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Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts

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Resumo:Oleoresin extraction from fennel seeds using a supercritical fluid extraction (SFE) was carried out. Box–Behnken experimental design was used to optimize the SFE variables: pressure (10, 17.5, and 25 MPa), temperature (313.15, 323.15, and 333.15 K) and time of extraction (1, 2.5, and 4 h). Different percentages of methanol (0, 3, and 6%) were also evaluated to improve the extraction of the corresponding volatile compounds. Besides volatile profile characterization of fennel seeds, the amount of estragole was determined (by gas chromatography-flame ionization detector (GC-FID)) due to its recent concern in being considered a potential carcinogen agent. The optimal values of SFE variables for methanol extracts were high levels of pressure (24 MPa), 333.15 K of temperature, 3.41 h of extraction time, and an intermediate value of methanol percentage (3%), obtaining an optimal value of 1320 ± 260 mg of estragole/kg dry plant. The volatile profile of the methanol extracts was evaluated by gas chromatography–mass spectrometry (GC–MS) obtaining mainly, terpenes, phenyl derivatives, and fatty acids.
Autores principais:Rodríguez-Solana, Raquel
Outros Autores:Salgado, José Manuel; Domínguez, José Manuel; Cortés-Diéguez, Sara
Assunto:Box–Behnken design Essential oils Estragole Fennel SFE
Ano:2014
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Rodríguez-Solana, Raquel
author2 Salgado, José Manuel
Domínguez, José Manuel
Cortés-Diéguez, Sara
author2_role author
author
author
author_facet Rodríguez-Solana, Raquel
Salgado, José Manuel
Domínguez, José Manuel
Cortés-Diéguez, Sara
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Rodríguez-Solana, Raquel\"},{\"Person.name\":\"Salgado, José Manuel\"},{\"Person.name\":\"Domínguez, José Manuel\"},{\"Person.name\":\"Cortés-Diéguez, Sara\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Rodríguez-Solana, Raquel
Salgado, José Manuel
Domínguez, José Manuel
Cortés-Diéguez, Sara
datacite.date.Accepted.fl_str_mv 2014-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2014-12-11T12:25:07Z
datacite.date.embargoed.fl_str_mv 2014-12-11T12:25:07Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Box–Behnken design
Essential oils
Estragole
Fennel
SFE
datacite.titles.title.fl_str_mv Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Rodríguez-Solana, Raquel
Salgado, José Manuel
Domínguez, José Manuel
Cortés-Diéguez, Sara
dc.date.Accepted.fl_str_mv 2014-01-01T00:00:00Z
dc.date.available.fl_str_mv 2014-12-11T12:25:07Z
dc.date.embargoed.fl_str_mv 2014-12-11T12:25:07Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/31839
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Elsevier B.V.
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Box–Behnken design
Essential oils
Estragole
Fennel
SFE
dc.title.fl_str_mv Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Oleoresin extraction from fennel seeds using a supercritical fluid extraction (SFE) was carried out. Box–Behnken experimental design was used to optimize the SFE variables: pressure (10, 17.5, and 25 MPa), temperature (313.15, 323.15, and 333.15 K) and time of extraction (1, 2.5, and 4 h). Different percentages of methanol (0, 3, and 6%) were also evaluated to improve the extraction of the corresponding volatile compounds. Besides volatile profile characterization of fennel seeds, the amount of estragole was determined (by gas chromatography-flame ionization detector (GC-FID)) due to its recent concern in being considered a potential carcinogen agent. The optimal values of SFE variables for methanol extracts were high levels of pressure (24 MPa), 333.15 K of temperature, 3.41 h of extraction time, and an intermediate value of methanol percentage (3%), obtaining an optimal value of 1320 ± 260 mg of estragole/kg dry plant. The volatile profile of the methanol extracts was evaluated by gas chromatography–mass spectrometry (GC–MS) obtaining mainly, terpenes, phenyl derivatives, and fatty acids.
dirty 0
eu_rights_str_mv restrictedAccess
format article
fulltext.url.fl_str_mv https://prod-dspace.uminho.pt/bitstreams/5c4c81f9-f976-4966-9168-cc2d00aa7094/download
id rum_92e16632e15b94c73021bd9dc3e3d2e3
identifier.url.fl_str_mv https://hdl.handle.net/1822/31839
instacron_str repositorium
institution Universidade do Minho
instname_str Universidade do Minho
language eng
network_acronym_str rum
network_name_str RepositóriUM - Universidade do Minho
oai_identifier_str oai:repositorium.uminho.pt:1822/31839
organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Rodríguez-Solana, Raquel
Salgado, José Manuel
Domínguez, José Manuel
Cortés-Diéguez, Sara
publishDate 2014
publisher.none.fl_str_mv Elsevier B.V.
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
service_str_mv urn:repositoryAcronym:rum
spelling engElsevier B.V.porOleoresin extraction from fennel seeds using a supercritical fluid extraction (SFE) was carried out. Box–Behnken experimental design was used to optimize the SFE variables: pressure (10, 17.5, and 25 MPa), temperature (313.15, 323.15, and 333.15 K) and time of extraction (1, 2.5, and 4 h). Different percentages of methanol (0, 3, and 6%) were also evaluated to improve the extraction of the corresponding volatile compounds. Besides volatile profile characterization of fennel seeds, the amount of estragole was determined (by gas chromatography-flame ionization detector (GC-FID)) due to its recent concern in being considered a potential carcinogen agent. The optimal values of SFE variables for methanol extracts were high levels of pressure (24 MPa), 333.15 K of temperature, 3.41 h of extraction time, and an intermediate value of methanol percentage (3%), obtaining an optimal value of 1320 ± 260 mg of estragole/kg dry plant. The volatile profile of the methanol extracts was evaluated by gas chromatography–mass spectrometry (GC–MS) obtaining mainly, terpenes, phenyl derivatives, and fatty acids.application/pdfporEstragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extractsRodríguez-Solana, RaquelSalgado, José ManuelDomínguez, José ManuelCortés-Diéguez, SaraHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf0926-6690DOIIsPartOf10.1016/j.indcrop.2014.05.0272014-12-11T12:25:07Z2014-01-012014-11-28T17:47:48Z2014-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/31839http://purl.org/coar/access_right/c_16ecrestricted accessBox–Behnken designEssential oilsEstragoleFennelSFE1177809 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/5c4c81f9-f976-4966-9168-cc2d00aa7094/download
spellingShingle Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
Rodríguez-Solana, Raquel
Box–Behnken design
Essential oils
Estragole
Fennel
SFE
status SINGLETON
subject.fl_str_mv Box–Behnken design
Essential oils
Estragole
Fennel
SFE
title Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
title_full Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
title_fullStr Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
title_full_unstemmed Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
title_short Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
title_sort Estragole quantity optimization from fennel seeds by supercritical fluid extraction (carbon dioxide–methanol) using a Box–Behnken design : characterization of fennel extracts
topic Box–Behnken design
Essential oils
Estragole
Fennel
SFE
topic_facet Box–Behnken design
Essential oils
Estragole
Fennel
SFE
url https://hdl.handle.net/1822/31839
visible 1