Publicação
Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates
| Resumo: | Fibromyalgia (FM) is a generalized chronic pain condition associated with a variety of symptoms, including altered cognitive and emotional processing. It has been proposed that FM patients show a preferential allocation of attention to information related to the symptoms of the disease, particularly to pain cues. However, the existing literature does not provide conclusive evidence on the presence of this attentional bias, and its effect on cognitive functions such as inhibitory control. To clarify this issue, we recorded the electroencephalographic activity of 31 women diagnosed with FM and 28 healthy women, while performing an emotional Go/NoGo task with micro-videos of pain, happy, and neutral facial expressions. We analyzed behavioral data, performed EEG time-frequency analyses, and obtained the event-related potentials (ERPs) N2 and P3 components in NoGo trials. A series of self-reports was also administered to evaluate catastrophic thinking and the main symptoms of fibromyalgia. Pain expressions were associated with longer reaction times and more errors, as well as with higher theta and delta power, and P3 amplitude to NoGo stimuli. Thus, behavioral and psychophysiological data suggest that increased attention to pain expressions impairs the performance of an inhibitory task, although this effect was similar in FM patients and healthy controls. N2 amplitude was modulated by type of facial expression (larger to pain faces), but only for the control group. This finding suggests that the presentation of pain faces might represent a smaller conflict for the patients, more used to encounter pain stimuli. No main group effects were found significant for N2 or P3 amplitudes, nor for time-frequency data. Using stimuli with greater ecological validity than in previous studies, we could not confirm a greater effect of attentional bias toward negative stimuli over inhibitory performance in patients with FM. Studying these effects allow us to better understand the mechanisms that maintain pain and develop intervention strategies to modify them. |
|---|---|
| Autores principais: | Pidal-Miranda, Marina |
| Outros Autores: | González-Villar, Alberto J.; Carrillo-de-la-Peña, M. T. |
| Assunto: | Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control Ciências Sociais::Psicologia |
| Ano: | 2019 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1867438001154424832 |
|---|---|
| author | Pidal-Miranda, Marina |
| author2 | González-Villar, Alberto J. Carrillo-de-la-Peña, M. T. |
| author2_role | author author |
| author_facet | Pidal-Miranda, Marina González-Villar, Alberto J. Carrillo-de-la-Peña, M. T. |
| author_role | author |
| contributor_name_str_mv | RepositóriUM - Universidade do Minho |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Pidal-Miranda, Marina\"},{\"Person.name\":\"González-Villar, Alberto J.\"},{\"Person.name\":\"Carrillo-de-la-Peña, M. T.\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | RepositóriUM - Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Pidal-Miranda, Marina González-Villar, Alberto J. Carrillo-de-la-Peña, M. T. |
| datacite.date.Accepted.fl_str_mv | 2019-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2021-01-25T10:06:35Z |
| datacite.date.embargoed.fl_str_mv | 2021-01-25T10:06:35Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control Ciências Sociais::Psicologia |
| datacite.titles.title.fl_str_mv | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| dc.contributor.none.fl_str_mv | RepositóriUM - Universidade do Minho |
| dc.creator.none.fl_str_mv | Pidal-Miranda, Marina González-Villar, Alberto J. Carrillo-de-la-Peña, M. T. |
| dc.date.Accepted.fl_str_mv | 2019-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2021-01-25T10:06:35Z |
| dc.date.embargoed.fl_str_mv | 2021-01-25T10:06:35Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/69629 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Frontiers Media |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control Ciências Sociais::Psicologia |
| dc.title.fl_str_mv | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Fibromyalgia (FM) is a generalized chronic pain condition associated with a variety of symptoms, including altered cognitive and emotional processing. It has been proposed that FM patients show a preferential allocation of attention to information related to the symptoms of the disease, particularly to pain cues. However, the existing literature does not provide conclusive evidence on the presence of this attentional bias, and its effect on cognitive functions such as inhibitory control. To clarify this issue, we recorded the electroencephalographic activity of 31 women diagnosed with FM and 28 healthy women, while performing an emotional Go/NoGo task with micro-videos of pain, happy, and neutral facial expressions. We analyzed behavioral data, performed EEG time-frequency analyses, and obtained the event-related potentials (ERPs) N2 and P3 components in NoGo trials. A series of self-reports was also administered to evaluate catastrophic thinking and the main symptoms of fibromyalgia. Pain expressions were associated with longer reaction times and more errors, as well as with higher theta and delta power, and P3 amplitude to NoGo stimuli. Thus, behavioral and psychophysiological data suggest that increased attention to pain expressions impairs the performance of an inhibitory task, although this effect was similar in FM patients and healthy controls. N2 amplitude was modulated by type of facial expression (larger to pain faces), but only for the control group. This finding suggests that the presentation of pain faces might represent a smaller conflict for the patients, more used to encounter pain stimuli. No main group effects were found significant for N2 or P3 amplitudes, nor for time-frequency data. Using stimuli with greater ecological validity than in previous studies, we could not confirm a greater effect of attentional bias toward negative stimuli over inhibitory performance in patients with FM. Studying these effects allow us to better understand the mechanisms that maintain pain and develop intervention strategies to modify them. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://repositorium.uminho.pt/bitstreams/9d4fdbff-be8a-4591-b5c6-944c7cb35f0d/download |
