Publicação
The price of cost-effectiveness thresholds
| Resumo: | Health systems around world are increasingly adopting cost-effectiveness (CE) analysis to inform decisions about access and reimbursement. We study how CE thresholds imposed by a health plan for granting reimbursement affect drug producers´ pricing incentives and patients´access to new drugs. Analysing a sequential pricing game between an incumbent drug producer and a potential entrant with a new drug, we show that CE thresholds may have adverse effects for payers and patients. A stricter CE threshold may induce the incumbent to switch pricing strategy from entry accommodation to entry deterrence, limiting patients´ access to the new drug. Otherwise, irrespective of whether entry is deterred or accommodated, a stricter CE threshold is never pro-competitive and may in fact facilitate a collusive outcome with higher prices of both drugs. Compared to a laissez-faire policy, the use of CE thresholds can only increase the surplus of a health plan if it leads to entry deterrence in which the price reduction by the incumbent necessary to deter entry outweighs the health loss to patients not getting access to the new drug. |
|---|---|
| Autores principais: | Brekke, Kurt R. |
| Outros Autores: | Dalen, Dag Morten; Straume, Odd Rune |
| Assunto: | Pharmaceuticals Health Plans Cost-effectiveness analysis ICER Therapeutic competition |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | working paper |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
Registos relacionados
school Cost-effectiveness of colorectal screening in Portugal : was biennial FIT a good choice?
por: Lopes, Luís Miguel da Silva Araújo
Publicado em: (2022)
por: Lopes, Luís Miguel da Silva Araújo
Publicado em: (2022)
draft Taking the competitor's pill: when combination therapies enter pharmaceutical markets
por: Brekke, Kurt R.
Publicado em: (2023)
por: Brekke, Kurt R.
Publicado em: (2023)
draft Competing with precision: incentives for developing predictive biomarker tests
por: Brekke, Kurt R.
Publicado em: (2022)
por: Brekke, Kurt R.
Publicado em: (2022)
draft Paying for pharmaceuticals: uniform pricing versus two-part tariffs
por: Brekke, Kurt R.
Publicado em: (2021)
por: Brekke, Kurt R.
Publicado em: (2021)
draft Regulation, generic competition and pharmaceutical prices : theory and evidence from a natural experiment
por: Brekke, Kurt R.
Publicado em: (2008)
por: Brekke, Kurt R.
Publicado em: (2008)
article Reference pricing, competition, and pharmaceutical expenditures : theory and evidence from a natural experiment
por: Brekke, Kurt R.
Publicado em: (2011)
por: Brekke, Kurt R.
Publicado em: (2011)
article Price and quality in spatial competition
por: Brekke, Kurt R.
Publicado em: (2010)
por: Brekke, Kurt R.
Publicado em: (2010)
draft Hospital mergers with regulated prices
por: Brekke, Kurt R.
Publicado em: (2014)
por: Brekke, Kurt R.
Publicado em: (2014)
article Paying for pharmaceuticals: uniform pricing versus two-part tariffs
por: Brekke, Kurt R.
Publicado em: (2022)
por: Brekke, Kurt R.
Publicado em: (2022)
school Impacto económico das quedas hospitalares em idosos : Um estudo sobre a dinâmica de prevenção e gestão do risco de queda da área de Medicina Interna da ULS São José
por: Silva, Mónica Isabel Nunes
Publicado em: (2025)
por: Silva, Mónica Isabel Nunes
Publicado em: (2025)
article Reference pricing of pharmaceuticals
por: Brekke, Kurt R.
Publicado em: (2007)
por: Brekke, Kurt R.
Publicado em: (2007)
article Simplified mathematical modelling of uncertainty
por: Marco-Franco, Julio Emilio
Publicado em: (2021)
por: Marco-Franco, Julio Emilio
Publicado em: (2021)
draft Price regulation and parallel imports of pharmaceuticals
por: Brekke, Kurt R.
Publicado em: (2014)
por: Brekke, Kurt R.
Publicado em: (2014)
draft Hospital competition and quality with regulated prices
por: Brekke, Kurt R.
Publicado em: (2008)
por: Brekke, Kurt R.
Publicado em: (2008)
draft Hospital competition with soft budgets
por: Brekke, Kurt R.
Publicado em: (2012)
por: Brekke, Kurt R.
Publicado em: (2012)
article Cost Comparison Between Defocus Spectacle Lens and Compound Atropine in Myopia Treatment in the Portuguese Setting
por: Barros da Silva, P
Publicado em: (2024)
por: Barros da Silva, P
Publicado em: (2024)
school One. cost – assessing social problems' costs
por: Gomes, Joana Rita da Fonseca
Publicado em: (2017)
por: Gomes, Joana Rita da Fonseca
Publicado em: (2017)
article Bilateral monopolies and location choice
por: Brekke, Kurt R.
Publicado em: (2004)
por: Brekke, Kurt R.
Publicado em: (2004)
draft Reference pricing with endogenous generic entry
por: Brekke, Kurt R.
Publicado em: (2015)
por: Brekke, Kurt R.
