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Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value

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Resumo:The development of molecular diagnostics that detect both the presence of Mycobacterium tuberculosis in clinical samples and drug resistance-conferring mutations promises to revolutionize patient care and interrupt transmission by ensuring early diagnosis. However, these tools require the identification of genetic determinants of resistance to the full range of antituberculosis drugs.
Autores principais:Farhat, Maha R.
Outros Autores:Sultana, Razvan; Iartchouk, Oleg; Bozeman, Sam; Galagan, James; Sisk, Peter; Stolte, Christian; Nebenzahl-Guimaraes, Hanna; Jacobson, Karen; Sloutsky, Alexander; Kaur, Devinder; Posey, James; Kreiswirth, Barry N.; Kurepina, Natalia; Rigouts, Leen; Streicher, Elizabeth M.; Victor, Tommie C.; Warren, Robin M.; van Soolingen, Dick; Murray, Megan
Assunto:Antitubercular Agents Drug Resistance, Multiple, Bacterial Genes, Bacterial Humans Mutation Mycobacterium tuberculosis Sequence Analysis, DNA Tuberculosis, Multidrug-Resistant Molecular Diagnostic Techniques multidrug-resistant tuberculosis molecular diagnostics sensitivity and specificity Ciências Médicas::Medicina Básica
Ano:2016
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho

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