| id | rum_c1f5fdeffb4a850cd2a33caf2b2a2c68 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/69629 |
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| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
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| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/69629 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Pidal-Miranda, Marina González-Villar, Alberto J. Carrillo-de-la-Peña, M. T. |
| publishDate | 2019 |
| publisher.none.fl_str_mv | Frontiers Media |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
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| spelling | engFrontiers MediaporFibromyalgia (FM) is a generalized chronic pain condition associated with a variety of symptoms, including altered cognitive and emotional processing. It has been proposed that FM patients show a preferential allocation of attention to information related to the symptoms of the disease, particularly to pain cues. However, the existing literature does not provide conclusive evidence on the presence of this attentional bias, and its effect on cognitive functions such as inhibitory control. To clarify this issue, we recorded the electroencephalographic activity of 31 women diagnosed with FM and 28 healthy women, while performing an emotional Go/NoGo task with micro-videos of pain, happy, and neutral facial expressions. We analyzed behavioral data, performed EEG time-frequency analyses, and obtained the event-related potentials (ERPs) N2 and P3 components in NoGo trials. A series of self-reports was also administered to evaluate catastrophic thinking and the main symptoms of fibromyalgia. Pain expressions were associated with longer reaction times and more errors, as well as with higher theta and delta power, and P3 amplitude to NoGo stimuli. Thus, behavioral and psychophysiological data suggest that increased attention to pain expressions impairs the performance of an inhibitory task, although this effect was similar in FM patients and healthy controls. N2 amplitude was modulated by type of facial expression (larger to pain faces), but only for the control group. This finding suggests that the presentation of pain faces might represent a smaller conflict for the patients, more used to encounter pain stimuli. No main group effects were found significant for N2 or P3 amplitudes, nor for time-frequency data. Using stimuli with greater ecological validity than in previous studies, we could not confirm a greater effect of attentional bias toward negative stimuli over inhibitory performance in patients with FM. Studying these effects allow us to better understand the mechanisms that maintain pain and develop intervention strategies to modify them.application/pdfporPain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlatesPidal-Miranda, MarinaGonzález-Villar, Alberto J.Carrillo-de-la-Peña, M. T.HostingInstitutionOrganizationalRepositóriUM - Universidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptCITATIONPidal-Miranda, M., González-Villar, A. J., & Carrillo-de-la-Peña, M. T. (2019). Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates. Frontiers in behavioral neuroscience, 12, 323ISSNIsPartOf1662-5153EISSNIsPartOf1662-5153DOIIsPartOf10.3389/fnbeh.2018.003232021-01-25T10:06:35Z2019-012018-072019-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/69629http://purl.org/coar/access_right/c_abf2open accessBrain electrical activityChronic painCognitive dysfunctionEmotionAttentionPainInhibitory controlhttp://www.oecd.org/science/inno/38235147.pdfFields of Science and Technology (FOS)Ciências Sociais::Psicologia2114478 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://repositorium.uminho.pt/bitstreams/9d4fdbff-be8a-4591-b5c6-944c7cb35f0d/download |
| spellingShingle | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates Pidal-Miranda, Marina Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control Ciências Sociais::Psicologia |
| status | SINGLETON |
| subject.fl_str_mv | Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control |
| subject.other.fl_str_mv | Ciências Sociais::Psicologia |
| title | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| title_full | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| title_fullStr | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| title_full_unstemmed | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| title_short | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| title_sort | Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates |
| topic | Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control Ciências Sociais::Psicologia |
| topic_facet | Brain electrical activity Chronic pain Cognitive dysfunction Emotion Attention Pain Inhibitory control Ciências Sociais::Psicologia |
| url | https://hdl.handle.net/1822/69629 |
| visible | 1 |