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Ramos, M. P. Machado
author2 Ribeiro, Carolina
Soares, A. J.
author2_role author
author
author_facet Ramos, M. P. Machado
Ribeiro, Carolina
Soares, A. J.
author_role author
contributor_name_str_mv RepositóriUM - Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Ramos, M. P. Machado\"},{\"Person.name\":\"Ribeiro, Carolina\"},{\"Person.name\":\"Soares, A. J.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv RepositóriUM - Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Ramos, M. P. Machado
Ribeiro, Carolina
Soares, A. J.
datacite.date.Accepted.fl_str_mv 2021-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2024-01-18T09:32:25Z
datacite.date.embargoed.fl_str_mv 2024-01-18T09:32:25Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Mathematical modelling
Kinetic theory
Cellular interactions
Autoimmune diseases
datacite.titles.title.fl_str_mv Kinetic modelling of autoimmune diseases
dc.contributor.none.fl_str_mv RepositóriUM - Universidade do Minho
dc.creator.none.fl_str_mv Ramos, M. P. Machado
Ribeiro, Carolina
Soares, A. J.
dc.date.Accepted.fl_str_mv 2021-01-01T00:00:00Z
dc.date.available.fl_str_mv 2024-01-18T09:32:25Z
dc.date.embargoed.fl_str_mv 2024-01-18T09:32:25Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/88152
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Springer
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Mathematical modelling
Kinetic theory
Cellular interactions
Autoimmune diseases
dc.title.fl_str_mv Kinetic modelling of autoimmune diseases
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_3248
description In this paper, we review previous results obtained by the authors, concerning the mathematical modelling of autoimmune diseases when the kinetic theory approach is used in order to describe the microscopic interactions between cells. Three cell populations are considered and the distribution function of each population depends on the biological activity variable defining the functional state relevant for that population. We revisit the wellposedness of the kinetic system and focus our study on the numerical simulations with the kinetic system in view of investigating the sensitivity of the solution to certain parameters of the model with biological significance.
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eu_rights_str_mv openAccess
format bookPart
fulltext.url.fl_str_mv https://repositorium.uminho.pt/bitstreams/9281d1af-8026-4339-96c3-ac9c4794e9c4/download
id rum_62fcb8dfcf6f695ea8a161cf0f79679c
identifier.url.fl_str_mv https://hdl.handle.net/1822/88152
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/88152
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Ramos, M. P. Machado
Ribeiro, Carolina
Soares, A. J.
publishDate 2021
publisher.none.fl_str_mv Springer
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engSpringerporIn this paper, we review previous results obtained by the authors, concerning the mathematical modelling of autoimmune diseases when the kinetic theory approach is used in order to describe the microscopic interactions between cells. Three cell populations are considered and the distribution function of each population depends on the biological activity variable defining the functional state relevant for that population. We revisit the wellposedness of the kinetic system and focus our study on the numerical simulations with the kinetic system in view of investigating the sensitivity of the solution to certain parameters of the model with biological significance.application/pdfporKinetic modelling of autoimmune diseasesRamos, M. P. MachadoRibeiro, CarolinaSoares, A. J.HostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISBNIsPartOf978-3-030-82945-2ISSNIsPartOf2281-518XEISSNIsPartOf2281-5198DOIIsPartOf10.1007/978-3-030-82946-9_13EISBNIsPartOf978-3-030-82946-92024-01-18T09:32:25Z20212021-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/88152http://purl.org/coar/access_right/c_abf2open accessMathematical modellingKinetic theoryCellular interactionsAutoimmune diseases560381 bytesliteraturehttp://purl.org/coar/resource_type/c_3248book parthttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/9281d1af-8026-4339-96c3-ac9c4794e9c4/download
spellingShingle Kinetic modelling of autoimmune diseases
Ramos, M. P. Machado
Mathematical modelling
Kinetic theory
Cellular interactions
Autoimmune diseases
status SINGLETON
subject.fl_str_mv Mathematical modelling
Kinetic theory
Cellular interactions
Autoimmune diseases
title Kinetic modelling of autoimmune diseases
title_full Kinetic modelling of autoimmune diseases
title_fullStr Kinetic modelling of autoimmune diseases
title_full_unstemmed Kinetic modelling of autoimmune diseases
title_short Kinetic modelling of autoimmune diseases
title_sort Kinetic modelling of autoimmune diseases
topic Mathematical modelling
Kinetic theory
Cellular interactions
Autoimmune diseases
topic_facet Mathematical modelling
Kinetic theory
Cellular interactions
Autoimmune diseases
url https://hdl.handle.net/1822/88152
visible 1