Publicação
Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications
| Resumo: | In this work, the authors propose a new quick sol–gel procedure for bioglass nanoparticles production containing 10% mol of silver (AgBGs). These new AgBGs are characterized by Zeta potential analysis, scanning electron microscopy with X-ray microanalysis (SEM/EDS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and microbiological tests to confirm their bioactive and antibacterial properties. SEM shows that the average particle size is less than 200 nm and EDS confirms the successful incorporation of Ag2O in the bioglass matrix. XRD confirms the amorphous nature of the AgBGs and, after SBF immersion, reveals their bioactive behavior with the presence of crystalline phase of calcium silicate and phosphorus oxide, which are also detected by FTIR analysis. FTIR also confirms the formation of typical siloxane bonds resulting from the condensation of silicate glass. Lastly, it is found that the developed AgBGs has an antibacterial effect against two different types of bacteria, thus demonstrating their ability to reduce the bacterial infection within 16 h. |
|---|---|
| Autores principais: | Vale, Ana Catarina |
| Outros Autores: | Carvalho, Ana Luísa; Barbosa, Ana Margarida Martins; Torrado, Egídio; Mano, J. F.; Alves, N. M. |
| Assunto: | Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| Ano: | 2018 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1866877871690088448 |
|---|---|
| author | Vale, Ana Catarina |
| author2 | Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
| author2_role | author author author author author |
| author_facet | Vale, Ana Catarina Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
| author_role | author |
| contributor_name_str_mv | Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Vale, Ana Catarina\"},{\"Person.name\":\"Carvalho, Ana Luísa\"},{\"Person.name\":\"Barbosa, Ana Margarida Martins\"},{\"Person.name\":\"Torrado, Egídio\"},{\"Person.name\":\"Mano, J. F.\"},{\"Person.name\":\"Alves, N. M.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Vale, Ana Catarina Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
| datacite.date.Accepted.fl_str_mv | 2018-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2018-02-22T10:08:56Z |
| datacite.date.embargoed.fl_str_mv | 2018-02-22T10:08:56Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| datacite.titles.title.fl_str_mv | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| dc.contributor.none.fl_str_mv | Universidade do Minho |
| dc.creator.none.fl_str_mv | Vale, Ana Catarina Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
| dc.date.Accepted.fl_str_mv | 2018-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2018-02-22T10:08:56Z |
| dc.date.embargoed.fl_str_mv | 2018-02-22T10:08:56Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/50827 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Wiley |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| dc.title.fl_str_mv | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | In this work, the authors propose a new quick sol–gel procedure for bioglass nanoparticles production containing 10% mol of silver (AgBGs). These new AgBGs are characterized by Zeta potential analysis, scanning electron microscopy with X-ray microanalysis (SEM/EDS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and microbiological tests to confirm their bioactive and antibacterial properties. SEM shows that the average particle size is less than 200 nm and EDS confirms the successful incorporation of Ag2O in the bioglass matrix. XRD confirms the amorphous nature of the AgBGs and, after SBF immersion, reveals their bioactive behavior with the presence of crystalline phase of calcium silicate and phosphorus oxide, which are also detected by FTIR analysis. FTIR also confirms the formation of typical siloxane bonds resulting from the condensation of silicate glass. Lastly, it is found that the developed AgBGs has an antibacterial effect against two different types of bacteria, thus demonstrating their ability to reduce the bacterial infection within 16 h. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://prod-dspace.uminho.pt/bitstreams/ae03447c-9b27-4e49-88d2-c6bb1e0c676c/download |
| id | rum_aeafb22b6bca29dfbebfdbea2484ca6e |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/50827 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/50827 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Vale, Ana Catarina Carvalho, Ana Luísa Barbosa, Ana Margarida Martins Torrado, Egídio Mano, J. F. Alves, N. M. |
| publishDate | 2018 |
| publisher.none.fl_str_mv | Wiley |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engWileyporIn this work, the authors propose a new quick sol–gel procedure for bioglass nanoparticles production containing 10% mol of silver (AgBGs). These new AgBGs are characterized by Zeta potential analysis, scanning electron microscopy with X-ray microanalysis (SEM/EDS), X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and microbiological tests to confirm their bioactive and antibacterial properties. SEM shows that the average particle size is less than 200 nm and EDS confirms the successful incorporation of Ag2O in the bioglass matrix. XRD confirms the amorphous nature of the AgBGs and, after SBF immersion, reveals their bioactive behavior with the presence of crystalline phase of calcium silicate and phosphorus oxide, which are also detected by FTIR analysis. FTIR also confirms the formation of typical siloxane bonds resulting from the condensation of silicate glass. Lastly, it is found that the developed AgBGs has an antibacterial effect against two different types of bacteria, thus demonstrating their ability to reduce the bacterial infection within 16 h.application/pdfporNovel antibacterial and bioactive silicate glass nanoparticles for biomedical applicationsVale, Ana CatarinaCarvalho, Ana LuísaBarbosa, Ana Margarida MartinsTorrado, EgídioMano, J. F.Alves, N. M.HostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1438-1656DOIIsPartOf10.1002/adem.2017008552018-02-22T10:08:56Z20182018-01-25T10:23:41Z2018-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/50827http://purl.org/coar/access_right/c_abf2open accessAntibacterial propertiesBiomineralizationSilicate glassSilver doped nanoparticles628660 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/ae03447c-9b27-4e49-88d2-c6bb1e0c676c/download |
| spellingShingle | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications Vale, Ana Catarina Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| status | SINGLETON |
| subject.fl_str_mv | Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| title | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| title_full | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| title_fullStr | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| title_full_unstemmed | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| title_short | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| title_sort | Novel antibacterial and bioactive silicate glass nanoparticles for biomedical applications |
| topic | Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| topic_facet | Antibacterial properties Biomineralization Silicate glass Silver doped nanoparticles |
| url | https://hdl.handle.net/1822/50827 |
| visible | 1 |