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Ohmic heating-based extraction of biocompounds from cocoa bean shell

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Resumo:Cocoa bean shell (CBS), a by-product of the chocolate industry, was employed as substrate for the sustainable recovery of bioactive compounds using ohmic heating (OH). Total phenolic content and antioxidant activity of the treated CBS were optimized by experimental design. Maximum extraction of antioxidant phenolic compounds (23mg GAE/g CBS) was obtained at 67°C, 50min and 44% ethanol (v/v). The antioxidant activity of the extracts obtained under of the central point conditions was 284.5M Fe2+/g extract (FRAP) and 36.4MTE/g extract (DPPH). The use of OH increased the extraction of bioactive phenolic compounds when compared to the conventional process (CH) (approximately 40%). An increased on the chemical antioxidant activity was also observed, ranging from 4 to 20%. The metabolic activity of the extracts obtained by the two methods (OH and CH) was evaluated in non-tumoral (HEK293T and L929) and tumoral cell lines (Caco-2, HT-29, and HeLa). The CBS extracts presented low toxicity in non-tumoral cells and ROS preventive effects. These characteristics make them ideal to be used in food processing and formulation, as well as nutraceutical products due to their antioxidant protection. The use of OH results in an extract with higher phenolic content and higher antioxidant activity and low environmental impact.
Autores principais:Sánchez, M.
Outros Autores:Santos, Pedro Miguel Ferreira; Dias, Joana Sofia Gomes; Botelho, C. M.; Laca, A.; Rocha, Cristina M. R.
Assunto:Cocoa bean shell Antioxidants Phenolic compounds Ohmic heating Green technology
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Sánchez, M.
author2 Santos, Pedro Miguel Ferreira
Dias, Joana Sofia Gomes
Botelho, C. M.
Laca, A.
Rocha, Cristina M. R.
author2_role author
author
author
author
author
author_facet Sánchez, M.
Santos, Pedro Miguel Ferreira
Dias, Joana Sofia Gomes
Botelho, C. M.
Laca, A.
Rocha, Cristina M. R.
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Sánchez, M.\"},{\"Person.name\":\"Santos, Pedro Miguel Ferreira\"},{\"Person.name\":\"Dias, Joana Sofia Gomes\"},{\"Person.name\":\"Botelho, C. M.\"},{\"Person.name\":\"Laca, A.\"},{\"Person.name\":\"Rocha, Cristina M. R.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Sánchez, M.
Santos, Pedro Miguel Ferreira
Dias, Joana Sofia Gomes
Botelho, C. M.
Laca, A.
Rocha, Cristina M. R.
datacite.date.Accepted.fl_str_mv 2023-06-26T00:00:00Z
datacite.date.available.fl_str_mv 2023-06-30T17:59:34Z
datacite.date.embargoed.fl_str_mv 2023-06-30T17:59:34Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Cocoa bean shell
Antioxidants
Phenolic compounds
Ohmic heating
Green technology
datacite.titles.title.fl_str_mv Ohmic heating-based extraction of biocompounds from cocoa bean shell
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Sánchez, M.
Santos, Pedro Miguel Ferreira
Dias, Joana Sofia Gomes
Botelho, C. M.
Laca, A.
Rocha, Cristina M. R.
dc.date.Accepted.fl_str_mv 2023-06-26T00:00:00Z
dc.date.available.fl_str_mv 2023-06-30T17:59:34Z
dc.date.embargoed.fl_str_mv 2023-06-30T17:59:34Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/85289
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Cocoa bean shell
Antioxidants
Phenolic compounds
Ohmic heating
Green technology
dc.title.fl_str_mv Ohmic heating-based extraction of biocompounds from cocoa bean shell
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Cocoa bean shell (CBS), a by-product of the chocolate industry, was employed as substrate for the sustainable recovery of bioactive compounds using ohmic heating (OH). Total phenolic content and antioxidant activity of the treated CBS were optimized by experimental design. Maximum extraction of antioxidant phenolic compounds (23mg GAE/g CBS) was obtained at 67°C, 50min and 44% ethanol (v/v). The antioxidant activity of the extracts obtained under of the central point conditions was 284.5M Fe2+/g extract (FRAP) and 36.4MTE/g extract (DPPH). The use of OH increased the extraction of bioactive phenolic compounds when compared to the conventional process (CH) (approximately 40%). An increased on the chemical antioxidant activity was also observed, ranging from 4 to 20%. The metabolic activity of the extracts obtained by the two methods (OH and CH) was evaluated in non-tumoral (HEK293T and L929) and tumoral cell lines (Caco-2, HT-29, and HeLa). The CBS extracts presented low toxicity in non-tumoral cells and ROS preventive effects. These characteristics make them ideal to be used in food processing and formulation, as well as nutraceutical products due to their antioxidant protection. The use of OH results in an extract with higher phenolic content and higher antioxidant activity and low environmental impact.
