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Selection of aptamers to target enterotoxigenic Escherichia coli infections

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Resumo:[Excerpt] Introduction Enterotoxigenic Escherichia coli (ETEC) is the leading cause of enteric infections in swine, resulting in significant costs for the industry (1 ). Initial adhesion to the intestinal epithelium relies on fimbriae, with F4 and F18 types being most associated with enteric infections. The traditional use of antibiotics for prevention and treatment is increasingly restricted due to rising antimicrobial resistance (2). Therefore, innovative strategies such as aptamers- small single-stranded oligonucleotides that bind to target molecules through their 3D structures (Figure 1 )- emerge as a promising alternative.[...]
Autores principais:Campos, Ana Maria
Outros Autores:Barros, Maria Margarida; Oliveira, Ricardo; Castro, Joana Isabel Reis; Araújo, Daniela Eira; Outor-Monteiro, Divanildo; Almeida, Carina Manuela Fernandes
Ano:2025
País:Portugal
Tipo de documento:póster em conferência
Tipo de acesso:acesso aberto
Instituição associada:Universidade do Minho
Idioma:inglês
Origem:RepositóriUM - Universidade do Minho
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author Campos, Ana Maria
author2 Barros, Maria Margarida
Oliveira, Ricardo
Castro, Joana Isabel Reis
Araújo, Daniela Eira
Outor-Monteiro, Divanildo
Almeida, Carina Manuela Fernandes
author2_role author
author
author
author
author
author
author_facet Campos, Ana Maria
Barros, Maria Margarida
Oliveira, Ricardo
Castro, Joana Isabel Reis
Araújo, Daniela Eira
Outor-Monteiro, Divanildo
Almeida, Carina Manuela Fernandes
author_role author
contributor_name_str_mv Universidade do Minho
country_str PT
creators_json_txt [{\"Person.name\":\"Campos, Ana Maria\"},{\"Person.name\":\"Barros, Maria Margarida\"},{\"Person.name\":\"Oliveira, Ricardo\"},{\"Person.name\":\"Castro, Joana Isabel Reis\"},{\"Person.name\":\"Araújo, Daniela Eira\"},{\"Person.name\":\"Outor-Monteiro, Divanildo\"},{\"Person.name\":\"Almeida, Carina Manuela Fernandes\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Universidade do Minho
datacite.creators.creator.creatorName.fl_str_mv Campos, Ana Maria
Barros, Maria Margarida
Oliveira, Ricardo
Castro, Joana Isabel Reis
Araújo, Daniela Eira
Outor-Monteiro, Divanildo
Almeida, Carina Manuela Fernandes
datacite.date.Accepted.fl_str_mv 2025-03-21T00:00:00Z
datacite.date.available.fl_str_mv 2025-06-09T09:31:31Z
datacite.date.embargoed.fl_str_mv 2025-06-09T09:31:31Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.titles.title.fl_str_mv Selection of aptamers to target enterotoxigenic Escherichia coli infections
dc.contributor.none.fl_str_mv Universidade do Minho
dc.creator.none.fl_str_mv Campos, Ana Maria
Barros, Maria Margarida
Oliveira, Ricardo
Castro, Joana Isabel Reis
Araújo, Daniela Eira
Outor-Monteiro, Divanildo
Almeida, Carina Manuela Fernandes
dc.date.Accepted.fl_str_mv 2025-03-21T00:00:00Z
dc.date.available.fl_str_mv 2025-06-09T09:31:31Z
dc.date.embargoed.fl_str_mv 2025-06-09T09:31:31Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv https://hdl.handle.net/1822/96059
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.title.fl_str_mv Selection of aptamers to target enterotoxigenic Escherichia coli infections
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6670
description [Excerpt] Introduction Enterotoxigenic Escherichia coli (ETEC) is the leading cause of enteric infections in swine, resulting in significant costs for the industry (1 ). Initial adhesion to the intestinal epithelium relies on fimbriae, with F4 and F18 types being most associated with enteric infections. The traditional use of antibiotics for prevention and treatment is increasingly restricted due to rising antimicrobial resistance (2). Therefore, innovative strategies such as aptamers- small single-stranded oligonucleotides that bind to target molecules through their 3D structures (Figure 1 )- emerge as a promising alternative.[...]
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id rum_d06a64e27807be21eee665cf5c382cd5
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organization_str_mv urn:organizationAcronym:repositorium
person_str_mv Campos, Ana Maria
Barros, Maria Margarida
Oliveira, Ricardo
Castro, Joana Isabel Reis
Araújo, Daniela Eira
Outor-Monteiro, Divanildo
Almeida, Carina Manuela Fernandes
publishDate 2025
reponame_str RepositóriUM - Universidade do Minho
repository_id_str urn:repositoryAcronym:rum
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spelling engpor[Excerpt] Introduction Enterotoxigenic Escherichia coli (ETEC) is the leading cause of enteric infections in swine, resulting in significant costs for the industry (1 ). Initial adhesion to the intestinal epithelium relies on fimbriae, with F4 and F18 types being most associated with enteric infections. The traditional use of antibiotics for prevention and treatment is increasingly restricted due to rising antimicrobial resistance (2). Therefore, innovative strategies such as aptamers- small single-stranded oligonucleotides that bind to target molecules through their 3D structures (Figure 1 )- emerge as a promising alternative.[...]application/pdfporSelection of aptamers to target enterotoxigenic Escherichia coli infectionsCampos, Ana MariaBarros, Maria MargaridaOliveira, RicardoCastro, Joana Isabel ReisAraújo, Daniela EiraOutor-Monteiro, DivanildoAlmeida, Carina Manuela FernandesHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.pt2025-06-09T09:31:31Z2025-03-212025-05-22T11:26:28Z2025-03-21T00:00:00ZHandlehttps://hdl.handle.net/1822/96059http://purl.org/coar/access_right/c_abf2open access446200 bytesother research producthttp://purl.org/coar/resource_type/c_6670conference posterhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/8d1d4251-7a24-435f-8327-648e0e005cf4/download
spellingShingle Selection of aptamers to target enterotoxigenic Escherichia coli infections
Campos, Ana Maria
status SINGLETON
title Selection of aptamers to target enterotoxigenic Escherichia coli infections
title_full Selection of aptamers to target enterotoxigenic Escherichia coli infections
title_fullStr Selection of aptamers to target enterotoxigenic Escherichia coli infections
title_full_unstemmed Selection of aptamers to target enterotoxigenic Escherichia coli infections
title_short Selection of aptamers to target enterotoxigenic Escherichia coli infections
title_sort Selection of aptamers to target enterotoxigenic Escherichia coli infections
url https://hdl.handle.net/1822/96059
visible 1