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Bowel preparation for small bowel capsule endoscopy - The later, the better!

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Resumo:In small bowel capsule endoscopy (SBCE), the presence of residue may compromise diagnostic accuracy. Background In small bowel capsule endoscopy (SBCE), the presence of residue may compromise diagnostic accuracy. Aims To assess differences in quality of visualisation and diagnostic yield of SBCE using 3 different preparation protocols. Methods Prospective, randomized, blind, pilot study. Protocol A:Clear liquids diet the day before the examination with fasting from 8p.m.; Protocol B:Protocol A + 2 pouches of Moviprep®(polyethylene glycol electrolyte solution + sodium ascorbate) in 1 L of water from 8p.m. of the day before the examination; Protocol C: Protocol A + 2 pouches of Moviprep® in 1 L of water consumed after real-time confirmation of capsule arrival at small bowel. Small bowel preparation was classified by two experienced physicians, considering the percentage of the examination during which mucosal observation was adequate: Excellent(>90%); Good(90–75%); Fair(75–50%); Poor(<50%). Results 101 patients randomized to the 3 protocols (A 37, B 31, C 33 patients). Protocol C had an excellent/good small bowel preparation in a higher percentage of examinations for both readers(Reader 1-A:37.8% vs B:45.2% vs C:78.8%, p = 0.002 and Reader 2 –A:37.8% vs B:41.9% vs C:75.8%, p = 0.003). Also, protocol C had a higher detection of angioectasia (A:5.4% vs B:9.7% vs C:27.3%, p = 0.022). Conclusions The administration of Moviprep® after the capsule had reached the small bowel was associated with a better small bowel preparation and a higher detection of angioectasia.
Autores principais:Xavier, S.
Outros Autores:Rosa, B.; Monteiro, S.; Arieira, C.; Magalhães, R.; Cúrdia Gonçalves, T.; Boal Carvalho, P.; Magalhães, J.; Moreira, M. J.; Cotter, José Almeida Berkeley
Assunto:Adult Aged Capsule Endoscopy Cathartics Female Gastrointestinal Transit Humans Intestine, Small Male Middle Aged Pilot Projects Polyethylene Glycols Prospective Studies Fasting Bowel preparation Diagnostic yield Small bowel capsule endoscopy
Ano:2019
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Xavier, S.
author2 Rosa, B.
Monteiro, S.
Arieira, C.
Magalhães, R.
Cúrdia Gonçalves, T.
Boal Carvalho, P.
Magalhães, J.
Moreira, M. J.
Cotter, José Almeida Berkeley
author2_role author
author
author
author
author
author
author
author
author
author_facet Xavier, S.
Rosa, B.
Monteiro, S.
Arieira, C.
Magalhães, R.
Cúrdia Gonçalves, T.
Boal Carvalho, P.
Magalhães, J.
Moreira, M. J.
Cotter, José Almeida Berkeley
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Xavier, S.\"},{\"Person.name\":\"Rosa, B.\"},{\"Person.name\":\"Monteiro, S.\"},{\"Person.name\":\"Arieira, C.\"},{\"Person.name\":\"Magalhães, R.\"},{\"Person.name\":\"Cúrdia Gonçalves, T.\"},{\"Person.name\":\"Boal Carvalho, P.\"},{\"Person.name\":\"Magalhães, J.\"},{\"Person.name\":\"Moreira, M. J.\"},{\"Person.name\":\"Cotter, José Almeida Berkeley\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Xavier, S.
Rosa, B.
Monteiro, S.
Arieira, C.
Magalhães, R.
Cúrdia Gonçalves, T.
Boal Carvalho, P.
Magalhães, J.
Moreira, M. J.
Cotter, José Almeida Berkeley
datacite.date.Accepted.fl_str_mv 2019-10-01T00:00:00Z
datacite.date.embargoed.fl_str_mv 10000-01-01T00:00:00Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Adult
Aged
Capsule Endoscopy
Cathartics
Female
Gastrointestinal Transit
Humans
Intestine, Small
Male
Middle Aged
Pilot Projects
Polyethylene Glycols
Prospective Studies
Fasting
Bowel preparation
Diagnostic yield
Small bowel capsule endoscopy
datacite.titles.title.fl_str_mv Bowel preparation for small bowel capsule endoscopy - The later, the better!
