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Self-assembled nanoparticles made of dextrin

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Detalhes bibliográficos
Resumo:The amphiphilic molecule dextrin-VA-SC16 (dexC16) was produced and studied in this work. DexC16 has a hydrophilic dextrin backbone with grafted acrylate groups (VA), substituted with hydrophobic 1- exadecanethiol (C16). The dextrin degree of substitution with the hydrophobic chains (DSC16, number of alkyl chains per 100 dextrin glucopyranoside residues) may be controlled. Materials with different DSC16 were prepared and characterized using ¹H NMR. DexC16 self assembles in water through association of the hydrophobic alkyl chains, originating hydrogel nanoparticles. The properties of the hydrogel nanoparticle were studied by dynamic light scattering (DLS), fluorescence spectroscopy and atomic force microscopy (AFM).
Autores principais:Gonçalves, Catarina
Outros Autores:Martins, J. A.; Gama, F. M.
Assunto:Nanoparticles Dextrin Self-assembling
Ano:2006
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
Descrição
Resumo:The amphiphilic molecule dextrin-VA-SC16 (dexC16) was produced and studied in this work. DexC16 has a hydrophilic dextrin backbone with grafted acrylate groups (VA), substituted with hydrophobic 1- exadecanethiol (C16). The dextrin degree of substitution with the hydrophobic chains (DSC16, number of alkyl chains per 100 dextrin glucopyranoside residues) may be controlled. Materials with different DSC16 were prepared and characterized using ¹H NMR. DexC16 self assembles in water through association of the hydrophobic alkyl chains, originating hydrogel nanoparticles. The properties of the hydrogel nanoparticle were studied by dynamic light scattering (DLS), fluorescence spectroscopy and atomic force microscopy (AFM).