Publicação
Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds
| Resumo: | The present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds. |
|---|---|
| Autores principais: | Pinho, Eva |
| Outros Autores: | Ferreira, Isabel C. F. R.; Barros, Lillian; Carvalho, Ana Maria; Soares, Graça M. B.; Henriques, Mariana |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1864252106820550656 |
|---|---|
| author | Pinho, Eva |
| author2 | Ferreira, Isabel C. F. R. Barros, Lillian Carvalho, Ana Maria Soares, Graça M. B. Henriques, Mariana |
| author2_role | author author author author author |
| author_facet | Pinho, Eva Ferreira, Isabel C. F. R. Barros, Lillian Carvalho, Ana Maria Soares, Graça M. B. Henriques, Mariana |
| author_role | author |
| contributor_name_str_mv | Universidade do Minho |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Pinho, Eva\"},{\"Person.name\":\"Ferreira, Isabel C. F. R.\"},{\"Person.name\":\"Barros, Lillian\"},{\"Person.name\":\"Carvalho, Ana Maria\"},{\"Person.name\":\"Soares, Graça M. B.\"},{\"Person.name\":\"Henriques, Mariana\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Pinho, Eva Ferreira, Isabel C. F. R. Barros, Lillian Carvalho, Ana Maria Soares, Graça M. B. Henriques, Mariana |
| datacite.date.Accepted.fl_str_mv | 2014-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2014-12-11T18:10:54Z |
| datacite.date.embargoed.fl_str_mv | 2014-12-11T18:10:54Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.titles.title.fl_str_mv | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| dc.contributor.none.fl_str_mv | Universidade do Minho |
| dc.creator.none.fl_str_mv | Pinho, Eva Ferreira, Isabel C. F. R. Barros, Lillian Carvalho, Ana Maria Soares, Graça M. B. Henriques, Mariana |
| dc.date.Accepted.fl_str_mv | 2014-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2014-12-11T18:10:54Z |
| dc.date.embargoed.fl_str_mv | 2014-12-11T18:10:54Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/31888 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Hindawi Publishing Corporation |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.title.fl_str_mv | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | The present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://prod-dspace.uminho.pt/bitstreams/361b7e1e-4475-4882-8bd1-8c32a9f80263/download |
| id | rum_d76ec71fb5eaf03fa5a9f60132f97ffc |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/31888 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/31888 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Pinho, Eva Ferreira, Isabel C. F. R. Barros, Lillian Carvalho, Ana Maria Soares, Graça M. B. Henriques, Mariana |
| publishDate | 2014 |
| publisher.none.fl_str_mv | Hindawi Publishing Corporation |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engHindawi Publishing CorporationporThe present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compounds. The effect of selected phenolic compounds on animal cells was assessed by determination of cellular metabolic activity. Gallic acid had a higher activity, against gram-positive (S. epidermidis and S. aureus) and gram-negative bacteria (K. pneumoniae) at lower concentrations, than the other compounds. The caffeic acid, also, showed good antibacterial activity against the 3 bacteria used. The gallic acid was effective against the 3 bacteria without causing harm to the animal cells. Gallic and caffeic acid showed a promising applicability as antibacterial agents for the treatment of infected wounds.application/pdfporAntibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compoundsPinho, EvaFerreira, Isabel C. F. R.Barros, LillianCarvalho, Ana MariaSoares, Graça M. B.Henriques, MarianaHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf2314-6133DOIIsPartOf10.1155/2014/8145902014-12-11T18:10:54Z20142014-11-28T17:56:29Z2014-01-01T00:00:00ZHandlehttps://hdl.handle.net/1822/31888http://purl.org/coar/access_right/c_abf2open access438943 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/361b7e1e-4475-4882-8bd1-8c32a9f80263/download |
| spellingShingle | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds Pinho, Eva |
| title | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| title_full | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| title_fullStr | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| title_full_unstemmed | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| title_short | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| title_sort | Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds |
| url | https://hdl.handle.net/1822/31888 |
| visible | 1 |