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Xavier, S.
Rosa, B.
Monteiro, S.
Arieira, C.
Magalhães, R.
Cúrdia Gonçalves, T.
Boal Carvalho, P.
Magalhães, J.
Moreira, M. J.
Cotter, José Almeida Berkeley
dc.date.Accepted.fl_str_mv 2019-10-01T00:00:00Z
dc.date.embargoed.fl_str_mv 10000-01-01T00:00:00Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/67405
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Adult
Aged
Capsule Endoscopy
Cathartics
Female
Gastrointestinal Transit
Humans
Intestine, Small
Male
Middle Aged
Pilot Projects
Polyethylene Glycols
Prospective Studies
Fasting
Bowel preparation
Diagnostic yield
Small bowel capsule endoscopy
dc.title.fl_str_mv Bowel preparation for small bowel capsule endoscopy - The later, the better!
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description In small bowel capsule endoscopy (SBCE), the presence of residue may compromise diagnostic accuracy. Background In small bowel capsule endoscopy (SBCE), the presence of residue may compromise diagnostic accuracy. Aims To assess differences in quality of visualisation and diagnostic yield of SBCE using 3 different preparation protocols. Methods Prospective, randomized, blind, pilot study. Protocol A:Clear liquids diet the day before the examination with fasting from 8p.m.; Protocol B:Protocol A + 2 pouches of Moviprep®(polyethylene glycol electrolyte solution + sodium ascorbate) in 1 L of water from 8p.m. of the day before the examination; Protocol C: Protocol A + 2 pouches of Moviprep® in 1 L of water consumed after real-time confirmation of capsule arrival at small bowel. Small bowel preparation was classified by two experienced physicians, considering the percentage of the examination during which mucosal observation was adequate: Excellent(>90%); Good(90–75%); Fair(75–50%); Poor(<50%). Results 101 patients randomized to the 3 protocols (A 37, B 31, C 33 patients). Protocol C had an excellent/good small bowel preparation in a higher percentage of examinations for both readers(Reader 1-A:37.8% vs B:45.2% vs C:78.8%, p = 0.002 and Reader 2 –A:37.8% vs B:41.9% vs C:75.8%, p = 0.003). Also, protocol C had a higher detection of angioectasia (A:5.4% vs B:9.7% vs C:27.3%, p = 0.022). Conclusions The administration of Moviprep® after the capsule had reached the small bowel was associated with a better small bowel preparation and a higher detection of angioectasia.
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fulltext.url.fl_str_mv https://prod-dspace.uminho.pt/bitstreams/66b41ea2-83e6-4914-86ea-cdf2054f58ee/download
id rum_91ded4e06d63db89eb42e8f9fd1176b1
identifier.url.fl_str_mv https://hdl.handle.net/1822/67405
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
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oai_identifier_str oai:repositorium.uminho.pt:1822/67405
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Xavier, S.
Rosa, B.
Monteiro, S.
Arieira, C.
Magalhães, R.
Cúrdia Gonçalves, T.
Boal Carvalho, P.
Magalhães, J.
Moreira, M. J.
