Publicação
Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use
| Resumo: | Coagulase-negative staphylococci (CoNS) are commensal bacteria of the human skin and mucosal membranes. The incidence of nosocomial infections caused by these species is on the rise, leading to a potential increase in antibiotic tolerance and resistance. Phages are emerging as a promising alternative to combat CoNS infections. Scientists are isolating phages infecting CoNS with a particular interest in S. epidermidis. This review compiles and analyses CoNS phages for several parameters including source, geographical location, host species, morphological diversity, and genomic diversity. Additionally, recent studies have highlighted the potential of these phages based on host range, in vitro evaluation of performance and stability, and interaction with biofilms. This comprehensive analysis enables a better understanding of the steps involved in using these phages for therapeutic purposes. |
|---|---|
| Autores principais: | Lopes, Maria Beatriz Afonso Sequeira |
| Outros Autores: | Silva, Maria Daniela Ferreira; Azeredo, Joana; Melo, Luís Daniel Rodrigues |
| Assunto: | Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| Ano: | 2025 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1866877842709544960 |
|---|---|
| author | Lopes, Maria Beatriz Afonso Sequeira |
| author2 | Silva, Maria Daniela Ferreira Azeredo, Joana Melo, Luís Daniel Rodrigues |
| author2_role | author author author |
| author_facet | Lopes, Maria Beatriz Afonso Sequeira Silva, Maria Daniela Ferreira Azeredo, Joana Melo, Luís Daniel Rodrigues |
| author_role | author |
| contributor_name_str_mv | Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Lopes, Maria Beatriz Afonso Sequeira\"},{\"Person.name\":\"Silva, Maria Daniela Ferreira\"},{\"Person.name\":\"Azeredo, Joana\"},{\"Person.name\":\"Melo, Luís Daniel Rodrigues\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Lopes, Maria Beatriz Afonso Sequeira Silva, Maria Daniela Ferreira Azeredo, Joana Melo, Luís Daniel Rodrigues |
| datacite.date.Accepted.fl_str_mv | 2025-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2024-11-26T08:16:08Z |
| datacite.date.embargoed.fl_str_mv | 2024-11-26T08:16:08Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| datacite.titles.title.fl_str_mv | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| dc.contributor.none.fl_str_mv | Universidade do Minho |
| dc.creator.none.fl_str_mv | Lopes, Maria Beatriz Afonso Sequeira Silva, Maria Daniela Ferreira Azeredo, Joana Melo, Luís Daniel Rodrigues |
| dc.date.Accepted.fl_str_mv | 2025-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2024-11-26T08:16:08Z |
| dc.date.embargoed.fl_str_mv | 2024-11-26T08:16:08Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/93725 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Elsevier B.V. |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| dc.title.fl_str_mv | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Coagulase-negative staphylococci (CoNS) are commensal bacteria of the human skin and mucosal membranes. The incidence of nosocomial infections caused by these species is on the rise, leading to a potential increase in antibiotic tolerance and resistance. Phages are emerging as a promising alternative to combat CoNS infections. Scientists are isolating phages infecting CoNS with a particular interest in S. epidermidis. This review compiles and analyses CoNS phages for several parameters including source, geographical location, host species, morphological diversity, and genomic diversity. Additionally, recent studies have highlighted the potential of these phages based on host range, in vitro evaluation of performance and stability, and interaction with biofilms. This comprehensive analysis enables a better understanding of the steps involved in using these phages for therapeutic purposes. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://prod-dspace.uminho.pt/bitstreams/d5fc52a3-eb60-4da0-8ccc-8136d945b223/download |
| id | rum_7b9aa3d150068fb33db0680aaa64ddc4 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/93725 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/93725 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Lopes, Maria Beatriz Afonso Sequeira Silva, Maria Daniela Ferreira Azeredo, Joana Melo, Luís Daniel Rodrigues |
| publishDate | 2025 |
| publisher.none.fl_str_mv | Elsevier B.V. |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engElsevier B.V.porCoagulase-negative staphylococci (CoNS) are commensal bacteria of the human skin and mucosal membranes. The incidence of nosocomial infections caused by these species is on the rise, leading to a potential increase in antibiotic tolerance and resistance. Phages are emerging as a promising alternative to combat CoNS infections. Scientists are isolating phages infecting CoNS with a particular interest in S. epidermidis. This review compiles and analyses CoNS phages for several parameters including source, geographical location, host species, morphological diversity, and genomic diversity. Additionally, recent studies have highlighted the potential of these phages based on host range, in vitro evaluation of performance and stability, and interaction with biofilms. This comprehensive analysis enables a better understanding of the steps involved in using these phages for therapeutic purposes.application/pdfporCoagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic useLopes, Maria Beatriz Afonso SequeiraSilva, Maria Daniela FerreiraAzeredo, JoanaMelo, Luís Daniel RodriguesHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf0944-5013DOIIsPartOf10.1016/j.micres.2024.1279442024-11-26T08:16:08Z2025-012024-11-25T22:59:40Z2025-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/93725http://purl.org/coar/access_right/c_abf2open accessBacteriophagesCoagulase-negative staphylococciGenomic diversityin vitro studies5437591 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/d5fc52a3-eb60-4da0-8ccc-8136d945b223/download |
| spellingShingle | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use Lopes, Maria Beatriz Afonso Sequeira Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| status | SINGLETON |
| subject.fl_str_mv | Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| title | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| title_full | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| title_fullStr | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| title_full_unstemmed | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| title_short | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| title_sort | Coagulase-Negative Staphylococci phages panorama: genomic diversity and in vitro studies for a therapeutic use |
| topic | Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| topic_facet | Bacteriophages Coagulase-negative staphylococci Genomic diversity in vitro studies |
| url | https://hdl.handle.net/1822/93725 |
| visible | 1 |