dirty 0
eu_rights_str_mv openAccess
format article
fulltext.url.fl_str_mv https://prod-dspace.uminho.pt/bitstreams/01ee0277-a191-4359-ace3-335bf9b50c7c/download
id rum_7aed315ddc0bf3c00a4314e42949300c
identifier.url.fl_str_mv https://hdl.handle.net/1822/85289
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/85289
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Sánchez, M.
Santos, Pedro Miguel Ferreira
Dias, Joana Sofia Gomes
Botelho, C. M.
Laca, A.
Rocha, Cristina M. R.
publishDate 2023
publisher.none.fl_str_mv Elsevier
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engElsevierporCocoa bean shell (CBS), a by-product of the chocolate industry, was employed as substrate for the sustainable recovery of bioactive compounds using ohmic heating (OH). Total phenolic content and antioxidant activity of the treated CBS were optimized by experimental design. Maximum extraction of antioxidant phenolic compounds (23mg GAE/g CBS) was obtained at 67°C, 50min and 44% ethanol (v/v). The antioxidant activity of the extracts obtained under of the central point conditions was 284.5M Fe2+/g extract (FRAP) and 36.4MTE/g extract (DPPH). The use of OH increased the extraction of bioactive phenolic compounds when compared to the conventional process (CH) (approximately 40%). An increased on the chemical antioxidant activity was also observed, ranging from 4 to 20%. The metabolic activity of the extracts obtained by the two methods (OH and CH) was evaluated in non-tumoral (HEK293T and L929) and tumoral cell lines (Caco-2, HT-29, and HeLa). The CBS extracts presented low toxicity in non-tumoral cells and ROS preventive effects. These characteristics make them ideal to be used in food processing and formulation, as well as nutraceutical products due to their antioxidant protection. The use of OH results in an extract with higher phenolic content and higher antioxidant activity and low environmental impact.application/pdfporOhmic heating-based extraction of biocompounds from cocoa bean shellSánchez, M.Santos, Pedro Miguel FerreiraDias, Joana Sofia GomesBotelho, C. M.Laca, A.Rocha, Cristina M. R.HostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf2212-4292DOIIsPartOf10.1016/j.fbio.2023.1028862023-06-30T17:59:34Z2023-06-262023-06-26T11:03:51Z2023-06-26T00:00:00ZHandlehttps://hdl.handle.net/1822/85289http://purl.org/coar/access_right/c_abf2open accessCocoa bean shellAntioxidantsPhenolic compoundsOhmic heatingGreen technology1518118 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/01ee0277-a191-4359-ace3-335bf9b50c7c/download
spellingShingle Ohmic heating-based extraction of biocompounds from cocoa bean shell
Sánchez, M.
Cocoa bean shell
Antioxidants
Phenolic compounds
Ohmic heating
Green technology
status SINGLETON
subject.fl_str_mv Cocoa bean shell
Antioxidants
Phenolic compounds
Ohmic heating
Green technology
title Ohmic heating-based extraction of biocompounds from cocoa bean shell
title_full Ohmic heating-based extraction of biocompounds from cocoa bean shell
title_fullStr Ohmic heating-based extraction of biocompounds from cocoa bean shell
title_full_unstemmed Ohmic heating-based extraction of biocompounds from cocoa bean shell
title_short Ohmic heating-based extraction of biocompounds from cocoa bean shell
title_sort Ohmic heating-based extraction of biocompounds from cocoa bean shell
topic Cocoa bean shell
Antioxidants
Phenolic compounds
Ohmic heating
Green technology
topic_facet Cocoa bean shell
Antioxidants
Phenolic compounds
Ohmic heating
Green technology
url https://hdl.handle.net/1822/85289
visible 1