Publicado em: (2015)
draft Competition matters: uniform vs. indication-based pricing of pharmaceuticals
por: Brekke, Kurt R.
Publicado em: (2025)
por: Brekke, Kurt R.
Publicado em: (2025)
article Reference pricing with endogenous generic entry
por: Brekke, Kurt R.
Publicado em: (2016)
por: Brekke, Kurt R.
Publicado em: (2016)
article Ecotoxicological effects of ciprofloxacin on freshwater species: data integration and derivation of toxicity thresholds for risk assessment
por: Martins, N.
Publicado em: (2012)
por: Martins, N.
Publicado em: (2012)
draft Hospital Competition in the National Health Service: Evidence from a Patient Choice Reform
por: Brekke, Kurt R.
Publicado em: (2018)
por: Brekke, Kurt R.
Publicado em: (2018)
draft Brand effects, mobility costs and industry evolution
por: Mamede, R.
Publicado em: (2005)
por: Mamede, R.
Publicado em: (2005)
article Hospital competition and quality with regulated prices
por: Brekke, Kurt R.
Publicado em: (2011)
por: Brekke, Kurt R.
Publicado em: (2011)
article Waste-based biosorbents as cost-effective alternatives to commercial adsorbents for the retention of fluoxetine from water
por: Silva, Bruna
Publicado em: (2020)
por: Silva, Bruna
Publicado em: (2020)
draft Does reference pricing drive out generic competition in pharmaceutical markets? Evidence from a policy reform
por: Brekke, Kurt R.
Publicado em: (2015)
por: Brekke, Kurt R.
Publicado em: (2015)
school Price linkages in pharmaceutical markets
por: Martins, Bruno Duarte Fonseca
Publicado em: (2012)
por: Martins, Bruno Duarte Fonseca
Publicado em: (2012)
article Cost-effectiveness of Semaglutide 2.4 mg in chronic weight management in Portugal
por: Silva Miguel, Luís
Publicado em: (2024)
por: Silva Miguel, Luís
Publicado em: (2024)
draft Hospital competition under patient inertia: do switching costs stimulate quality provision?
por: Sá, Luís Carlos Sousa
Publicado em: (2019)
por: Sá, Luís Carlos Sousa
Publicado em: (2019)
article Price regulation and parallel imports of pharmaceuticals
por: Brekke, Kurt R.
Publicado em: (2015)
por: Brekke, Kurt R.
Publicado em: (2015)
article Evolution of price‑cost margins during the troika intervention Portugal : market competition and workers’ bargaining power in 2010-2016
por: Figueira, Carlos
Publicado em: (2023)
por: Figueira, Carlos
Publicado em: (2023)
school Low-cost carriers as disruptors to classic airline companies
por: Culin, Filip Palinic
Publicado em: (2020)
por: Culin, Filip Palinic
Publicado em: (2020)
article Competition and quality in regulated markets: a differential-game approach
por: Brekke, Kurt R.
Publicado em: (2010)
por: Brekke, Kurt R.
Publicado em: (2010)
article Cost-Effectiveness of Non-Vitamin K Antagonist Oral Anticoagulants for Atrial Fibrillation in Portugal
por: Costa, J
Publicado em: (2015)
por: Costa, J
Publicado em: (2015)
school Continuous versus batch manufacturing of oral dosage forms: analysis of current worldwide implementation
por: Rodrigues, Andreia Afonso
Publicado em: (2021)
por: Rodrigues, Andreia Afonso
Publicado em: (2021)
article A quantitative analysis on the effects of critical factors limiting the effectiveness of species conservation in future-time
por: Alagador, Diogo
Publicado em: (2020)
por: Alagador, Diogo
Publicado em: (2020)
article Spatial competition under uniform delivered pricing
por: Pontes, José Pedro
Publicado em: (1987)
por: Pontes, José Pedro
Publicado em: (1987)
article Survival Impact and Cost-Effectiveness of a Multidisciplinary Tumor Board for Breast Cancer in Mozambique, Sub-Saharan Africa
por: Brandão, M
Publicado em: (2021)
por: Brandão, M
Publicado em: (2021)
article Cost-effectiveness analysis for sustainable wastewater engineering : a case study at Minho-Lima’s rivers basins (Portugal)
por: Costa, Sérgio
Publicado em: (2007)
por: Costa, Sérgio
Publicado em: (2007)
Registos relacionados
-
school Cost-effectiveness of colorectal screening in Portugal : was biennial FIT a good choice?
por: Lopes, Luís Miguel da Silva Araújo
Publicado em: (2022) -
draft Taking the competitor's pill: when combination therapies enter pharmaceutical markets
por: Brekke, Kurt R.
Publicado em: (2023) -
draft Competing with precision: incentives for developing predictive biomarker tests
por: Brekke, Kurt R.
Publicado em: (2022) -
draft Paying for pharmaceuticals: uniform pricing versus two-part tariffs
por: Brekke, Kurt R.
Publicado em: (2021) -
draft Regulation, generic competition and pharmaceutical prices : theory and evidence from a natural experiment
por: Brekke, Kurt R.
Publicado em: (2008)