Publicação
Permeation of skin with (C60) fullerene dispersions
| Resumo: | Dispersions in transcutol/isopropyl myristate make C60 fullerene molecules suitable for transdermal delivery. We found that C60 can successfully permeate the skin using pig skin in Franz diffusion cells. Molecular dynamics simulations and transmission electron microscopy confirmed these observations. Basic cosmetic formulations with transcutol/ isopropyl myristate without harsh organic solvents show a high potential for delivery of C60 for biopharmaceutical and cosmetics applications. |
|---|---|
| Autores principais: | Sá, M. |
| Outros Autores: | Azóia, Nuno G.; Melle-Franco, Manuel; Ribeiro, Artur; Cavaco-Paulo, Artur |
| Assunto: | Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade do Minho |
| Idioma: | inglês |
| Origem: | RepositóriUM - Universidade do Minho |
| _version_ | 1864252108397608960 |
|---|---|
| author | Sá, M. |
| author2 | Azóia, Nuno G. Melle-Franco, Manuel Ribeiro, Artur Cavaco-Paulo, Artur |
| author2_role | author author author author |
| author_facet | Sá, M. Azóia, Nuno G. Melle-Franco, Manuel Ribeiro, Artur Cavaco-Paulo, Artur |
| author_role | author |
| contributor_name_str_mv | Universidade do Minho |
| country_str | PT |
| creators_json_str | [{\"Person.name\":\"Sá, M.\"},{\"Person.name\":\"Azóia, Nuno G.\"},{\"Person.name\":\"Melle-Franco, Manuel\"},{\"Person.name\":\"Ribeiro, Artur\"},{\"Person.name\":\"Cavaco-Paulo, Artur\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Universidade do Minho |
| datacite.creators.creator.creatorName.fl_str_mv | Sá, M. Azóia, Nuno G. Melle-Franco, Manuel Ribeiro, Artur Cavaco-Paulo, Artur |
| datacite.date.Accepted.fl_str_mv | 2017-07-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2017-09-11T10:54:57Z |
| datacite.date.embargoed.fl_str_mv | 2017-09-11T10:54:57Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| datacite.titles.title.fl_str_mv | Permeation of skin with (C60) fullerene dispersions |
| dc.contributor.none.fl_str_mv | Universidade do Minho |
| dc.creator.none.fl_str_mv | Sá, M. Azóia, Nuno G. Melle-Franco, Manuel Ribeiro, Artur Cavaco-Paulo, Artur |
| dc.date.Accepted.fl_str_mv | 2017-07-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2017-09-11T10:54:57Z |
| dc.date.embargoed.fl_str_mv | 2017-09-11T10:54:57Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/1822/46390 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Wiley-Blackwell |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| dc.title.fl_str_mv | Permeation of skin with (C60) fullerene dispersions |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Dispersions in transcutol/isopropyl myristate make C60 fullerene molecules suitable for transdermal delivery. We found that C60 can successfully permeate the skin using pig skin in Franz diffusion cells. Molecular dynamics simulations and transmission electron microscopy confirmed these observations. Basic cosmetic formulations with transcutol/ isopropyl myristate without harsh organic solvents show a high potential for delivery of C60 for biopharmaceutical and cosmetics applications. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://prod-dspace.uminho.pt/bitstreams/11fed73b-c7e3-44b3-9347-086a1b99f08b/download |
| id | rum_dfd824f26fff57971cfa2ca53ff986c3 |
| identifier.url.fl_str_mv | https://hdl.handle.net/1822/46390 |
| instacron_str | repositorium |
| institution | Universidade do Minho |
| instname_str | Universidade do Minho |
| language | eng |
| network_acronym_str | rum |
| network_name_str | RepositóriUM - Universidade do Minho |
| oai_identifier_str | oai:repositorium.uminho.pt:1822/46390 |
| organization_str_mv | urn:organizationAcronym:repositorium |
| person_str_mv | Sá, M. Azóia, Nuno G. Melle-Franco, Manuel Ribeiro, Artur Cavaco-Paulo, Artur |
| publishDate | 2017 |
| publisher.none.fl_str_mv | Wiley-Blackwell |
| reponame_str | RepositóriUM - Universidade do Minho |
| repository_id_str | urn:repositoryAcronym:rum |
| service_str_mv | urn:repositoryAcronym:rum |
| spelling | engWiley-BlackwellporDispersions in transcutol/isopropyl myristate make C60 fullerene molecules suitable for transdermal delivery. We found that C60 can successfully permeate the skin using pig skin in Franz diffusion cells. Molecular dynamics simulations and transmission electron microscopy confirmed these observations. Basic cosmetic formulations with transcutol/ isopropyl myristate without harsh organic solvents show a high potential for delivery of C60 for biopharmaceutical and cosmetics applications.application/pdfporPermeation of skin with (C60) fullerene dispersionsSá, M.Azóia, Nuno G.Melle-Franco, ManuelRibeiro, ArturCavaco-Paulo, ArturHostingInstitutionOrganizationalUniversidade do Minhoe-mailmailto:repositorium@usdb.uminho.ptrepositorium@usdb.uminho.ptISSNIsPartOf1618-0240DOIIsPartOf10.1002/elsc.2016002442017-09-11T10:54:57Z2017-072017-08-03T11:01:25Z2017-07-01T00:00:00ZHandlehttps://hdl.handle.net/1822/46390http://purl.org/coar/access_right/c_abf2open accessDeliveryDispersionFullerene C60TransdermalCosmetics1077358 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://prod-dspace.uminho.pt/bitstreams/11fed73b-c7e3-44b3-9347-086a1b99f08b/download |
| spellingShingle | Permeation of skin with (C60) fullerene dispersions Sá, M. Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| subject.fl_str_mv | Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| title | Permeation of skin with (C60) fullerene dispersions |
| title_full | Permeation of skin with (C60) fullerene dispersions |
| title_fullStr | Permeation of skin with (C60) fullerene dispersions |
| title_full_unstemmed | Permeation of skin with (C60) fullerene dispersions |
| title_short | Permeation of skin with (C60) fullerene dispersions |
| title_sort | Permeation of skin with (C60) fullerene dispersions |
| topic | Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| topic_facet | Delivery Dispersion Fullerene C60 Transdermal Cosmetics |
| url | https://hdl.handle.net/1822/46390 |
| visible | 1 |