Cotter, José Almeida Berkeley
publishDate 2019
publisher.none.fl_str_mv Elsevier
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engElsevierporIn small bowel capsule endoscopy (SBCE), the presence of residue may compromise diagnostic accuracy. Background In small bowel capsule endoscopy (SBCE), the presence of residue may compromise diagnostic accuracy. Aims To assess differences in quality of visualisation and diagnostic yield of SBCE using 3 different preparation protocols. Methods Prospective, randomized, blind, pilot study. Protocol A:Clear liquids diet the day before the examination with fasting from 8p.m.; Protocol B:Protocol A + 2 pouches of Moviprep®(polyethylene glycol electrolyte solution + sodium ascorbate) in 1 L of water from 8p.m. of the day before the examination; Protocol C: Protocol A + 2 pouches of Moviprep® in 1 L of water consumed after real-time confirmation of capsule arrival at small bowel. Small bowel preparation was classified by two experienced physicians, considering the percentage of the examination during which mucosal observation was adequate: Excellent(>90%); Good(90–75%); Fair(75–50%); Poor(<50%). Results 101 patients randomized to the 3 protocols (A 37, B 31, C 33 patients). Protocol C had an excellent/good small bowel preparation in a higher percentage of examinations for both readers(Reader 1-A:37.8% vs B:45.2% vs C:78.8%, p = 0.002 and Reader 2 –A:37.8% vs B:41.9% vs C:75.8%, p = 0.003). Also, protocol C had a higher detection of angioectasia (A:5.4% vs B:9.7% vs C:27.3%, p = 0.022). Conclusions The administration of Moviprep® after the capsule had reached the small bowel was associated with a better small bowel preparation and a higher detection of angioectasia.application/pdfporBowel preparation for small bowel capsule endoscopy - The later, the better!Xavier, S.Rosa, B.Monteiro, S.Arieira, C.Magalhães, R.Cúrdia Gonçalves, T.Boal Carvalho, P.Magalhães, J.Moreira, M. J.Cotter, José Almeida BerkeleyHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1590-8658DOIIsPartOf10.1016/j.dld.2019.04.0142019-102019-10-01T00:00:00Z10000-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/67405http://purl.org/coar/access_right/c_16ecrestricted accessAdultAgedCapsule EndoscopyCatharticsFemaleGastrointestinal TransitHumansIntestine, SmallMaleMiddle AgedPilot ProjectsPolyethylene GlycolsProspective StudiesFastingBowel preparationDiagnostic yieldSmall bowel capsule endoscopy365361 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_f1cfapplication/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/66b41ea2-83e6-4914-86ea-cdf2054f58ee/download
spellingShingle Bowel preparation for small bowel capsule endoscopy - The later, the better!
Xavier, S.
Adult
Aged
Capsule Endoscopy
Cathartics
Female
Gastrointestinal Transit
Humans
Intestine, Small
Male
Middle Aged
Pilot Projects
Polyethylene Glycols
Prospective Studies
Fasting
Bowel preparation
Diagnostic yield
Small bowel capsule endoscopy
status SINGLETON
subject.fl_str_mv Adult
Aged
Capsule Endoscopy
Cathartics
Female
Gastrointestinal Transit
Humans
Intestine, Small
Male
Middle Aged
Pilot Projects
Polyethylene Glycols
Prospective Studies
Fasting
Bowel preparation
Diagnostic yield
Small bowel capsule endoscopy
title Bowel preparation for small bowel capsule endoscopy - The later, the better!
title_full Bowel preparation for small bowel capsule endoscopy - The later, the better!
title_fullStr Bowel preparation for small bowel capsule endoscopy - The later, the better!
title_full_unstemmed Bowel preparation for small bowel capsule endoscopy - The later, the better!
title_short Bowel preparation for small bowel capsule endoscopy - The later, the better!
title_sort Bowel preparation for small bowel capsule endoscopy - The later, the better!
topic Adult
Aged
Capsule Endoscopy
Cathartics
Female
Gastrointestinal Transit
Humans
Intestine, Small
Male
Middle Aged
Pilot Projects
Polyethylene Glycols
Prospective Studies
Fasting
Bowel preparation
Diagnostic yield
Small bowel capsule endoscopy
topic_facet Adult
Aged
Capsule Endoscopy
Cathartics
Female
Gastrointestinal Transit
Humans
Intestine, Small
Male
Middle Aged
Pilot Projects
Polyethylene Glycols
Prospective Studies
Fasting
Bowel preparation
Diagnostic yield
Small bowel capsule endoscopy
url https://hdl.handle.net/1822/67405
visible 1